Explore $100K+ Jobs in North Carolina

Discover professional opportunities across North Carolina with Ladders, a job site focused on roles paying $100,000 or more. From established business centers to growing regional markets, the state offers opportunities for experienced professionals seeking their next career move.

North Carolina’s Professional Job Markets

Charlotte is a major hub for banking, financial services, and corporate leadership. The Research Triangle—including Raleigh, Durham, and Chapel Hill—has opportunities across technology, life sciences, healthcare, education, and research. Other cities and regions also support careers in manufacturing, logistics, energy, and professional services.

Roles for Experienced Professionals

Browse senior and specialized openings in areas such as software and technology, finance, healthcare, engineering, sales, operations, and executive leadership. Listings vary by employer and location, so review each posting for its responsibilities, qualifications, work arrangement, and compensation details.

Find Your Next North Carolina Opportunity

Use Ladders to explore vetted professional jobs with salaries of $100,000 or more. Search by job title, employer, or location, and compare openings across North Carolina to find roles that align with your experience and career goals.

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$200K - $250K *

Join a team that builds accurate construction cost estimates from concept to completion. Collaborate with project managers and clients to ensure financial integrity and optimize project efficiencies w...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$175K - $195K *

Shape the future of global HR operations by enhancing systems and processes for a seamless employee lifecycle. Collaborate cross-functionally to improve workflows, compliance, and service effectivenes...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$102K - $177K *

Partner with us to lead a dynamic Customer Service team, ensuring efficient revenue recognition and issue resolution. Drive performance metrics, enhance customer experience, and collaborate across fun...

US-AnywhereRemote

5 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $115K *

Grow your career with a dynamic team driving innovative strategies and customer engagement. Leverage your sales expertise to enhance product visibility and exceed business goals in a supportive, colla...

US-AnywhereRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$100K - $120K *

Lead the charge in enterprise sales, driving new business in regulated industries. Develop strategic relationships, manage complex sales cycles, and collaborate with cross-functional teams to shape gr...

US-AnywhereRemote

Today

  •   Less than 5 years exp.  •   Business Services

$91K - $99K *

Join a team that's dedicated to enhancing HR processes and operational excellence. This role involves managing projects, leveraging data insights, and supporting HR initiatives to ensure consistent se...

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$95K - $115K *

Join a dynamic team to shape and scale a global customer advocacy program, driving impactful customer stories and insights that enhance market leadership and accelerate AI adoption across the customer...

6 days ago

  •   Less than 5 years exp.  •   Information Technology

$164K - $314K *

Shape the future of HR by leading strategic integration and planning initiatives. Drive alignment across functions, enhance operational effectiveness, and ensure scalable solutions that deliver measur...

Reposted 5 days ago

  •   11 - 15 years exp.  •   Finance & Insurance

$220K - $320K *

Shape the future of fund structuring and regulatory compliance by leading the development of legal frameworks and strategic partnerships that empower GPs to thrive in a complex market environment...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$79K - $118K *

Elevate patient care through hands-on Physical Therapy in an acute inpatient setting. Collaborate with a team to develop individualized treatment plans, document progress, and ensure optimal recovery...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $105K *

Join a team that's driving success through expert logistics management for large-scale events. Lead strategic planning and execution while fostering collaboration and mentorship, ensuring seamless coo...

2 weeks ago

  •   Less than 5 years exp.  •   Staffing

$110K - $130K *

Lead the charge in developing a sophisticated healthcare SaaS platform by designing, implementing, and maintaining full-stack features that enhance user experience and system performance in a dynamic...

US-AnywhereRemote

6 days ago

  •   5 - 7 years exp.  •   Staffing

$120K - $150K *

Drive HRIS excellence by optimizing technologies and core processes, enhancing compliance, and delivering impactful solutions that elevate operational efficiency and employee experience across the org...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$110K - $130K *

Engage with key clients to drive revenue growth by managing a dynamic sales pipeline, presenting solutions, and closing deals. Utilize expertise in eCommerce to innovate sales strategies and achieve a...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Collaborate in a high-growth, cross-functional role to transform ambiguous challenges into strategic outcomes, driving key initiatives that propel company growth and operational excellence...

US-AnywhereRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$116K - $149K *

Reimagine product marketing for partnerships by crafting compelling narratives and executing go-to-market strategies. Collaborate cross-functionally to enhance customer experiences and drive successfu...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$72K - $113K *

Deliver impactful insights by owning our marketing tech ecosystem, maximizing HubSpot and Salesforce integration, and ensuring data integrity. Collaborate across teams to translate needs into actions...

US-AnywhereRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Information Technology

$90K - $151K *

Join a team that's redefining cybersecurity governance by leading enterprise-level security programs. Enhance operational efficiency through automation while collaborating across teams to deliver acti...

Reposted 5 days ago

  •   Less than 5 years exp.  •   Business Services

$325K - $412K *

Join a team that's driving growth in enterprise software solutions. Lead high-performing sales teams, achieve revenue targets, and foster strong business partnerships while navigating a fast-paced env...

6 days ago

  •   8 - 10 years exp.  •   Telecommunications & Hardware

$325K - $412K *

Unlock your potential by leading high-performing sales teams to drive growth in enterprise software solutions. This role focuses on achieving revenue targets, mentoring talent, and fostering strong bu...

US-AnywhereRemote

6 days ago

  •   8 - 10 years exp.  •   Telecommunications & Hardware

$110K - $130K *

Transform global payroll operations across US, India, and UK. Elevate compliance, accuracy, and efficiency while managing an offshore team and collaborating with cross-functional stakeholders to strea...

US-AnywhereRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Media

$166K - $195K *

Elevate the external reporting process by owning SEC filings, driving improvements, and collaborating cross-functionally to ensure timely, accurate disclosures in a dynamic public company environment...

US-AnywhereRemote

Today

  •   8 - 10 years exp.  •   Finance & Insurance

$75K - $90K *

Lead impactful proposal and communication strategies, partnering with sales teams to deliver compelling RFP responses, optimize materials, and support business pursuits for effective client engagement...

US-AnywhereRemote

Reposted today

  •   Less than 5 years exp.  •   Transportation

$150K - $180K *

Drive new-client acquisition by managing the full sales cycle, from prospecting to contract signing. Collaborate with marketing and commercial teams to deliver tailored solutions and build executive r...

US-AnywhereRemote

Today

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$90K - $105K *

Analyze data and create actionable insights to enhance business intelligence. Engage in SQL, Python, and data visualization to maintain dashboards, support modeling, and drive improvements in efficien...

US-AnywhereRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Real Estate & Construction

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    Listings may include senior and specialized roles in technology, finance, healthcare, engineering, sales, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Which North Carolina cities have professional job opportunities?question toggle

    Opportunities can be found in Charlotte, Raleigh, Durham, Chapel Hill, and other North Carolina cities and regions. Search by location to see current openings.

  • Does Ladders list jobs paying $100,000 or more?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Check individual postings for compensation information and role details.

  • How can I search for jobs in North Carolina?question toggle

    Search Ladders by job title, employer, or North Carolina location, then review listings for qualifications, responsibilities, work arrangement, and compensation.