Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
$114K - $163K *
Empower beverage innovation by driving sales growth and strategic partnerships. Manage customer relationships, lead negotiations, and collaborate across teams to deliver tailored solutions in the alco...
1 week ago
Senior Manager, Transaction Advisory
$500K+*
Lead the execution of carbon transaction advisory across LAC countries, managing senior government relationships and developing commercialization strategies to support forest protection initiatives an...
Yesterday
Senior Manager, Business Systems
$110K - $130K *
Lead the enhancement of finance systems in a dynamic environment, focusing on optimizing NetSuite and integrating additional solutions. This role involves strategy, system configuration, and process i...
3 weeks ago
$110K - $130K *
Lead the charge in delivering exceptional service and support to customers, managing maintenance operations, and executing technical strategies while fostering talent development and ensuring high-qua...
6 days ago
$108K - $162K *
Join a team that's dedicated to enhancing biomedical service operations. Lead a skilled team of technicians, ensuring high-quality support and customer satisfaction across the Pacific Northwest while...
3 weeks ago
$123K - $158K *
Unlock your potential by driving enterprise sales growth across the Americas. Collaborate with cross-functional teams to manage the full sales cycle, from prospecting to closing, while building strong...
Yesterday
$97K - $118K *
Lead the charge in developing and executing strategic sales initiatives for large accounts, fostering key relationships to drive long-term revenue growth and market penetration while collaborating acr...
2 weeks ago
$176K - $293K *
Develop and implement strategic account plans to drive sales growth and build relationships with key decision-makers in healthcare. Collaborate with cross-functional teams to achieve business goals an...
2 weeks ago
Senior Account Manager | Retail
$94K - $151K *
Build strategic partnerships and drive growth for a portfolio of major retail accounts. Own the full account lifecycle, develop tailored solutions, and lead cross-functional teams to deliver exception...
1 week ago
$88K - $110K *
Unlock growth by owning the TPA/PEO sales strategy, managing complex accounts, and driving revenue across diverse deal sizes. Collaborate with cross-functional teams to deliver tailored solutions and...
2 weeks ago
$125K - $150K *
Elevate your career by leading conversion optimization strategies for DTC brands. Utilize data analytics and behavioral science to drive revenue through testing, insights, and AI-driven personalizatio...
3 weeks ago
Strategic Account Manager Sr Lead
$177K - $301K *
Develop and lead strategic client growth initiatives, fostering executive relationships and aligning teams to drive long-term value, retention, and measurable outcomes across a portfolio of enterprise...
1 week ago
Account Executive (Enterprise Legal Management)
$125K - $150K *
Drive enterprise sales growth by leading complex sales cycles in Fortune 500 legal departments. Close multi-million dollar deals while orchestrating solutions and services to replace fragmented legal...
4 weeks ago
Senior Account Executive, Business Outfitters
$100K - $120K *
Lead the charge in managing multi-million-dollar Key Accounts, driving revenue growth through strategic relationships and collaboration with internal teams. Own account strategies, exceed sales target...
3 weeks ago
$120K - $150K *
Transform your career by owning full-cycle sales for top-tier accounts. Drive pipeline growth, engage complex stakeholders, and close high-value deals while collaborating with a dedicated team in a dy...
Reposted 2 weeks ago
$100K - $120K *
Join a team that's driving sales success by navigating complex organizations, understanding customer objectives, and consistently achieving revenue targets through strategic execution and collaboratio...
1 month ago
$180K - $220K *
Empower growth in Generative AI by building relationships, driving revenue, and collaborating cross-functionally to deliver innovative solutions while achieving client satisfaction and sales targets i...
Reposted 2 weeks ago
$110K - $130K *
Drive growth by managing strategic enterprise accounts, cultivating relationships, and delivering tailored solutions that align with client objectives while exceeding sales targets and enhancing custo...
1 week ago
Business Development Director, OEM Partnerships
$135K - $160K *
Transform OEM partnerships by driving strategic growth and innovative solutions. Leverage market insights and relationship-building skills to negotiate impactful deals and collaborate with senior lead...
4 days ago
$115K - $130K *
Lead the Archibus platform for a major Life Sciences client, driving enhancements and integrations while ensuring data integrity and user satisfaction. Collaborate with cross-functional teams to optim...
Yesterday
$150K - $180K *
Shape the future of billing operations by leading a team to enhance accuracy, timeliness, and efficiency. Drive process improvements, manage complex accounts, and collaborate across functions to resol...
3 days ago
Director of Sales, Pacific Northwest - Remote (PST)
$200K - $300K *
Accelerate sales growth in the Pacific Northwest by leading a dynamic team in Washington, Oregon, and Idaho. Drive accountability, enhance pipeline management, and foster a high-performance culture th...
Reposted 3 days ago
$120K - $145K *
Help us shape the future of our brand by leading creative initiatives across campaigns, digital channels, and events. Collaborate with marketing teams to ensure a consistent visual identity and impact...
1 week ago
$126K - $198K *
Engage with us to lead a high-performing team managing enterprise deal operations, ensuring effective execution and strategic advisory support across complex transactions and product offerings for the...
3 weeks ago
Account Executive, SME & Growth (Pacific Time Zone)
$100K - $120K *
Drive the full sales cycle for fintech solutions, engaging SMEs across various sectors. Leverage your expertise to exceed revenue targets while ensuring exceptional customer onboarding and success in...
6 days ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.