Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From positions in Jackson and the Gulf Coast to opportunities in communities across the state, find roles that match your experience, skills, and career goals.

Professional Opportunities Across Mississippi

Mississippi employers hire experienced professionals across industries such as healthcare, finance, manufacturing, technology, energy, and business operations. Available roles and compensation vary by employer, location, and qualifications, so review each listing for details about responsibilities, salary, and requirements.

Search in Mississippi Cities and Regions

Find opportunities in major employment centers including Jackson, Gulfport, and Southaven, as well as other Mississippi communities. Use location and job-title filters to focus your search, and consider remote or hybrid listings when available.

Find a Role That Fits Your Career

Compare opportunities by seniority, specialty, and work arrangement. Keep your résumé current, highlight measurable results, and tailor your application to the qualifications in each listing. Ladders helps professionals explore vetted jobs with salaries of at least $100,000.

Start Your Mississippi Job Search

Browse Mississippi jobs on Ladders and take the next step toward a professional opportunity aligned with your expertise and compensation goals. Listings change frequently, so check back for new roles.

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$100K - $120K *

Elevate customer relationships by managing and growing strategic national accounts. Focus on retention, upselling, and cross-selling within the Collision and Mechanical sectors while leveraging SaaS s...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Consumer Technology

$110K - $130K *

Transform the cybersecurity landscape by driving revenue growth and building strong customer relationships in the mid-market segment. Leverage consultative selling and AI-driven solutions to engage te...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Information Technology

$128K - $192K *

Unlock potential by driving new business growth through actionable health intelligence. Build relationships, identify client needs, and showcase solutions to enhance employee wellbeing and manage heal...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$110K - $120K *

Drive revenue growth by leading high-performing sales teams and executing strategic sales initiatives. This role combines leadership with deep expertise in performance marketing to achieve ambitious b...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Media

$125K - $175K *

Transform client relationships by driving value and engagement in a fast-growing segment. Leverage product expertise to manage renewals and upsell opportunities while contributing to best practices wi...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$144K - $200K *

Lead the charge in developing a high-performing sales team focused on public safety. Drive recruitment, coaching, and retention while ensuring team success through strategic deal management and AI int...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Consumer Technology

$90K - $110K *

Unlock potential by driving new business sales in a dynamic, AI-enabled environment. Own your territory, create a robust pipeline, and engage sophisticated buyers to deliver consistent revenue growth...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

$110K - $130K *

Unlock your potential as a strategic advisor, driving enterprise success on Amazon. Manage complex initiatives, build executive partnerships, and deliver transformative results through innovative adve...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Engage key customers to maximize revenue and profitability through strategic account planning, fostering value-driven relationships, and enhancing collaboration across business units for long-term gro...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Drive impactful digital media strategies by leading insights and innovation. Collaborate with clients to optimize media investments, manage a talented team, and present actionable insights that enhanc...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Business Services

$150K - $200K *

Lead the charge in delivering complex federal digital services programs, ensuring strategic direction, operational excellence, and strong customer relationships across multidisciplinary teams while ma...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$135K - $160K *

Contribute to the success of a dynamic sales team by managing key accounts, leading a team of specialists, and driving advocacy for innovative hematology solutions. Collaborate cross-functionally to e...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$144K - $200K *

Lead a national team of Key Account Leaders to drive sales in campus public safety, focusing on recruitment, coaching, and team performance. Shape strategies to enhance sales effectiveness and adapt t...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Consumer Technology

$235K - $315K *

Join a mission-driven team to drive growth within law enforcement and first responder agencies. Utilize your unique background to build relationships, close deals, and expand accounts in a high-perfor...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$145K - $175K *

Champion EPAM's growth by leading Advisor Relations strategy across North America. Build trusted relationships with sourcing advisors to drive commercial opportunities and enhance market perception, a...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Information Technology

$60K - $120K *

Take ownership of customer relationships to drive upgrades and maximize value. Engage with existing clients, manage the full sales cycle, and build trust to enhance their experience with our platform...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $110K *

Join a team that's driving growth by identifying and closing new client opportunities in experiential marketing. Leverage your network and expertise to engage youth and Gen Z through innovative campai...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Media

$135K - $160K *

Unlock potential by leading a dynamic sales team in hematology, driving strategic account management and fostering key stakeholder relationships to enhance the clinical experience with ZYNLONTA across...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Engage in full-cycle sales by identifying and closing new client opportunities, focusing on experiential marketing solutions for youth and Gen Z. Build relationships, manage pipelines, and achieve sal...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Media

$155K - $185K *

Partner with us to lead high-impact projects in healthcare marketing, managing budgets and teams while ensuring creative excellence and strategic alignment. Drive client success through collaboration...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Accelerate progress at a dynamic automotive SaaS company by owning the Mid-Market segment. Drive new business with multi-location auto repair groups, shaping strategies and building a scalable sales p...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Join our team to drive revenue growth by winning new business and establishing strategic relationships with key accounts. Collaborate with senior management to develop effective strategies and ensure...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Consumer Technology

$179K - $248K *

Lead the charge in operationalizing strategy and driving cross-division initiatives. Collaborate with senior stakeholders to enhance efficiency and client satisfaction in a fast-paced corporate travel...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$192K - $266K *

Drive best-in-class travel support through strategic leadership and operational excellence. Oversee lodging, flights, and customer advocacy, fostering a culture of continuous improvement and exception...

United StatesRemote

Reposted 1 week ago

  •   11 - 15 years exp.  •   Enterprise Technology

$150K - $180K *

Lead a dynamic account management team, driving strategic relationships with major health systems. Foster high-touch engagement, ensuring customer success and operational excellence while directly man...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of jobs can I find in Mississippi on Ladders?question toggle

    You can explore professional opportunities across fields such as healthcare, finance, manufacturing, technology, energy, and business operations. Roles and availability vary over time.

  • Are Mississippi jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional jobs that pay $100,000 or more. Check each listing for compensation details, qualifications, and other job-specific information.

  • Where in Mississippi can I search for jobs?question toggle

    Search across the state, including employment centers such as Jackson, Gulfport, and Southaven. You can use location filters to narrow results.

  • How can I find remote or hybrid jobs based in Mississippi?question toggle

    Use available work-arrangement filters or review listing details to identify remote and hybrid opportunities. Availability depends on the employer and role.

  • How do I improve my chances of getting hired for a Mississippi job?question toggle

    Tailor your résumé to the role, emphasize relevant experience and measurable outcomes, and ensure you meet the listed qualifications before applying.