Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
Senior Director, Contact Center
$150K - $180K *
Lead the future of patient experience by driving strategic initiatives and operational excellence in a high-volume healthcare contact center. Collaborate with cross-functional teams to enhance service...
1 week ago
$120K - $150K *
Join our team to lead innovative process improvement initiatives that enhance operational efficiency and deliver measurable results. Drive cross-functional collaboration and cultivate a culture of con...
Reposted 3 weeks ago
Senior Financial Analyst (Product & Delivery)
$100K - $120K *
Drive financial excellence by integrating and analyzing revenue and expense forecasts, ensuring alignment across functions. Collaborate with FP&A teams to deliver actionable insights and support strat...
2 weeks ago
$125K - $150K *
Join a team that's redefining enterprise sales by engaging C-suite stakeholders in Tier 1 banks and credit unions. Drive complex sales cycles, build strategic relationships, and deliver tailored solut...
3 days ago
Enterprise Account Executive - Warehouse Robotics (North America)
$150K *
Champion new business across North America by selling autonomous mobile robots. Own the sales process, develop complex relationships, and structure high-value agreements, while driving innovative stra...
4 weeks ago
Director of Retirement Sales Activation
$130K - $140K *
Drive efficiency and scalability in onboarding processes, enhancing customer experience through innovative strategies and data-driven leadership. Lead a high-performing team to optimize resources and...
2 weeks ago
$200K *
Lead the charge in building and scaling AI Data Operations, transforming emerging opportunities into commercially viable solutions. Drive strategy, partnerships, and operational excellence to support...
2 weeks ago
Director, Strategic Partnerships
$168K - $285K *
Drive strategic partnerships by shaping and executing initiatives that align with AI and business priorities. Collaborate across teams to develop relationships and deliver measurable outcomes that enh...
Reposted 3 weeks ago
Business Development Manager - EU
$109K - $186K *
Champion business growth across European defense markets by developing strategies, engaging stakeholders, and managing sales cycles. Build long-term relationships to position solutions as the preferre...
2 weeks ago
$109K - $164K *
Drive advanced digital forensics and incident response initiatives while mentoring a skilled engineering team. Leverage deep technical knowledge to enhance operational capabilities and ensure exceptio...
Reposted 1 week ago
Account Executive - Healthcare (Northeast)
$125K - $150K *
Champion growth by building strategic relationships and driving sales in the Healthcare sector. Leverage AI solutions to enhance customer engagement and achieve revenue targets while collaborating wit...
1 week ago
Director - AI Digital Product Management - Commercial Value & Access
$199K - $269K *
Grow your career with a leadership role in AI Digital Product Management, driving strategy and innovation across a portfolio of AI products. Collaborate with cross-functional teams to deliver scalable...
2 weeks ago
Strategic Account Executive - West
$105K - $110K *
Drive success by leading complex sales strategies for education solutions, fostering relationships with senior leaders, and shaping long-term partnerships that enhance operational efficiency and commu...
1 week ago
$71K - $119K *
Partner with us to lead client relationships, ensuring satisfaction and operational excellence. Manage onboarding, project delivery, and service performance while collaborating across teams to drive s...
1 week ago
Business Development Executive
$100K - $120K *
Drive new logo acquisition and revenue growth by managing the full sales cycle for assigned prospects, leveraging industry expertise and consultative selling to deliver tailored solutions and achieve...
3 weeks ago
Director of Business Operations
$125K - $150K *
Transform business operations by leading systems and technology initiatives that enhance efficiency, drive AI enablement, and streamline processes across the organization, ensuring a robust foundation...
1 week ago
Client Growth & Success Principal Manager- Enterprise Accounts
$150K - $175K *
Shape the future of client partnerships by driving strategic growth and success for large enterprise organizations. Collaborate with cross-functional teams to deliver exceptional value and measurable...
1 week ago
Director of Strategic Accounts, Central U.S.
$135K - $160K *
The Director of Strategic Accounts is responsible for developing and closing business with Motive's largest prospects, primarily targeting Fortune 500 companies. This role involves building relationsh...
Reposted 1 week ago
$160K - $192K *
Drive commercial performance by engaging healthcare providers and executing territory plans. Collaborate with cross-functional teams to support product launches and ensure patient access to innovative...
2 weeks ago
$80K - $90K *
Lead the charge in managing comprehensive accounting functions for self-insurance groups, ensuring accurate financial reporting, compliance with regulations, and effective budget management while coll...
1 week ago
$120K - $145K *
Join a dynamic finance team as you oversee financial reporting, manage reconciliations, and enhance accounting processes. Your expertise will ensure compliance with GAAP while supporting audits and op...
Reposted today
Director, Client Coding Integration
$120K - $145K *
Execute accurate coding practices to ensure compliance and optimal reimbursement in a dynamic healthcare environment. Collaborate with clinical teams to maintain integrity and efficiency in revenue cy...
Reposted 6 days ago
Commercial & Industrial Account Manager
$80K - $95K *
Join a team that's focused on driving growth and customer satisfaction in the commercial and industrial sector. Leverage your sales expertise to manage accounts, resolve customer issues, and identify...
2 days ago
Contracts & Pricing Strategy, Associate Director
$151K - $204K *
Join a team that drives pricing and contracting strategies to enhance market access for innovative treatments, collaborating across functions to optimize value and implement effective launch plans whi...
3 weeks ago
Strategic Account Executive, Growth | Bay Area | Remote |
$320K - $340K *
Join a dynamic team to drive growth by nurturing and expanding existing accounts. Leverage your strategic sales expertise to cultivate strong customer relationships and achieve ambitious sales goals i...
Reposted 3 weeks ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.