Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
Senior Commercial Finance Analyst - Americas
$95K - $115K *
Drive financial excellence in Global Travel Retail by partnering with commercial teams to optimize pricing, investments, and performance analysis, ensuring sustainable growth and profitability across...
4 days ago
$115K - $160K *
Join a dynamic team as you manage accounts, drive sales of SAP services, and cultivate customer relationships. Leverage your expertise to develop strategic plans, generate demand, and lead cross-funct...
1 week ago
$100K - $120K *
Reimagine business development by driving a dynamic sales pipeline across defense, renewable, and oil & gas sectors. Build lasting client relationships while identifying new market opportunities to ac...
1 month ago
Senior Manager, Revenue Operations
$156K - $195K *
Own the end-to-end B2B2C enrollment funnel by transforming data into actionable insights, optimizing processes, and leading cross-functional collaboration to enhance growth and ensure successful membe...
Reposted 3 weeks ago
$115K - $160K *
Transform customer relationships by leading strategic SAP solutions sales, driving growth, and managing complex accounts. Collaborate with cross-functional teams to deliver tailored services and ensur...
1 week ago
$115K - $140K *
Help us drive success by coordinating bid opportunities across defense and commercial sectors. You'll manage the entire proposal process, ensuring compliance and collaboration among cross-functional t...
Yesterday
$150K *
Transform US commercial operations, leading growth through innovative revenue strategies, while enhancing patient experience and building high-performing teams across regional and clinical leadership...
1 month ago
Project Manager, Business Improvement
$100K - $120K *
Empower your career by driving impactful business improvement initiatives. Collaborate with cross-functional teams to manage projects, analyze data, and enhance operational efficiency in a dynamic env...
1 week ago
$242K - $282K *
Lead the oversight of contractual matters across departments, serving as a trusted advisor to internal stakeholders from pre-clinical to commercial readiness. This role emphasizes collaboration and ex...
Reposted 3 weeks ago
Account Executive (San Antonio, TX)
$85K - $100K *
Join a team that's dedicated to building strong client relationships through face-to-face sales. Leverage your expertise in outside sales to drive growth and maximize your earning potential in a dynam...
1 week ago
Experiential Creative Director - Exhibit Activations - Remote
$110K - $130K *
Champion immersive experiences by leading creative teams to craft compelling narratives in healthcare and aerospace exhibitions, ensuring impactful audience engagement and innovative design solutions...
5 days ago
$144K - $230K *
Champion business growth by developing and closing new opportunities in the broker-dealer segment, while managing strategic accounts and building executive relationships to drive value through innovat...
Reposted 4 weeks ago
$80K - $95K *
Join a team that's dedicated to optimizing privacy management processes and compliance technology. This role supports platform administration, user engagement, and operational improvements, ensuring e...
1 week ago
$110K *
Elevate channel strategy and partner relationships to drive revenue growth, enhance market positioning, and ensure effective collaboration across teams, while managing negotiations and performance met...
3 weeks ago
Regional Sales Director, Enterprise - Southeast
$148K - $248K *
Shape the future of software sales by leading a dynamic team in the Southeastern US. Drive revenue growth, enhance customer relationships, and foster a high-performing culture while leveraging GitLab...
1 week ago
Enterprise Account Executive - Financial Services, New York/Northeast
$98K - $187K *
Lead the charge in transforming financial services by driving enterprise sales of a cutting-edge SaaS platform. Collaborate with top-tier clients to enhance customer experiences and achieve strategic...
2 weeks ago
$175K - $225K *
Contribute to the growth of our retail segment by leading human capital strategies that optimize talent acquisition, performance management, and organizational design in alignment with business object...
Reposted 2 weeks ago
Regional Manager, Channel Central
$150K - $180K *
Transform the Central Region's channel strategy by leading a high-performing team, driving revenue growth, and fostering strategic partnerships. Collaborate with executives to align goals and maximize...
1 week ago
Key Account Manager - Casino Gaming
$100K - $125K *
Grow key accounts in the Casino Gaming sector by driving business expansion, identifying opportunities, and delivering tailored computing solutions. Engage with C-level executives to enhance partnersh...
1 week ago
Associate Director- Model Audit, Model Build and Transactions Advisory
$120K - $145K *
Drive excellence by leading model audits and mentoring a dynamic team. Collaborate on complex financial models, ensuring accuracy and strategic growth, while enhancing methodologies to deliver top-not...
Reposted yesterday
Project Manager - Power Solutions
$165K - $185K *
Grow your career with us by leading complex electrical power solutions projects. Collaborate with diverse teams to deliver innovative solutions for mission-critical facilities, ensuring projects meet...
2 weeks ago
Senior Media Planner (Integrated)
$75K - $90K *
Elevate your career as you drive powerful media strategies, collaborating with teams and clients to optimize performance across various channels, leveraging insights for impactful digital campaigns in...
Reposted 3 days ago
Manager of Account Management, Large Group Segment - Cigna Global Health Benefits (GHB) - Remote
$110K - $130K *
Develop strategic leadership for a team managing complex client portfolios, driving retention, growth, and client experience objectives while fostering strong relationships with stakeholders and ensur...
2 days ago
$80K - $95K *
Drive financial accuracy and compliance as a Senior Accountant. Lead month-end close, maintain internal controls, and support auditors while refining processes. Ideal for proactive self-starters seeki...
Reposted 3 weeks ago
Supervisor, Media Strategy & Client Partnerships
$102K - $122K *
Champion client partnerships by driving strategic media campaigns and fostering relationships. Leverage your expertise in DTC paid media to enhance client success and team collaboration, ensuring impa...
1 week ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.