Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
$150K - $180K *
Transform enterprise relationships by driving strategic sales and fostering long-term partnerships in a dynamic AI infrastructure environment, engaging with C-level executives and guiding them through...
Reposted 3 weeks ago
$229K - $458K *
Champion strategic growth initiatives in advanced manufacturing, driving business development and forging key partnerships. Collaborate with cross-functional teams to enhance service offerings and mee...
5 days ago
AVP, Senior Product Manager - Agentic Workflows
$120K - $145K *
Explore innovative AI workflow solutions aimed at enhancing business processes. Collaborate with various teams to identify challenges, prototype solutions, and guide projects from conception to produc...
Reposted 1 week ago
Implementation Project Manager
$90K - $110K *
Champion client success by leading complex implementations, managing risks, and ensuring operational readiness. Collaborate with executive stakeholders to deliver projects on time while maintaining hi...
Reposted 3 days ago
High Velocity Account Executive - NAM
$80K - $100K *
Join us to drive rapid sales cycles and new customer acquisition in a dynamic, metrics-driven environment. You'll manage a robust pipeline, engage key stakeholders, and leverage digital tools to achie...
6 days ago
$110K - $125K *
Elevate your career by driving strategic sales initiatives in a dynamic environment. Leverage your expertise to build relationships, influence decision-makers, and expand market presence while managin...
1 week ago
Director of Business Development
$150K - $175K *
Grow your career with a leadership role in federal business development, driving strategy and execution for health programs. Lead capture management, build relationships, and mentor staff while contri...
2 days ago
Solution Architect & Pre-Sales, NetSuite
$120K - $160K *
Join a dynamic team to lead large-scale NetSuite projects, enhancing client experiences through strategic project management and collaboration. Utilize your expertise in pre-sales and implementation t...
Reposted 3 weeks ago
Strategic Account Executive, AMER
$125K - $150K *
Drive growth by hunting new logos and managing full-cycle enterprise deals across a 50-60-account territory. Collaborate with cross-functional teams to shape strategies and turn wins into repeatable m...
2 weeks ago
Associate Director, Compliance
$110K - $130K *
Drive the enhancement of Compliance Monitoring and Testing programs, ensuring regulatory alignment and effective risk management. Collaborate with stakeholders to improve operational efficiency and su...
5 days ago
$82K - $111K *
Serve as the primary client liaison, driving satisfaction and retention while fostering partnerships and implementing effective client strategies for healthcare products. Collaborate cross-functionall...
3 weeks ago
Director, Marketing Operations
$150K - $180K *
Lead the charge in optimizing marketing operations to drive developer adoption, pipeline growth, and revenue. Oversee systems, processes, and insights while collaborating with cross-functional teams t...
1 week ago
$199K - $370K *
Lead a dynamic team of Sales Specialists to drive growth and revenue in the Risk sector. Collaborate with leadership to enhance customer engagement, implement strategic solutions, and achieve sales ta...
3 weeks ago
$90K - $110K *
Grow your career with a dynamic team driving revenue through strategic business development in diverse markets. Build relationships, lead pursuits, and analyze trends to secure projects that shape com...
2 weeks ago
Senior Director, Service Manager
$163K - $261K *
Shape the future of electrification services by leading operations across the West U.S. region, driving performance excellence, and managing nationwide digital automation initiatives while advancing r...
Reposted 1 week ago
Senior Director, Data Architecture
$150K - $180K *
Champion enterprise data architecture by establishing standards and a unified data catalog. Collaborate across teams to define metrics and ensure data governance, driving alignment and clarity in a ha...
1 week ago
Director Manager CRM Klaviyo Email Marketing Lifecycle Loyalty
$140K - $170K *
Champion the future of customer engagement by leading lifecycle marketing strategies. Drive retention and loyalty through data-driven personalization across multiple channels, maximizing customer life...
1 week ago
Executive Director, Statistical Programming
$298K - $340K *
Join a dynamic team to lead strategic statistical programming initiatives, ensuring top-quality deliverables and compliance across diverse clinical trials. Collaborate with cross-functional partners t...
Reposted 3 weeks ago
Founding Senior Account Executive
$110K - $130K *
Drive Beam's growth by securing partnerships and expanding market presence. Lead the sales cycle for Beam Notes, engaging key sectors and refining strategies to enhance product-market fit in the US. Y...
Yesterday
$140K - $175K *
Join a team that's redefining partner management by owning high-value relationships, driving growth through strategic planning, and collaborating across departments to enhance customer outcomes and re...
1 week ago
Sales Director- Regional Enterprise Expansion
$124K - $165K *
Drive revenue growth as a key leader guiding a dynamic sales team focused on optimizing customer relationships and expanding market reach through strategic cross-selling initiatives and innovative sal...
Reposted yesterday
Director of Insurance Plan Management
$120K - $150K *
Transform the landscape of dental negotiations by leading strategic partnerships with payers, optimizing contracts, and driving revenue growth through data-driven insights and collaborative execution...
1 week ago
Principal Sales Infrastructure Analyst, Analytics Engineering
$156K - $204K *
Drive data alignment and enhance business processes by designing robust data pipelines and infrastructure. Collaborate with cross-functional teams to ensure data quality and accessibility, enabling ef...
2 weeks ago
$100K - $122K *
Unlock potential by leading a dynamic accounting team, managing full-cycle accounting processes, ensuring compliance, and driving process improvements in a fast-paced environment. Collaborate with fin...
3 weeks ago
Enterprise Core Account Executive - Public Sector
$222K - $278K *
Develop executive-level relationships and drive revenue growth in strategic accounts by managing the entire sales process. Champion our cultural principles while thriving in a dynamic, fast-paced envi...
Reposted 3 weeks ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.