Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From positions in Jackson and the Gulf Coast to opportunities in communities across the state, find roles that match your experience, skills, and career goals.

Professional Opportunities Across Mississippi

Mississippi employers hire experienced professionals across industries such as healthcare, finance, manufacturing, technology, energy, and business operations. Available roles and compensation vary by employer, location, and qualifications, so review each listing for details about responsibilities, salary, and requirements.

Search in Mississippi Cities and Regions

Find opportunities in major employment centers including Jackson, Gulfport, and Southaven, as well as other Mississippi communities. Use location and job-title filters to focus your search, and consider remote or hybrid listings when available.

Find a Role That Fits Your Career

Compare opportunities by seniority, specialty, and work arrangement. Keep your résumé current, highlight measurable results, and tailor your application to the qualifications in each listing. Ladders helps professionals explore vetted jobs with salaries of at least $100,000.

Start Your Mississippi Job Search

Browse Mississippi jobs on Ladders and take the next step toward a professional opportunity aligned with your expertise and compensation goals. Listings change frequently, so check back for new roles.

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$64K - $162K *

Transform creative visions into reality by leading a talented design team, driving innovative strategies, and ensuring high-quality project execution across various media platforms while collaborating...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$140K - $170K *

Champion the go-to-market strategy for streaming advertising, leading a product marketing team to craft compelling messaging and drive revenue growth. Collaborate across departments to ensure alignmen...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Media

$175K - $200K *

Drive strategic medical initiatives in Rare Neurology, collaborating with cross-functional teams to enhance patient outcomes. Leverage your expertise to shape launch strategies and foster relationship...

RemoteRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$170K - $200K *

Transform your career by leading a high-performing sales team, driving strategic growth, and enhancing client relationships in a dynamic, global environment. Leverage your expertise in IoT solutions t...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Transportation

$75K - $125K *

Empower growth by driving strategic account management and sales initiatives. Collaborate with diverse teams to deliver innovative manufacturing solutions, ensuring client success and exceeding revenu...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$120K - $145K *

Transform the future of tax compliance by building a scalable filing platform and remittance infrastructure, enabling seamless global transactions and automation for international sellers. Drive innov...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$103K - $128K *

Join us to lead product strategy and development, driving innovation and performance in healthcare solutions. Collaborate cross-functionally to align business needs with customer expectations and ensu...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $130K *

Engage with K-12 districts to drive cross-sell revenue, leveraging existing relationships to introduce new product lines. Collaborate with teams to enhance student safety through technology while mana...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$420K - $476K *

Elevate your career by driving Employer Sales growth, shaping go-to-market strategies, and building a high-performing sales organization. This strategic role requires strong leadership and expertise i...

United StatesRemote

Reposted 3 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$75K - $90K *

Champion client success by managing media dashboard projects and audience creation across multiple accounts. Collaborate with teams to ensure accurate tracking and actionable insights, driving perform...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Media

$108K - $122K *

Champion exceptional corporate events by leading strategy, design, and execution of high-impact experiences for clients and executives, ensuring alignment with business goals and delivering premium se...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$150K - $180K *

Transform enterprise relationships by driving strategic sales and fostering long-term partnerships in a dynamic AI infrastructure environment, engaging with C-level executives and guiding them through...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$229K - $458K *

Champion strategic growth initiatives in advanced manufacturing, driving business development and forging key partnerships. Collaborate with cross-functional teams to enhance service offerings and mee...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Explore innovative AI workflow solutions aimed at enhancing business processes. Collaborate with various teams to identify challenges, prototype solutions, and guide projects from conception to produc...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$180K *

Champion the paid funnel strategy to drive capital into our real estate vertical. Own the entire process from ad creation to investor engagement, ensuring a seamless transition to the investor relatio...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Business Services

$90K - $110K *

Champion client success by leading complex implementations, managing risks, and ensuring operational readiness. Collaborate with executive stakeholders to deliver projects on time while maintaining hi...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$80K - $100K *

Join us to drive rapid sales cycles and new customer acquisition in a dynamic, metrics-driven environment. You'll manage a robust pipeline, engage key stakeholders, and leverage digital tools to achie...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Information Technology

$110K - $125K *

Elevate your career by driving strategic sales initiatives in a dynamic environment. Leverage your expertise to build relationships, influence decision-makers, and expand market presence while managin...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $160K *

Join a dynamic team to lead large-scale NetSuite projects, enhancing client experiences through strategic project management and collaboration. Utilize your expertise in pre-sales and implementation t...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$84K - $135K *

Accelerate your career as you build key relationships and drive sales success in the construction supplies sector, achieving ambitious targets while supporting distributor partners in a dynamic field...

RemoteRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$125K - $150K *

Drive growth by hunting new logos and managing full-cycle enterprise deals across a 50-60-account territory. Collaborate with cross-functional teams to shape strategies and turn wins into repeatable m...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Drive the enhancement of Compliance Monitoring and Testing programs, ensuring regulatory alignment and effective risk management. Collaborate with stakeholders to improve operational efficiency and su...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$150K - $180K *

Lead the charge in optimizing marketing operations to drive developer adoption, pipeline growth, and revenue. Oversee systems, processes, and insights while collaborating with cross-functional teams t...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$163K - $261K *

Shape the future of electrification services by leading operations across the West U.S. region, driving performance excellence, and managing nationwide digital automation initiatives while advancing r...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$150K - $180K *

Champion enterprise data architecture by establishing standards and a unified data catalog. Collaborate across teams to define metrics and ensure data governance, driving alignment and clarity in a ha...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of jobs can I find in Mississippi on Ladders?question toggle

    You can explore professional opportunities across fields such as healthcare, finance, manufacturing, technology, energy, and business operations. Roles and availability vary over time.

  • Are Mississippi jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional jobs that pay $100,000 or more. Check each listing for compensation details, qualifications, and other job-specific information.

  • Where in Mississippi can I search for jobs?question toggle

    Search across the state, including employment centers such as Jackson, Gulfport, and Southaven. You can use location filters to narrow results.

  • How can I find remote or hybrid jobs based in Mississippi?question toggle

    Use available work-arrangement filters or review listing details to identify remote and hybrid opportunities. Availability depends on the employer and role.

  • How do I improve my chances of getting hired for a Mississippi job?question toggle

    Tailor your résumé to the role, emphasize relevant experience and measurable outcomes, and ensure you meet the listed qualifications before applying.