Discover professional opportunities across North Carolina with Ladders, a job site focused on roles paying $100,000 or more. From established business centers to growing regional markets, the state offers opportunities for experienced professionals seeking their next career move.
Charlotte is a major hub for banking, financial services, and corporate leadership. The Research Triangle—including Raleigh, Durham, and Chapel Hill—has opportunities across technology, life sciences, healthcare, education, and research. Other cities and regions also support careers in manufacturing, logistics, energy, and professional services.
Browse senior and specialized openings in areas such as software and technology, finance, healthcare, engineering, sales, operations, and executive leadership. Listings vary by employer and location, so review each posting for its responsibilities, qualifications, work arrangement, and compensation details.
Use Ladders to explore vetted professional jobs with salaries of $100,000 or more. Search by job title, employer, or location, and compare openings across North Carolina to find roles that align with your experience and career goals.
$150K - $180K *
Champion portfolio-level construction delivery for 3-5 data centers, ensuring on-time, on-budget execution while managing risk across multiple sites. Partner with teams to drive success in a high-grow...
Reposted 1 week ago
$110K - $130K *
Unlock potential by leading complex projects and implementations in cloud-based procurement solutions. Collaborate with cross-functional teams to deliver innovative designs and ensure stakeholder sati...
2 weeks ago
Regional Vice President - Retirement Mid Markets (Ohio/Kentucky)
$90K - $100K *
Accelerate your career by driving retirement plan sales across diverse markets. Build strong relationships with financial intermediaries and manage your territory effectively to achieve ambitious sale...
2 weeks ago
Sr. Reimbursement Analyst (Ops) - Remote
$101K - $152K *
Unlock your potential by supporting reimbursement operations and strategic initiatives that enhance patient access across diverse therapies. Collaborate with cross-functional teams to drive process im...
4 days ago
Clinical Pharmacist, Acute Care Pharmacy, Hybrid, Hospital at Home and Internal Medicine
$114K - $171K *
Join a collaborative team to deliver patient-centered pharmaceutical care in acute internal medicine, enhance therapeutic outcomes, and educate healthcare professionals, all while contributing to inno...
Reposted 5 days ago
General Manager, Collibra Public Sector
$160K - $200K *
Lead the charge in executing strategic initiatives for a public sector subsidiary to ensure profitable growth, optimizing team performance, and aligning operations with government mandates and market...
4 weeks ago
Principal Enterprise-Wide Applications Analyst
$94K - $141K *
Shape the future of supply chain technology by driving enhancements and support for SAP S/4 functionalities, collaborating with diverse teams to implement strategic solutions that improve efficiency a...
Reposted today
$113K - $276K *
Explore the transition and stabilization of SAP BW applications, ensuring effective data modeling and reporting across finance and supply chain. Collaborate globally to maintain performance and compli...
5 days ago
Senior Salesforce Administrator
$100K - $115K *
Help us optimize our Salesforce platform by enhancing automation, ensuring system reliability, and driving high-impact initiatives that align with organizational goals while collaborating with stakeho...
1 week ago
$110K - $130K *
Lead the charge in shaping our compensation strategy by executing and evolving programs across global offers, market pricing, and salary structures, ensuring clarity and defensibility in compensation...
Reposted 3 weeks ago
$90K - $144K *
Transform post-award financial administration by leading teams, ensuring compliance, and optimizing processes. Drive strategic direction and enhance organizational capabilities to support growth in sp...
6 days ago
$90K - $144K *
Champion post-award financial administration, leading teams to enhance sponsored research. Drive compliance, optimize processes, and ensure effective management of grants and clinical trials while col...
6 days ago
$110K - $130K *
Lead the charge in developing and executing integrated project delivery within complex nuclear environments, ensuring compliance with safety, quality, and regulatory standards while managing interdisc...
Reposted today
$68K - $103K *
Transform patient care by performing CT scans, ensuring quality imaging, and assisting in procedures while adhering to safety protocols and providing exceptional support to patients and medical staff...
5 days ago
$156K - $164K *
Transform user engagement through multi-channel CRM strategies, driving onboarding, retention, and growth by collaborating across teams to optimize performance globally...
1 week ago
$200K *
Lead the charge in building and scaling AI Data Operations, transforming emerging opportunities into commercially viable solutions. Drive strategy, partnerships, and operational excellence to support...
1 week ago
$100K - $120K *
Join a team that's pioneering AI-driven identity solutions in the mid-market. You'll manage the full sales cycle, driving growth and cultivating lasting customer relationships while navigating complex...
Reposted 2 weeks ago
Account Executive - Splunk (Southeast)
$259K - $351K *
Lead the charge in driving revenue growth across enterprise accounts, building pipelines, and achieving sales targets. Collaborate with diverse stakeholders to expand relationships and orchestrate com...
1 week ago
Staff / Staff II - Application Security Engineer
$220K - $270K *
Unlock potential by guiding application security strategies across diverse product landscapes. In this senior technical role, you'll influence architecture, mentor teams, and enhance security processe...
2 weeks ago
Registered Nurse (RN) Medical Surgical Telemetry
$79K - $118K *
Join a team that's dedicated to delivering compassionate, comprehensive patient care in a fast-paced medical surgical telemetry unit, utilizing evidence-based practices to enhance patient experiences...
6 days ago
$90K - $100K *
Join a team that's shaping the future of automated testing by optimizing HyperExecute configurations and enhancing test execution across diverse environments. Collaborate with cross-functional teams t...
5 days ago
$150K - $279K *
Empower government sector success by identifying sales opportunities and leveraging legal tech expertise. Join a dynamic team to boost revenue through strategic outreach and relationship building whil...
2 weeks ago
Registered Nurse (RN) - ICU Float Pool
$79K - $118K *
Manage patient care by applying evidence-based practices while collaborating with a multidisciplinary team. Uphold safety standards and deliver quality outcomes in a fast-paced environment, while floa...
Reposted 3 weeks ago
Registered Nurse (RN) - ICU Float Pool
$79K - $118K *
Join a dynamic healthcare team as you deliver critical care across multiple units. This role offers diverse experiences, professional growth, and collaboration with interdisciplinary teams, all while...
4 weeks ago
Regional Vice President - Retirement Mid Markets (KY, NJ, NY, WA)
$90K - $100K *
Lead market growth by driving sales of retirement plans to small and mid-sized firms. Build partnerships, manage key relationships, and participate in marketing initiatives within a designated territo...
2 weeks ago
What types of $100K+ jobs can I find in North Carolina?
Listings may include senior and specialized roles in technology, finance, healthcare, engineering, sales, operations, and executive leadership. Available positions depend on current employer hiring needs.
Which North Carolina cities have professional job opportunities?
Opportunities can be found in Charlotte, Raleigh, Durham, Chapel Hill, and other North Carolina cities and regions. Search by location to see current openings.
Does Ladders list jobs paying $100,000 or more?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Check individual postings for compensation information and role details.
How can I search for jobs in North Carolina?
Search Ladders by job title, employer, or North Carolina location, then review listings for qualifications, responsibilities, work arrangement, and compensation.