Explore $100K+ Jobs in California

Discover professional opportunities across California with Ladders. From established business centers to growing regional economies, the state offers senior-level roles in technology, healthcare, finance, entertainment, manufacturing, and more. Browse vetted job listings with salaries of $100,000 or higher and find positions that align with your experience and career goals.

California industries and career opportunities

California’s diverse economy supports leadership and specialized roles at companies of all sizes. Depending on your background, you may find opportunities in software and technology, life sciences, healthcare, financial services, clean energy, media, aerospace, and professional services. Job availability and compensation vary by role, employer, and location.

Find jobs throughout the state

Explore openings in major employment centers such as Los Angeles, San Francisco, San Diego, San Jose, Sacramento, and surrounding communities. Listings may include on-site, hybrid, and remote arrangements; review each posting for its work location and requirements.

Search with Ladders

Use Ladders to focus your search on vetted professional jobs paying $100,000 or more. Review role responsibilities, qualifications, compensation details, and workplace expectations, then apply directly to opportunities that fit your goals. Keep your profile and resume current so employers can better understand your experience.

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1,000+

Jobs in California

Average Salary in USD

Average Salary: $142,597

Sort By: Relevance

$143K - $192K *

Champion the development of technology business operations strategies, integrating software capitalization and resource analytics to drive informed investment decisions and operational excellence acro...

Today

  •   8 - 10 years exp.  •   Media

$174K - $234K *

Shape the future of Hematology analytics by leading strategic insights and performance initiatives. Collaborate with cross-functional teams to enhance field execution and drive commercial success thro...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$133K - $173K *

Drive compliance excellence by managing global monitoring programs and investigations. Collaborate with stakeholders to enhance compliance infrastructure and ensure adherence to regulations, while lea...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$105K - $140K *

Lead the charge in monitoring clinical study sites, ensuring data integrity and patient safety while collaborating with diverse teams to enhance study delivery and compliance with regulatory standards...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$121K - $206K *

Lead the charge in architecting and delivering Microsoft Azure and 365 solutions for SMBs. Oversee cloud migrations, security implementations, and project management while fostering strong partner rel...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Business Services

$97K - $165K *

Shape the future of cloud solutions by leading technical relationships, validating AWS architectures, and driving presales strategies. Empower teams through mentorship while ensuring secure, scalable...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Business Services

$74K - $124K *

Elevate compensation strategies by transforming complex data into actionable insights. Collaborate with stakeholders to manage compensation programs, analyze trends, and recommend solutions that ensur...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$485K *

Transform franchise growth in the Extended Stay sector by leading strategic initiatives, managing a team of Regional Vice Presidents, and building key relationships to enhance development opportunitie...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Hospitality & Recreation

$162K - $207K *

Lead the charge in implementing and optimizing SAP Vistex solutions, translating business strategies into technical architecture while managing cross-functional teams and project deliverables for enha...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$161K - $222K *

Drive operational excellence by leading a team focused on Lean transformation, continuous improvement, and productivity enhancement across manufacturing operations, partnering with cross-functional te...

Today

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$129K - $185K *

Unlock potential by leading the Customer Identity & Access Management function, overseeing CIAM platform operations, and driving identity strategy across global digital ecosystems while collaborating...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$136K - $231K *

Advance your career by developing innovative calibration solutions for semiconductor inspection systems. Leverage machine learning and advanced modeling to enhance accuracy, reduce time, and optimize...

Today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$106K - $181K *

Champion innovation by leading technical sourcing strategies for next-gen technologies. Collaborate across teams to ensure seamless execution and drive supplier partnerships that enhance product deliv...

Today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$138K - $235K *

Lead the charge in developing global product marketing strategies that drive business growth, enhance product positioning, and optimize market performance while collaborating across teams to deliver i...

Today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$120K - $135K *

Drive the evolution of our email marketing platform by owning architecture, integrations, and roadmap. Collaborate with cross-functional teams to enhance capabilities, ensuring effective audience targ...

Today

  •   5 - 7 years exp.  •   Legal & Accounting

$120K - $135K *

Champion the evolution of our email marketing platform, driving technical architecture, integrations, and campaign execution. Collaborate cross-functionally to enhance capabilities and ensure alignmen...

Today

  •   5 - 7 years exp.  •   Legal & Accounting

$120K - $135K *

Oversee the architecture and roadmap of an email marketing platform, ensuring effective campaign delivery and audience targeting. Collaborate with cross-functional teams to enhance platform capabiliti...

Today

  •   5 - 7 years exp.  •   Legal & Accounting

$120K - $135K *

Transform the future of email marketing by owning the architecture and roadmap of our email platform, ensuring effective audience targeting and seamless integrations while collaborating across teams t...

Today

  •   5 - 7 years exp.  •   Legal & Accounting

$120K - $180K *

Shape your career by developing strategic sales plans, conducting impactful presentations, and building strong relationships to achieve sales goals in the pharmaceutical sector while adhering to ethic...

RemoteRemote

Today

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$100K - $162K *

Unlock potential by developing effective strategies and relationships to drive sales growth in the territory, ensuring compliance with regulations and high levels of customer engagement through effect...

RemoteRemote

Reposted today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$72K - $108K *

Engage with targeted customers to drive sales growth through strategic planning, effective presentations, and relationship building while adhering to ethical practices and achieving quarterly goals in...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$72K - $108K *

Join a team that's dedicated to driving sales success through strategic planning and relationship building. You'll engage with customers, achieve sales goals, and enhance product awareness while foste...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Shape the future of hedge fund accounting by leading a dynamic team, enhancing client relationships, and driving operational excellence in a fast-paced environment. Your expertise will foster growth a...

Today

  •   Less than 5 years exp.  •   Enterprise Technology

$100K - $120K *

Lead a dynamic team in hedge fund accounting, enhancing client service and operational excellence while mentoring professionals in a fast-paced environment. Drive impactful results through collaborati...

Today

  •   Less than 5 years exp.  •   Enterprise Technology

$104K - $145K *

Elevate product development by defining, designing, and prototyping features for a merchant portal, leveraging AI tools and user feedback to enhance payment processing solutions rapidly and effectivel...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in California?question toggle

    California listings may include senior and specialized roles in technology, healthcare, finance, life sciences, entertainment, clean energy, manufacturing, and other fields. Available positions depend on current employer needs.

  • Where in California can I search for jobs?question toggle

    You can explore opportunities across the state, including major employment hubs such as Los Angeles, San Francisco, San Diego, San Jose, and Sacramento. Check each posting for its specific location and work arrangement.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for compensation information and details, since pay can vary by position and employer.

  • Can I find remote or hybrid California jobs?question toggle

    Some listings may offer remote or hybrid work, while others require on-site work. The job posting provides the employer’s location and work arrangement requirements.

  • How can I improve my California job search?question toggle

    Narrow your search by role, location, industry, and work arrangement. Keep your resume and profile updated, and carefully compare each opportunity’s qualifications and compensation details.