Explore $100K+ Jobs in North Carolina

Discover professional opportunities across North Carolina with Ladders, a job site focused on roles paying $100,000 or more. From established business centers to growing regional markets, the state offers opportunities for experienced professionals seeking their next career move.

North Carolina’s Professional Job Markets

Charlotte is a major hub for banking, financial services, and corporate leadership. The Research Triangle—including Raleigh, Durham, and Chapel Hill—has opportunities across technology, life sciences, healthcare, education, and research. Other cities and regions also support careers in manufacturing, logistics, energy, and professional services.

Roles for Experienced Professionals

Browse senior and specialized openings in areas such as software and technology, finance, healthcare, engineering, sales, operations, and executive leadership. Listings vary by employer and location, so review each posting for its responsibilities, qualifications, work arrangement, and compensation details.

Find Your Next North Carolina Opportunity

Use Ladders to explore vetted professional jobs with salaries of $100,000 or more. Search by job title, employer, or location, and compare openings across North Carolina to find roles that align with your experience and career goals.

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$80K - $90K *

Transform the K-12 EdTech landscape by driving sales and building relationships with key district decision-makers. Own your territory, manage the sales lifecycle, and collaborate with a dynamic team t...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$146K - $233K *

Transform complex litigation management by coordinating legal teams, overseeing case operations, and enhancing client interactions. This senior-level role offers an opportunity to lead sophisticated c...

2 weeks ago

  •   8 - 10 years exp.  •   Staffing

$90K - $110K *

Drive technical solutions and client satisfaction as you partner with internal teams, enhancing client engagement through innovative use of our solutions, troubleshooting complex integrations, and fos...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$125K - $150K *

Lead strategic HR initiatives as a trusted advisor to executives, aligning workforce strategies with business goals. Drive organizational effectiveness, talent management, and change leadership to enh...

4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$80K - $95K *

Take ownership of strategic financial analyses and M&A activities to drive growth, evaluate investment opportunities, and support post-acquisition integration for organizational success and alignment...

2 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$88K - $105K *

Lead cross-functional initiatives in a regulated environment by coordinating project plans, tracking progress, and managing risks to ensure operational and inspection readiness for timely execution...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$88K - $105K *

Support our pricing strategy development by analyzing complex data and market trends. Collaborate with multiple teams to optimize profitability, improve processes, and present insights to management i...

2 weeks ago

  •   Less than 5 years exp.  •   Transportation

$100K - $120K *

Transform regional operations by leading P&L performance, ensuring compliance, and optimizing service delivery across multiple data center facilities while driving safety standards and customer satisf...

3 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$83K - $125K *

Drive sales by developing relationships and supporting RVPs to enhance Transamerica's market presence in mutual funds, annuities, and insurance, ensuring proactive and responsive interactions that yie...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$115K - $150K *

Join a team that's shaping the future of residential credit trading. As an Analyst, you will engage in strategic sourcing, optimize financial operations, and enhance analytical reporting within a dyna...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$122K - $183K *

Manage and optimize global equity compensation programs, ensuring accurate transactions, compliance, and enhanced employee experience while collaborating with cross-functional teams to streamline oper...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$80K - $95K *

Transform sales strategies and elevate client relationships by engaging healthcare professionals in your territory to boost product loyalty and foster brand growth through data-driven insights and tai...

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$113K - $170K *

Lead the charge in transforming customer integrations by driving technical discovery, scoping complex implementations, and ensuring successful onboarding for high-stakes accounts. Collaborate closely...

US-AnywhereRemote

Today

  •   Less than 5 years exp.  •   Enterprise Technology

$125K - $150K *

Grow your career with a dynamic sales leadership role, driving team success and implementing best practices to exceed quotas in a thriving cybersecurity environment. Lead, mentor, and strategize to ex...

5 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $130K *

Advance your career by driving software adoption and revenue growth within existing client accounts. Collaborate closely with diverse teams to develop strategic plans, strengthen relationships, and de...

US-AnywhereRemote

4 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$85K - $100K *

Unlock financial excellence as a Senior Analyst in FP&A, driving corporate budgeting, forecasting, and cash flow visibility. Collaborate with leaders across functions, ensuring timely reporting and an...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$90K - $128K *

Pioneer mainframe engineering excellence by enhancing z/OS systems. Collaborate with teams to ensure optimal performance, serve as Scrum Master, and drive Agile initiatives for continuous improvement...

US-AnywhereRemote

5 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$140K - $175K *

Drive strategic initiatives for untouched enterprise accounts, crafting entry strategies while enhancing live deals. Collaborate with executives to build significant value and deliver tangible results...

US-AnywhereRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Lead the strategic direction of high-value client accounts, ensuring alignment with business objectives and driving growth through trusted partnerships and effective team leadership...

US-AnywhereRemote

4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Empower organizational success by aligning HR strategies with executive goals. Drive talent development, workforce planning, and sustainable change initiatives while leveraging analytics and AI to enh...

4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$112K - $222K *

Champion clinical excellence by leading site management teams throughout trial phases, ensuring compliance and outstanding patient care. Play a critical role in driving scientific advancements within...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $100K *

Champion the social media landscape by managing content, engagement, and analytics across multiple brands. Drive strategic initiatives, enhance community interaction, and elevate brand narratives in a...

US-AnywhereRemote

Today

  •   Less than 5 years exp.  •   Business Services

$120K - $150K *

Accelerate growth by shaping innovative marketing strategies for consumer products. Lead brand development, community engagement, and performance marketing initiatives to make blockchain accessible an...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$80K - $135K *

Lead the charge in providing strategic project management services for state HHS agencies, ensuring timely and quality deliverables while inspiring project teams and fostering client relationships acr...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Legal & Accounting

$235K - $315K *

Join a mission-driven team to drive growth within law enforcement and first responder agencies. Utilize your unique background to build relationships, close deals, and expand accounts in a high-perfor...

US-AnywhereRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    Listings may include senior and specialized roles in technology, finance, healthcare, engineering, sales, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Which North Carolina cities have professional job opportunities?question toggle

    Opportunities can be found in Charlotte, Raleigh, Durham, Chapel Hill, and other North Carolina cities and regions. Search by location to see current openings.

  • Does Ladders list jobs paying $100,000 or more?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Check individual postings for compensation information and role details.

  • How can I search for jobs in North Carolina?question toggle

    Search Ladders by job title, employer, or North Carolina location, then review listings for qualifications, responsibilities, work arrangement, and compensation.