Explore $100K+ Jobs in California

Discover professional opportunities across California with Ladders. From established business centers to growing regional economies, the state offers senior-level roles in technology, healthcare, finance, entertainment, manufacturing, and more. Browse vetted job listings with salaries of $100,000 or higher and find positions that align with your experience and career goals.

California industries and career opportunities

California’s diverse economy supports leadership and specialized roles at companies of all sizes. Depending on your background, you may find opportunities in software and technology, life sciences, healthcare, financial services, clean energy, media, aerospace, and professional services. Job availability and compensation vary by role, employer, and location.

Find jobs throughout the state

Explore openings in major employment centers such as Los Angeles, San Francisco, San Diego, San Jose, Sacramento, and surrounding communities. Listings may include on-site, hybrid, and remote arrangements; review each posting for its work location and requirements.

Search with Ladders

Use Ladders to focus your search on vetted professional jobs paying $100,000 or more. Review role responsibilities, qualifications, compensation details, and workplace expectations, then apply directly to opportunities that fit your goals. Keep your profile and resume current so employers can better understand your experience.

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1,000+

Jobs in California

Average Salary in USD

Average Salary: $142,597

Sort By: Relevance

$135K - $160K *

Lead a dynamic team to transform AI strategies into impactful healthcare solutions. Oversee engineering execution, guide architecture, and ensure compliance while collaborating with cross-functional p...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Healthcare

$93K - $120K *

Help us advance student wellness by providing clinical case management and support. Collaborate with diverse stakeholders to enhance mental health services and promote inclusive excellence within the...

Reposted today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$88K - $92K *

Lead the charge in advancing winds performance education through innovative teaching, mentorship, and collaboration. Shape the future of aspiring musicians while contributing to a vibrant artistic com...

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$228K - $342K *

Empower your career by leading strategic project management initiatives across early drug development. Drive process optimization, cultivate high-performing teams, and collaborate with executives to a...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Lead the charge in optimizing revenue cycle operations, ensuring compliance and efficiency across Prior Authorization and Medical Billing teams while driving measurable improvements in performance and...

Today

  •   5 - 7 years exp.  •   Healthcare

$125K - $150K *

Lead the charge in innovative AI solutions, driving impactful projects with a small, agile team. Collaborate across disciplines to tackle complex challenges and deliver exceptional results in a fast-p...

Today

  •   Less than 5 years exp.  •   Information Technology

$88K - $92K *

Transform the future of winds performance by leading innovative teaching and mentoring in a dynamic music department. Engage with diverse students and contribute to artistic excellence while maintaini...

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$86K - $88K *

Join a team that's dedicated to enhancing donor relationships and expanding equity-focused programming. Play a key role in developing strategies to secure corporate and foundation support, ensuring di...

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$124K - $158K *

Elevate patient care by conducting comprehensive medication reviews and consultations. Collaborate with prescribers to optimize therapy, enhance adherence, and improve health outcomes in a remote, pat...

Today

  •   Less than 5 years exp.  •   Healthcare

$118K - $166K *

Join a team that's dedicated to enhancing critical water and wastewater systems. Lead a specialized group in maintaining process control technologies, ensuring cybersecurity, and collaborating with di...

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$150K - $180K *

Lead the charge in expanding our global Advisory business by driving business development, overseeing project delivery, and mentoring a diverse team of consultants to address complex client challenges...

Today

  •   8 - 10 years exp.  •   Real Estate & Construction

$100K - $110K *

Advance your career by conducting vital physical security evaluations across multiple data centers. Collaborate with teams to enhance security measures and protect critical infrastructure while engagi...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$392K - $450K *

Drive the strategic direction of the Neurology Clinical Development team, overseeing clinical programs and lifecycle management to ensure innovative treatments reach patients effectively and efficient...

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$85K - $102K *

Empower your career by leading a dynamic team to deliver exceptional guest experiences while driving operational excellence and achieving sales targets in a fast-paced retail environment...

Today

  •   Less than 5 years exp.  •   Food & Beverages

$236K - $308K *

Accelerate growth by leading complex sales cycles and expanding Cisco's portfolio within high-value aerospace environments. Collaborate with a dynamic team to drive innovation and deliver secure netwo...

Today

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$130K - $145K *

Drive your career with impactful project management, overseeing renovations and repairs for critical public safety departments. Ensure successful project delivery through collaboration, budget managem...

Today

  •   5 - 7 years exp.  •   Real Estate & Construction

$144K - $192K *

Manage end-to-end supply chain processes, integrating demand forecasts and production schedules to ensure timely delivery while balancing service, inventory, and supply risks. Lead cross-functional te...

Today

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$106K - $181K *

Join our team to execute R&D manufacturing projects, leveraging your expertise in sheet metal processes and engineering to enhance production readiness for critical programs in a dynamic environment...

Today

  •   5 - 7 years exp.  •   Aerospace & Defense

$135K - $160K *

Drive innovation by architecting and building a real-time ground data pipeline for aircraft telemetry, ensuring low latency and high reliability in a dynamic startup environment. Your work will direct...

Today

  •   5 - 7 years exp.  •   Aerospace & Defense

$95K - $115K *

Join a team that's redefining product marketing by driving impactful go-to-market strategies, enabling sales teams, and translating complex product features into clear customer value across diverse ma...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$90K - $120K *

Join a dynamic team to coordinate MEP systems across diverse projects, ensuring quality and compliance while driving collaboration among stakeholders to resolve issues and maintain schedules throughou...

Reposted today

  •   Less than 5 years exp.  •   Real Estate & Construction

$130K - $160K *

Champion the development of innovative products by leveraging full-stack engineering skills. Collaborate with clinicians and teammates to transform complex challenges into user-friendly solutions, dri...

Today

  •   Less than 5 years exp.  •   Healthcare

$71K - $116K *

Elevate your career by supporting senior executives in a dynamic environment. This role involves managing office operations, facilitating collaboration, and ensuring compliance while enhancing organiz...

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$156K - $202K *

Lead the charge in enhancing patient safety through innovative programs and data-driven strategies. Collaborate with cross-functional teams to improve care outcomes and operational efficiency while en...

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$118K - $224K *

Deliver innovative mechanical designs for Opto-Mechanical Assemblies, collaborating with cross-functional teams to optimize performance and cost. Utilize advanced CAD tools and ensure compliance with...

Today

  •   8 - 10 years exp.  •   Aerospace & Defense

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in California?question toggle

    California listings may include senior and specialized roles in technology, healthcare, finance, life sciences, entertainment, clean energy, manufacturing, and other fields. Available positions depend on current employer needs.

  • Where in California can I search for jobs?question toggle

    You can explore opportunities across the state, including major employment hubs such as Los Angeles, San Francisco, San Diego, San Jose, and Sacramento. Check each posting for its specific location and work arrangement.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for compensation information and details, since pay can vary by position and employer.

  • Can I find remote or hybrid California jobs?question toggle

    Some listings may offer remote or hybrid work, while others require on-site work. The job posting provides the employer’s location and work arrangement requirements.

  • How can I improve my California job search?question toggle

    Narrow your search by role, location, industry, and work arrangement. Keep your resume and profile updated, and carefully compare each opportunity’s qualifications and compensation details.