Explore $100K+ Jobs in South Dakota

Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.

South Dakota career opportunities

South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.

Where to find jobs

Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.

Find the right role on Ladders

Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.

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1,000+

Account Director Jobs in South Dakota

Sort By: Relevance

$73K - $130K *

Deliver accurate financial reporting and account management by executing journal entries, reconciliations, and month-end close activities while collaborating with a dynamic accounting team to ensure c...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Transportation

$148K - $248K *

Drive growth by leading a field-based sales team focused on federal agencies. You'll strategize, coach, and negotiate to enhance adoption of our DevSecOps platform, ensuring alignment with agency need...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Inspire and elevate design excellence as you lead a talented team, setting and maintaining visual standards, driving innovative campaigns, and partnering cross-functionally to advance Dandy's brand an...

United StatesRemote

Reposted 4 days ago

  •   8 - 10 years exp.  •   Healthcare

$327K - $408K *

Lead the charge in shaping long-term marketing strategies and partnerships, overseeing a dynamic team to drive growth and enhance market positioning through innovative co-marketing initiatives and cro...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Finance & Insurance

$84K - $100K *

Transform premium accounting operations by leading teams, ensuring compliance, and driving process improvements through analytics and AI tools. Collaborate cross-functionally to enhance service levels...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$142K - $197K *

Drive strategic improvements and operational efficiency in Partnerships by establishing frameworks, integrating AI solutions, and optimizing team performance, all while collaborating with cross-functi...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$105K - $169K *

Manage strategic partnerships with ACE and EJD to drive sales growth. Collaborate with merchandising and logistics teams to implement promotional programs and enhance market share across all brands wi...

RemoteRemote

4 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$222K - $278K *

Lead strategic customer engagements to transform enterprise operations, streamline workflows, and generate insights. You'll drive high-value sales, navigate complex negotiations, and cultivate lasting...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$40K - $200K *

Join a dynamic team to drive business growth through consultative sales, building lasting client relationships, and delivering innovative payment solutions. This role offers uncapped earnings and oppo...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$115K - $120K *

Lead the charge in driving operational excellence and strategic enablement across global Inside Sales teams, enhancing commercial effectiveness and delivering exceptional client value through innovati...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Champion the monthly close process, ensuring accuracy and scalability across multi-entity operations while driving continuous improvement and automation in accounting practices...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$222K - $278K *

Take ownership of enterprise-level sales, driving strategic relationships and complex negotiations to deliver impactful solutions for key customers. Engage with C-Level executives to transform operati...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$100K - $120K *

The Strategic Account Executive at Virtuous will leverage inbound and outbound sales techniques to sell complex cloud-based software solutions to large and medium-sized nonprofits. This role involves...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $95K *

Empower growth by developing strategic relationships with biotech and pharma clients. Drive market awareness and increase RFPs through collaboration with the business development team, leveraging your...

RemoteRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Champion client success by overseeing relationships, ensuring operational excellence, and mentoring teams to exceed expectations. Utilize analytics to drive performance and resolve issues, fostering c...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Join a team that's dedicated to enhancing client relationships and driving success. Oversee client performance, mentor staff, and ensure compliance while collaborating with various departments to deli...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$175K - $220K *

Shape the future of healthcare real estate by leading a dynamic transaction management team. Oversee negotiations, staff development, and strategic planning to drive client success and enhance operati...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$75K - $100K *

Tackle a diverse array of standard-complexity projects, driving efforts from planning through execution while ensuring timelines are met and communications are clear. Collaborate effectively with clie...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Media

$200K - $220K *

Lead strategic policy initiatives and public affairs to drive next-gen power infrastructure deployment with carbon capture. Engage stakeholders and influence regulatory frameworks to support sustainab...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Energy & Utilities

$125K - $150K *

Drive your career forward by leading client engagement and market development in Knowledge & Research Services. Build relationships, shape client needs, and oversee impactful programs while collaborat...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$195K - $230K *

Drive growth by leading go-to-market strategies for TMC partnerships, building and executing plans from the ground up. Collaborate cross-functionally to influence product development and represent the...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$130K - $195K *

Drive enterprise sales success by engaging CIOs and CTOs, leading complex sales cycles, and connecting technology solutions to business outcomes. Leverage your expertise in cloud architecture and AI t...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Consumer Technology

$100K - $125K *

Develop and execute strategies to enhance client engagement in the Military, Aerospace, and Government sectors, driving new business opportunities and managing key accounts to maximize value and foste...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$170K - $230K *

Accelerate growth by leading a high-performing sales team in the Professional Services & Consulting sector. Drive strategy, performance, and revenue while fostering a culture of collaboration and exce...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Consumer Technology

$162K - $243K *

Lead a dynamic team in managing complex clinical research trials, ensuring project execution aligns with strategic objectives. Drive process improvements and maintain client relationships while overse...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000-plus jobs are available in South Dakota?question toggle

    Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.

  • Which South Dakota cities have professional job opportunities?question toggle

    Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.

  • How can I find high-paying jobs in South Dakota?question toggle

    Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.

  • Do South Dakota jobs listed on Ladders all pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.