Explore $100K+ Jobs in North Carolina

Discover professional opportunities across North Carolina with Ladders, a job site focused on roles paying $100,000 or more. From established business centers to growing regional markets, the state offers opportunities for experienced professionals seeking their next career move.

North Carolina’s Professional Job Markets

Charlotte is a major hub for banking, financial services, and corporate leadership. The Research Triangle—including Raleigh, Durham, and Chapel Hill—has opportunities across technology, life sciences, healthcare, education, and research. Other cities and regions also support careers in manufacturing, logistics, energy, and professional services.

Roles for Experienced Professionals

Browse senior and specialized openings in areas such as software and technology, finance, healthcare, engineering, sales, operations, and executive leadership. Listings vary by employer and location, so review each posting for its responsibilities, qualifications, work arrangement, and compensation details.

Find Your Next North Carolina Opportunity

Use Ladders to explore vetted professional jobs with salaries of $100,000 or more. Search by job title, employer, or location, and compare openings across North Carolina to find roles that align with your experience and career goals.

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$150K - $235K *

Elevate your legal career by delivering strategic counsel and effective services to Managed Services Organizations and physician practices, while managing complex legal projects and mentoring a team i...

US-AnywhereRemote

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$95K - $140K *

Drive strategic business management initiatives by analyzing metrics, supporting leaders, and implementing process improvements to enhance operational efficiency and achieve business objectives...

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$96K - $120K *

Join a dynamic team to manage Payroll and Time Tracking system enhancements, document specifications, analyze HR data, support stakeholders, and improve processes while collaborating across HR functio...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Join our dynamic legal team to support contract negotiations, manage legal processes, and provide guidance on commercial agreements. Leverage your expertise to enhance efficiencies and navigate comple...

US-AnywhereRemote

4 days ago

  •   Less than 5 years exp.  •   Legal & Accounting

$105K *

Advance social media strategy across multiple properties, driving organic engagement and performance through collaboration and innovative tools. Manage content flow, oversee day-to-day operations, and...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$130K - $160K *

Join us to architect and scale robust backend systems for a real-time AI voice platform, enhancing healthcare accessibility through innovative microservices and secure integrations with EHR systems wh...

US-AnywhereRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$88K - $145K *

Join our dynamic sales team to drive results through effective outreach, pipeline management, and collaboration. Embrace a fast-paced environment where your contributions directly impact success and g...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$114K - $171K *

Lead comprehensive health assessments and develop tailored care plans in collaboration with a multidisciplinary team. Manage patient care protocols, ensuring early identification of issues while suppo...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Join us as a hands-on strategist managing client accounts and Meta campaigns. You'll drive performance, foster strong relationships, and translate data into actionable recommendations while ensuring c...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$90K - $110K *

Transform customer engagement by delivering tailored product demonstrations, guiding technical discussions, and architecting solutions that meet unique educational needs across diverse sectors...

US-AnywhereRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$90K - $110K *

Join our dynamic team to shape transformational learning solutions that empower commercial teams, enhance client experiences, and drive organizational growth through innovative training strategies and...

US-AnywhereRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$135K - $159K *

Champion privacy excellence by leading assessments and driving compliance across products. Collaborate with cross-functional teams to enhance frameworks, streamline processes, and ensure customer data...

US-AnywhereRemote

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$100K - $180K *

Partner with leaders to drive strategy and impact as a key financial advisor, overseeing budgeting, forecasting, and strategic planning. Collaborate with executives and business units to provide insig...

US-AnywhereRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$88K - $132K *

Elevate healthcare accuracy by enhancing outpatient clinical documentation, coding, and charging processes. Collaborate with clinical departments to ensure compliance while driving educational initiat...

US-AnywhereRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $200K *

Join a team that's focused on driving growth and expanding market presence. This role requires a proactive sales professional to identify new opportunities, manage relationships, and deliver measurabl...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Join a team that shapes the people vision and delivers strategic HR support across the employee lifecycle, guiding a small team in an innovative AI-native environment while coaching leaders to enhance...

US-AnywhereRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$88K - $121K *

Support U.S. government clients by troubleshooting and enhancing search experiences using Lucidworks Fusion, collaborating across teams to resolve issues and improve product offerings while providing...

US-AnywhereRemote

4 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $95K *

Champion seamless communication by managing VoIP and telephony systems, ensuring optimal performance and user satisfaction. Collaborate across departments to analyze data, enhance workflows, and uphol...

US-AnywhereRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $110K *

Empower your career by delivering innovative Smart Communications solutions. Manage projects remotely, ensuring timely, budget-friendly implementations while achieving high client satisfaction and col...

US-AnywhereRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Champion the functional implementation of our rental management solution, guiding clients through discovery, configuration, and go-live phases to ensure successful deployments that enhance operational...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Staffing

$120K - $145K *

Join a dynamic team to lead technical pre-sales engagements, translating advanced AI solutions into impactful business outcomes for enterprise clients. Collaborate closely with sales and engineering t...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $160K *

Drive the strategic evolution and governance of equity compensation programs in a dynamic private equity context. Lead vendor management, execute precise equity agreements, and ensure compliance while...

US-AnywhereRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$114K - $191K *

Lead the charge in shaping high-impact SaaS solutions by driving technical strategy and empowering a high-performing engineering team. Collaborate across disciplines to foster innovation in a fast-pac...

US-AnywhereRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$90K - $178K *

Lead the charge in enhancing patient engagement by shaping strategic patient and site support initiatives, ensuring study participation barriers are identified and mitigated while fostering collaborat...

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$90K - $178K *

Transform the patient engagement landscape in clinical trials by developing and delivering strategic support initiatives. Partner with diverse stakeholders to enhance participation and optimize patien...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    Listings may include senior and specialized roles in technology, finance, healthcare, engineering, sales, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Which North Carolina cities have professional job opportunities?question toggle

    Opportunities can be found in Charlotte, Raleigh, Durham, Chapel Hill, and other North Carolina cities and regions. Search by location to see current openings.

  • Does Ladders list jobs paying $100,000 or more?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Check individual postings for compensation information and role details.

  • How can I search for jobs in North Carolina?question toggle

    Search Ladders by job title, employer, or North Carolina location, then review listings for qualifications, responsibilities, work arrangement, and compensation.