Explore $100K+ Jobs in North Carolina

Discover professional opportunities across North Carolina with Ladders, a job site focused on roles paying $100,000 or more. From established business centers to growing regional markets, the state offers opportunities for experienced professionals seeking their next career move.

North Carolina’s Professional Job Markets

Charlotte is a major hub for banking, financial services, and corporate leadership. The Research Triangle—including Raleigh, Durham, and Chapel Hill—has opportunities across technology, life sciences, healthcare, education, and research. Other cities and regions also support careers in manufacturing, logistics, energy, and professional services.

Roles for Experienced Professionals

Browse senior and specialized openings in areas such as software and technology, finance, healthcare, engineering, sales, operations, and executive leadership. Listings vary by employer and location, so review each posting for its responsibilities, qualifications, work arrangement, and compensation details.

Find Your Next North Carolina Opportunity

Use Ladders to explore vetted professional jobs with salaries of $100,000 or more. Search by job title, employer, or location, and compare openings across North Carolina to find roles that align with your experience and career goals.

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$150K - $180K *

Unlock potential by leading enterprise sales initiatives, managing complex accounts, and driving strategic growth. You will navigate technical discussions and deliver value-driven solutions to top-tie...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $155K *

Accelerate progress at the forefront of business development in custom adhesive solutions, driving growth across North America’s Bus, Truck, Rail, and Specialty Vehicle markets while fostering strong...

Today

  •   8 - 10 years exp.  •   Business Services

$110K - $130K *

Drive enterprise sales by managing the full cycle from prospecting to closing, building relationships with executive stakeholders, and delivering impactful business cases to secure multi-year agreemen...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Transportation

$120K - $155K *

Champion business development and growth of custom adhesive solutions across North America, focusing on the Bus, Truck, Rail, and Specialty Vehicle markets. Drive customer acquisition and strategic ac...

US-AnywhereRemote

Today

  •   8 - 10 years exp.  •   Business Services

$116K - $178K *

Join us in supporting our rapid growth by providing legal expertise in contract negotiations and management. Collaborate with teams across the Americas to ensure compliance and drive revenue while mai...

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$79K - $118K *

Join a dedicated team in providing exceptional care in Labor and Delivery. This role involves coordinating comprehensive patient care, ensuring safety and therapeutic practices for mothers and newborn...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Join our dynamic team as you drive accurate commission management, streamline processes, and shape incentive plans in a fast-paced GTM organization. Leverage your expertise to resolve disputes and enh...

US-AnywhereRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Transform your career by leading a remote team in Disability Claims Management. Oversee investigations, manage claims, and drive success while ensuring compliance and timely resolutions. Make a meanin...

US-AnywhereRemote

2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$243K - $286K *

Champion a transformative approach in Developer Infrastructure, defining strategy and vision for the code lifecycle. Enhance engineer productivity through innovative tools and reliable systems while e...

US-AnywhereRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$136K - $226K *

Shape the future of regional payroll services by leading delivery teams, ensuring compliance, and optimizing efficiency across payroll and time attendance processes while managing critical projects an...

US-AnywhereRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$114K - $171K *

Unlock potential by leading strategic program management, fostering collaboration, and implementing best practices that enhance organizational effectiveness while ensuring adherence to compliance and...

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$114K - $171K *

Unlock your potential by leading a key program that drives strategic goals, fostering collaboration and ensuring effective operations. Manage projects and enhance outcomes while supporting a skilled t...

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $200K *

Accelerate progress at a dynamic SaaS company, driving full-cycle sales from prospecting to closing in a high-impact role. Design foundational sales materials and processes that empower future success...

4 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$79K - $118K *

Join a team that's dedicated to improving patient outcomes through evidence-based nursing care. Engage with patients, families, and a collaborative care team across various units while promoting a cul...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$73K - $110K *

Lead the charge in delivering exceptional oncology care through patient assessments, treatment planning, and coordination of infusion therapies in a supportive practice environment. Collaborate with p...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$77K - $85K *

Collaborate effectively to optimize procurement strategies, ensuring best value for money across corporate and care center operations while managing vendor relationships and facilitating contract appr...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $125K *

Accelerate progress at building strategic relationships with CPG sales organizations, driving innovative commercial models and data strategies to enhance revenue growth and client satisfaction in a dy...

US-AnywhereRemote

Today

  •   Less than 5 years exp.  •   Business Services

$100K - $125K *

Pioneer impactful relationships with CPG sales teams to drive growth through innovative strategies, operational excellence, and cross-functional collaboration, ultimately enhancing client satisfaction...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$100K - $125K *

Transform client engagement by cultivating strategic relationships and driving innovative go-to-market strategies that enhance revenue growth and operational excellence across the Healthcare sector...

US-AnywhereRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Business Services

$100K - $125K *

Advance business growth by fostering relationships and crafting innovative strategies that drive revenue. Collaborate across teams to identify opportunities and enhance operational excellence while en...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Business Services

$109K - $141K *

Take ownership of enhancing pre-litigation operations by leading case managers, streamlining workflows, and ensuring compliance while fostering a high-performing team culture dedicated to quality and...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Legal & Accounting

$74K - $118K *

Transform your career by leading impactful contract initiatives and ensuring compliance within a dynamic healthcare environment. Collaborate cross-functionally to optimize provider relationships and c...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$79K - $118K *

Empower patient care as a dynamic RN in a float pool environment. Collaborate across units, delivering high-quality nursing for diverse patient populations while maintaining safety and adherence to be...

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Join a team that's redefining healthcare sales by mastering complex deals and building relationships with C-level executives. Enhance your career through mentorship and collaboration while impacting p...

US-AnywhereRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Advance your career with this senior role focused on enhancing cybersecurity for manufacturing operations. Collaborate with diverse teams to implement solutions that protect critical systems while mai...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    Listings may include senior and specialized roles in technology, finance, healthcare, engineering, sales, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Which North Carolina cities have professional job opportunities?question toggle

    Opportunities can be found in Charlotte, Raleigh, Durham, Chapel Hill, and other North Carolina cities and regions. Search by location to see current openings.

  • Does Ladders list jobs paying $100,000 or more?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Check individual postings for compensation information and role details.

  • How can I search for jobs in North Carolina?question toggle

    Search Ladders by job title, employer, or North Carolina location, then review listings for qualifications, responsibilities, work arrangement, and compensation.