Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
$77K - $104K *
Engage with customers to build a vibrant community and advocacy program. Drive strategy, foster relationships, and enhance customer experiences through data-driven insights and collaboration across te...
4 days ago
$228K - $285K *
Join us to build internal actuarial capabilities, measuring and pricing economic value across programs. Collaborate with Finance, Clinical, and Commercial teams to develop robust ROI models and perfor...
3 days ago
Program Manager - United Concordia Dental
$94K - $151K *
Shape the future of enterprise strategy by leading a diverse portfolio of programs and initiatives. Collaborate with cross-functional teams to drive measurable business value and ensure alignment with...
1 week ago
$120K - $150K *
Drive the marketing strategy and execution from the ground up. Collaborate with cross-functional teams to build scalable demand-generation programs to boost qualified pipeline and revenue for innovati...
Reposted 3 weeks ago
Multi-disciplinary Project Manager
$85K - $130K *
Grow and lead complex multidisciplinary projects from initiation to completion. Collaborate with diverse teams and clients to deliver high-quality results while managing budgets, schedules, and relati...
3 weeks ago
Senior Manager, Obesity Coverage and Value Strategy
$144K - $195K *
Oversee value-driven strategies for obesity coverage, enhancing payer access through robust communication and market analysis, while leading cross-functional partnerships and research to optimize cove...
3 weeks ago
Global Key Account Manager (USA) MedTech Solutions
$130K - $176K *
Lead the charge in driving strategic growth and retention for global key accounts. Collaborate across functions to enhance customer relationships and execute multi-year account strategies that align w...
5 days ago
Product Manager - Clinical Member Data
$86K - $138K *
Lead the charge in defining product vision and strategy, aligning stakeholders, and overseeing execution. Collaborate across teams to prioritize clinical data assets, ensuring maximum business value a...
1 week ago
$80K - $95K *
Drive the strategic direction of the Admissions Office, overseeing recruitment, enrollment, and outreach initiatives. Lead a team to achieve performance goals while fostering community relationships a...
4 days ago
Director Global Category Management - Mechanical
$180K - $225K *
Tackle the procurement lifecycle for mission-critical cooling equipment in data centers. Lead strategic initiatives, supplier performance, and operational excellence, while managing risks and driving...
Reposted 2 weeks ago
Senior Product Manager, Sales, Marketing & Business Solutions
$140K - $175K *
Join a dynamic team to drive the strategy and roadmap for Sales and Marketing platforms, focusing on Salesforce and marketing automation. Collaborate with stakeholders to prioritize initiatives and de...
1 week ago
$59K - $108K *
Drive successful live events and brand activations by supporting planning, execution, and post-event analysis. Collaborate with cross-functional teams to ensure seamless operations and maintain projec...
5 days ago
$110K - $130K *
Join a team that's dedicated to transforming complex business needs into scalable system solutions. Lead the analysis, documentation, and implementation of technical specifications while ensuring alig...
2 weeks ago
$69K - $107K *
Champion client success by leveraging technical expertise to enhance platform value, optimize workflows, and drive measurable outcomes. Collaborate with cross-functional teams to deliver innovative so...
3 weeks ago
VP OmniAnalyst Product Manager
$150K - $180K *
Transform enterprise data into valuable insights while leading AI-powered product strategies. Drive cross-functional collaboration to deliver secure, innovative, and measurable data capabilities that...
Reposted 3 weeks ago
$125K - $187K *
Analyze and negotiate complex contracts in healthcare, leveraging data-driven insights to enhance outcomes and drive strategic initiatives. Collaborate with stakeholders to optimize processes and fost...
4 weeks ago
$110K - $130K *
Join a dynamic team to evaluate strategic investments and growth opportunities in healthcare. Leverage market insights and financial modeling to shape multi-year business strategies, collaborating acr...
3 weeks ago
$160K - $200K *
Champion the development of policy strategies that guide product decisions, ensuring compliance and safety while navigating complex regulatory landscapes. Collaborate with cross-functional teams to tr...
2 weeks ago
National Sales Training Manager
$125K - $143K *
Drive the development and execution of tailored training programs, ensuring effective skill enhancement for sales representatives. Collaborate with cross-functional teams to align training strategies...
6 days ago
Vice President Enterprise Sales - Texas
$205K - $380K *
Accelerate progress at enterprise sales by driving strategic growth initiatives, building relationships with healthcare leaders, and leading complex sales pursuits to enhance market presence and custo...
3 weeks ago
Senior Technical Consultant - Data & Analytics
$160K - $200K *
Lead the charge in designing and implementing scalable data solutions, orchestrating pipelines, and supporting advanced analytics in cloud environments. Collaborate with teams to deliver robust data a...
2 weeks ago
Director, Global Commercial Planning and Forecasting
$160K - $190K *
Elevate your career by leading global commercial planning and forecasting efforts. Drive strategic decision-making, optimize supply allocation, and enhance business development through robust analytic...
5 days ago
Director, Strategic PartnershipsStrategic Partnerships & Business Development
$125K - $150K *
Join a team that's driving strategic partnerships in Retail and Hospitality. Manage relationships with technology providers, identify growth opportunities, and develop compelling business cases to enh...
1 week ago
Senior Financial Analyst, Cost Accounting
$58K - $125K *
Accelerate progress at the intersection of finance and strategy, driving cost accounting excellence and profitability analysis. Collaborate with cross-functional teams to enhance financial reporting a...
3 weeks ago
Strategic Account Manager - East Coast
$110K - $130K *
Join a team that's focused on driving growth in Healthcare and Financial Services. Leverage your enterprise sales expertise to build relationships, develop new business, and deliver impactful technolo...
2 days ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.