Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
$150K - $170K *
Partner with us to drive growth and strengthen relationships with key strategic accounts. Leverage your expertise in enterprise sales to identify opportunities, ensure renewals, and deliver measurable...
2 weeks ago
Senior Account Executive - NY/NJ BFSI
$120K - $150K *
Lead strategic sales initiatives by uncovering new opportunities, managing relationships with C-level executives, and executing a comprehensive sales process to achieve quarterly and annual quotas in...
5 days ago
Managing Director - Digital Infrastructure, Investment Banking
$210K - $250K *
Lead growth initiatives in digital infrastructure investment banking, driving deal origination, client relationships, and team mentorship while ensuring exceptional service delivery and execution exce...
Reposted 3 weeks ago
Sr. Director, Google Practice Lead
$150K - $200K *
Shape the future of our Google ecosystem business by driving growth, developing high-performing teams, and ensuring exceptional client delivery. Balance strategic leadership with hands-on execution to...
Reposted 1 week ago
$90K - $100K *
Join a team that's dedicated to transforming healthcare through creativity and strategy. As an Account Supervisor, you'll lead client projects, foster relationships, and mentor junior staff, ensuring...
Reposted 1 week ago
Director/Senior Director Commercial Business Development
$175K - $210K *
Unlock potential by leading strategic business development initiatives that connect biopharmaceutical executives with tailored commercial solutions. Drive growth through relationship-building and inno...
3 days ago
Key Account Director, Mortgage
$125K - $150K *
Accelerate growth by driving strategic sales initiatives and expanding key accounts. Leverage your expertise in complex sales cycles to secure new business and enhance existing relationships within th...
2 weeks ago
$125K - $150K *
Drive integrated, compliant media strategies for pharmaceutical brands, leading channel planning, investment decisions, and client engagement to achieve impactful business outcomes throughout launch a...
Reposted 3 weeks ago
$80K - $95K *
Shape the future of client relationships in the metals industry by driving sales, managing key accounts, and ensuring customer satisfaction. Leverage market expertise to identify opportunities and fos...
2 days ago
Sr. Account Executive, Enterprise
$112K - $150K *
Unlock potential by driving enterprise sales to Fortune 500 clients, managing end-to-end sales cycles, and fostering strategic relationships with C-level executives to deliver impactful SaaS complianc...
4 days ago
EA-Account Executive, National Campaigns
$68K - $168K *
Transform political engagement by driving software sales within a designated U.S. territory. Build relationships with Democratic officials and campaign professionals while managing outreach and client...
2 days ago
Regional Client Director, West
$156K - $234K *
Transform strategic healthcare partnerships by leading complex account initiatives, driving growth, and enhancing customer engagement across diverse Integrated Delivery Networks and Group Purchasing O...
3 days ago
Strategic Business Development Executive
$150K - $180K *
Join a team that's driving innovation in legal technology by leveraging your extensive sales expertise to acquire new enterprise accounts and exceed revenue targets across the Americas, while collabor...
1 week ago
Account Executive - Compliance Sales
$88K - $150K *
Shape the future of cybersecurity by driving growth in strategic accounts. Leverage your expertise to build executive relationships, navigate complex sales cycles, and expand our compliance audit and...
1 week ago
$100K - $120K *
Unlock potential by leveraging your expertise in data analysis and psychometrics to drive innovative assessment solutions. Collaborate with a dynamic team to enhance educational outcomes through advan...
2 weeks ago
$250K - $315K *
Unlock potential by driving sales excellence and building client relationships. Be a proactive hunter and product expert in a fast-paced startup, ensuring customer satisfaction while shaping our innov...
Reposted 3 weeks ago
Senior Manager, Key Accounts (Providers)
$120K - $140K *
Empower provider accounts post-launch by driving growth through strategic engagement, tailored training, and effective collaboration with internal teams. Cultivate relationships across diverse healthc...
1 week ago
Director, Consultant Relations
$130K - $170K *
Partner with us to enhance consultant relationships in healthcare. Drive business growth by cultivating partnerships, optimizing engagement strategies, and aligning internal teams to effectively posit...
3 weeks ago
$100K - $120K *
Empower healthcare organizations by driving sales of innovative Nurse Call solutions. Own the full sales cycle, engage with senior leaders, and leverage your expertise to navigate complex deals in a d...
2 days ago
Associate Director, Regional Marketing (Midwest Region)
$120K - $145K *
Join a team that's driving regional marketing initiatives in hematology and oncology. Engage with key thought leaders, execute strategic plans, and leverage local opportunities to enhance brand presen...
2 weeks ago
$135K - $170K *
Optimize your sales career by managing the full sales cycle for a leading engineering software. Leverage your technical expertise to drive revenue growth and deliver impactful solutions to industrial...
1 week ago
Associate Director, Converged TV
$129K - $147K *
Champion innovative digital video strategies, focusing on CTV, while leading cross-functional teams to optimize campaign performance and drive growth in a dynamic advertising environment...
2 days ago
$100K - $150K *
Build strategic partnerships and drive revenue growth by managing high-potential accounts. Collaborate with internal teams to enhance partner engagement and achieve production targets while fostering...
3 weeks ago
Account Executive, Commercial West
$300K - $350K *
Lead the charge in driving enterprise revenue across the West territory, engaging with senior security leaders in regulated industries. Shape strategic sales initiatives and build lasting relationship...
Yesterday
$110K - $130K *
Transform your career by driving sales for innovative SaaS solutions in a dynamic environment. Leverage your expertise to engage Fortune 1000 clients, navigate complex sales cycles, and exceed revenue...
2 weeks ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.