Discover professional opportunities across North Carolina with Ladders, a job site focused on roles paying $100,000 or more. From established business centers to growing regional markets, the state offers opportunities for experienced professionals seeking their next career move.
Charlotte is a major hub for banking, financial services, and corporate leadership. The Research Triangle—including Raleigh, Durham, and Chapel Hill—has opportunities across technology, life sciences, healthcare, education, and research. Other cities and regions also support careers in manufacturing, logistics, energy, and professional services.
Browse senior and specialized openings in areas such as software and technology, finance, healthcare, engineering, sales, operations, and executive leadership. Listings vary by employer and location, so review each posting for its responsibilities, qualifications, work arrangement, and compensation details.
Use Ladders to explore vetted professional jobs with salaries of $100,000 or more. Search by job title, employer, or location, and compare openings across North Carolina to find roles that align with your experience and career goals.
$143K - $198K *
Elevate your career by designing and maintaining robust enterprise network infrastructures. Collaborate with cross-functional teams to optimize performance, ensure security, and support critical appli...
Today
$75K - $129K *
Join a team that's redefining data solutions by architecting scalable data pipelines and cloud platforms. Leverage your expertise to deliver reliable data for strategic initiatives and operational exc...
6 days ago
$100K - $120K *
Join us to lead the full sales cycle of our innovative TMS system, driving growth in the mental health sector. Collaborate with founders, engage with clinical customers, and shape our market strategy...
2 weeks ago
$100K - $120K *
Drive business analysis by gathering requirements, documenting processes, and validating Salesforce solutions to enhance customer satisfaction and operational efficiency through effective stakeholder...
Reposted 2 weeks ago
Customer Advocacy Marketing Manager
$90K - $124K *
Unlock potential by leading customer advocacy initiatives, driving content strategy, and managing high-volume production of case studies and testimonials. Collaborate with cross-functional teams to en...
1 week ago
$83K - $114K *
Join our dynamic team as you deliver compassionate dialysis nursing services. Collaborate with professionals in a fast-paced environment, utilizing your critical thinking skills to ensure patient safe...
2 weeks ago
Women's Health- Full-Time- Certified Nurse Midwife
$114K - $171K *
Grow your career with a dynamic healthcare team focused on delivering comprehensive midwifery services in both inpatient and outpatient settings. Enjoy collaborative support while expanding your exper...
3 weeks ago
$125K - $150K *
Transform relationships with customers or partners by developing tailored sales plans and fostering trust, aimed at exceeding sales goals while acting as a thought leader in a fast-paced, complex envi...
3 weeks ago
$150K - $180K *
Transform the public sector sales landscape by leading a dynamic team to exceed targets, foster relationships, and drive growth through strategic engagement. Your expertise will empower success and in...
3 weeks ago
$62K - $100K *
Advance data analysis of health encounters to ensure compliance with SLAs while driving continuous process improvement. Collaborate across teams to enhance data usability and support regulatory initia...
2 weeks ago
Cons Prod Strategic Analyst IV - H4
$95K - $115K *
Unlock advanced analytics to drive strategic improvements in consumer products, ensuring high performance in risk and profitability through actionable insights and partnership across teams for optimal...
2 weeks ago
Senior Forward Deployed Engineer
$125K - $150K *
Engineer transformative solutions by integrating cutting-edge APIs into enterprise systems. Collaborate closely with clients to deploy production software efficiently while leveraging modern AI tools...
Reposted 2 weeks ago
$95K - $115K *
Shape operational excellence by leading a dynamic team in materials planning and execution for Engineered-to-Order manufacturing, ensuring timely delivery and optimal resource utilization while foster...
6 days ago
Sr. Director, Clinical Business Development
$180K - $258K *
Drive sales growth by strategizing expansion and nurturing key client relationships. Leverage data insights to optimize territory performance and collaborate with cross-functional teams to deliver tai...
2 weeks ago
Sr. Director, Clinical Business Development
$180K - $258K *
Advance business growth by driving strategic sales across regions, nurturing client partnerships, and orchestrating multi-functional solutions to enhance value and performance in the biopharmaceutical...
2 weeks ago
$80K - $95K *
Optimize property performance through strategic maintenance leadership, driving safety culture and sustainability. This impactful role necessitates technical expertise and frequent travel to ensure ex...
2 weeks ago
Project Manager II - NCCT Study Start-up Navigator
$68K - $103K *
Oversee the planning and execution of multi-center studies, ensuring compliance and successful outcomes. Collaborate with researchers, manage staff, and evaluate data to drive impactful health-related...
Today
Program Manager - Hub Operations
$90K - $110K *
Contribute to the success of pharmaceutical programs by managing client relationships, overseeing daily operations, and driving performance. Collaborate cross-functionally to ensure program execution...
Reposted 1 week ago
Registered Nurse (RN) - Maternity LDRP Float Pool
$79K - $118K *
Champion patient care by implementing evidence-based practices and collaborating with healthcare teams. Engage in continuous improvement initiatives while ensuring safety and effective communication w...
Reposted 3 weeks ago
Contract Lifecycle Management Consultant , Manager
$99K - $232K *
Advance your career by leading contract lifecycle management projects that drive innovation and optimize processes. You'll guide teams, enhance operations, and empower clients with data-driven solutio...
2 weeks ago
Contract Lifecycle Management Consultant , Manager
$99K - $232K *
Lead the charge in transforming contract lifecycle management to drive innovation and optimize processes. Leverage data analytics and technology to enhance client operations while mentoring teams and...
2 weeks ago
$100K - $120K *
Champion innovative sales strategies and drive B2B growth in the fintech sector. As a key team member, excel in consultative selling while building strong relationships and harnessing internal experti...
Reposted 2 weeks ago
Senior Solutions Architect, Pre-sales | Remote
$125K - $150K *
Accelerate solution design for scalable, cloud-based SaaS platforms, engaging with stakeholders to translate complex needs into actionable strategies while fostering innovation in higher education tec...
2 weeks ago
Application Clinical Analyst III
$82K - $114K *
Transform clinical applications by assessing needs, troubleshooting solutions, and implementing upgrades. Collaborate with teams to enhance workflows and provide expert support, ensuring optimal funct...
1 week ago
$90K - $110K *
Analyze and optimize workforce management strategies across multiple business lines, translating complex forecasts into actionable capacity plans and financial models while collaborating with executiv...
1 week ago
What types of $100K+ jobs can I find in North Carolina?
Listings may include senior and specialized roles in technology, finance, healthcare, engineering, sales, operations, and executive leadership. Available positions depend on current employer hiring needs.
Which North Carolina cities have professional job opportunities?
Opportunities can be found in Charlotte, Raleigh, Durham, Chapel Hill, and other North Carolina cities and regions. Search by location to see current openings.
Does Ladders list jobs paying $100,000 or more?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Check individual postings for compensation information and role details.
How can I search for jobs in North Carolina?
Search Ladders by job title, employer, or North Carolina location, then review listings for qualifications, responsibilities, work arrangement, and compensation.