Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
Associate Creative Director, Copy
$150K - $170K *
Innovate creative strategies by leading diverse teams to deliver impactful communication projects, ensuring design and copy harmonize with strategic insights across various media channels...
1 week ago
Enterprise Account Director, New Business (API/CPaaS)
$120K - $157K *
Shape the future of enterprise sales by driving innovative strategies, fostering relationships, and generating revenue through a proactive approach in a dynamic, remote environment focused on large mu...
2 weeks ago
Account Executive, Life Sciences & Medtech
$147K - $220K *
Champion transformative health solutions by managing key client relationships, driving sales, and collaborating across teams to enhance Verily's impact in Life Sciences. Leverage expertise to unlock n...
2 weeks ago
Senior Enterprise Account Executive - West
$229K - $314K *
Drive success at large enterprise accounts, fostering relationships and ensuring robust account management. Collaborate across teams to elevate visibility and adoption, while navigating consultative s...
Reposted 3 weeks ago
Enterprise Account Executive, Corporate
$105K - $140K *
Lead the charge in driving new business for Fortune 1000 companies, utilizing your proven sales expertise. You'll own an extensive territory, managing the full sales lifecycle and collaborating closel...
Reposted 1 week ago
Associate Creative Director, Copy
$135K - $155K *
Elevate your career by leading creative copy initiatives that shape impactful healthcare messaging. Collaborate with cross-functional teams to deliver compelling content that resonates with diverse au...
1 week ago
$125K - $150K *
Accelerate growth by leveraging your extensive network to drive new business opportunities. Own the sales cycle from prospecting to closing, while shaping strategies that influence company success and...
1 week ago
$100K - $115K *
Take ownership of strategic account management to drive growth and enhance educational outcomes. Collaborate with key stakeholders, leverage data insights, and implement targeted strategies to maximiz...
3 days ago
Group Director, Client Media Solutions
$175K - $200K *
Lead the charge in developing integrated media strategies and client partnerships across pharmaceutical and life sciences accounts, driving business growth and ensuring exceptional delivery and client...
6 days ago
$145K - $175K *
Unlock potential by serving as a strategic advisor to enterprise clients, guiding them through complex stakeholder environments with predictive intelligence and data-driven insights to drive impactful...
1 week ago
Account Executive Director, Federal
$150K - $180K *
Drive growth by spearheading sales in the Federal sector, building relationships and managing pipelines to achieve new business revenue through strategic engagements with large Federal Agencies...
4 weeks ago
Strategic Account Manager - Southeast
$125K - $150K *
Drive strategic growth as you build relationships with C-level executives, lead complex sales cycles, and exceed quotas in selling enterprise-level SaaS solutions to $20bn+ clients while managing a de...
Reposted 3 weeks ago
Enterprise Account Executive - Business Services
$109K - $144K *
Drive success by managing strategic enterprise accounts in the Professional & Business Services sector. Leverage your expertise to enhance client relationships and optimize service delivery through a...
3 weeks ago
Director, Distribution Strategy
$172K - $203K *
Empower the distribution strategy by designing and managing rate content across channels, ensuring accurate delivery and partner trust. Collaborate with cross-functional teams to build scalable progra...
5 days ago
Senior Account Manager (Creator Marketing)
$85K - $115K *
Transform client relationships by leading innovative campaigns and strategies. Drive account growth and satisfaction while navigating the fast-paced creator landscape. Collaborate with teams to delive...
3 weeks ago
$85K - $105K *
Champion exceptional client relationships by delivering innovative solutions, managing campaigns, and driving strategic marketing goals to enhance performance and satisfaction for high-value clients i...
6 days ago
$165K - $180K *
Transform your career by driving new customer acquisition in healthcare. Leverage your expertise to build C-suite relationships and lead complex sales processes, contributing to the growth of a dynami...
1 week ago
$110K - $130K *
Champion strategic growth by managing key accounts, fostering relationships, and driving sales initiatives. Collaborate with leadership to meet customer needs and exceed performance objectives while r...
Reposted 1 week ago
$80K - $120K *
Grow your career with a dynamic sales role, driving supply chain transparency for leading brands. Own the full sales cycle, engage senior stakeholders, and develop solutions that enhance customer valu...
4 days ago
Client Director- US West (Professional Services Sales)
$132K - $199K *
Champion client success by driving Professional Services sales and revenue generation. Collaborate across North America to enhance client relationships and maximize value through effective solution im...
1 week ago
$145K - $150K *
Join a team that's redefining pay equity solutions. Drive sales cycles, engage with enterprise clients, and leverage innovative tech to ensure fair compensation practices. Collaborate with diverse sta...
1 week ago
$80K - $90K *
Drive growth by managing the complete sales cycle, from inbound leads to finalizing contracts. Collaborate across teams to ensure smooth customer transitions while exceeding sales targets with effecti...
3 weeks ago
$160K - $200K *
Unlock potential by leading strategic sales initiatives that drive growth and forge strong relationships with key retail and eCommerce clients in a fast-paced environment requiring frequent travel. In...
Reposted 3 days ago
$150K - $220K *
Unlock your potential by managing the full sales cycle, from prospecting to closing, while fostering lasting client relationships and exceeding sales goals in a fast-paced environment...
Reposted 1 week ago
Associate Director, Paid Social
$90K - $115K *
Lead strategic paid social initiatives, driving campaign excellence and team development across healthcare accounts. Collaborate with cross-functional teams to innovate and optimize performance, ensur...
Reposted 1 week ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.