Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From positions in Jackson and the Gulf Coast to opportunities in communities across the state, find roles that match your experience, skills, and career goals.

Professional Opportunities Across Mississippi

Mississippi employers hire experienced professionals across industries such as healthcare, finance, manufacturing, technology, energy, and business operations. Available roles and compensation vary by employer, location, and qualifications, so review each listing for details about responsibilities, salary, and requirements.

Search in Mississippi Cities and Regions

Find opportunities in major employment centers including Jackson, Gulfport, and Southaven, as well as other Mississippi communities. Use location and job-title filters to focus your search, and consider remote or hybrid listings when available.

Find a Role That Fits Your Career

Compare opportunities by seniority, specialty, and work arrangement. Keep your résumé current, highlight measurable results, and tailor your application to the qualifications in each listing. Ladders helps professionals explore vetted jobs with salaries of at least $100,000.

Start Your Mississippi Job Search

Browse Mississippi jobs on Ladders and take the next step toward a professional opportunity aligned with your expertise and compensation goals. Listings change frequently, so check back for new roles.

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$120K - $150K *

Drive customer satisfaction and sales in life sciences by leveraging your expertise to build relationships and execute strategic initiatives with key accounts in academia and industry...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Lead the charge in managing contracts for utility-scale solar and infrastructure projects. Collaborate with cross-functional teams to ensure compliance, streamline documentation, and support project c...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$123K - $135K *

Engage with existing customer accounts to drive renewal retention and expansion revenue. Collaborate with cross-functional teams to identify growth opportunities and ensure customer satisfaction while...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$160K - $200K *

Shape the future of our web strategy by leading a cross-functional team to optimize user experience, drive demand generation, and enhance web performance. Your expertise will transform our website int...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$100K - $130K *

Drive commercial activation and revenue growth for a multi-million-dollar portfolio, leveraging strategic insights and AI to enhance client engagement and decision-making. Lead cross-functional teams...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$165K - $200K *

Lead the charge in driving commercial activation and revenue growth for a multi-million-dollar portfolio, leveraging strategic insights and AI to enhance client engagement and deliver measurable resul...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$95K - $110K *

Shape innovative marketing strategies as a Senior Art Director, leading creative projects that align with client objectives. Collaborate with teams to deliver impactful visual content, driving busines...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $120K *

Engage in strategic pipeline development to drive revenue across LATAM and North America. Utilize consultative selling and AI tools to connect with technical decision-makers, ensuring high-quality out...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$120K - $150K *

Join a team that's shaping the future of consulting in P&C insurance. Lead client engagements, ensure quality standards, and foster long-term relationships while driving business growth and mentoring...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$125K - $150K *

Join us to drive full-cycle sales of an innovative AI platform, engaging top audit and advisory firms. Build relationships, implement strategies, and redefine industry standards while navigating compl...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$112K - $143K *

Drive new business growth and expand relationships in your territory. Collaborate with brokers, consultants, and partners to achieve revenue targets while maintaining a strong field presence and deliv...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$190K - $210K *

Unlock data-driven insights as a hybrid leader, balancing hands-on analytics with high-level client strategy. Drive impactful initiatives and foster cross-functional collaboration to deliver valuable...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Healthcare

$192K - $334K *

Tackle complex healthcare M&A engagements, leading due diligence efforts, and collaborating with clients and teams to drive value. Manage multiple projects while utilizing your expertise to influence...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Legal & Accounting

$157K - $256K *

Shape strategic pricing and channel strategies for innovative therapies, ensuring patient access and affordability. Lead cross-functional initiatives, optimize distribution models, and drive market in...

United StatesRemote

3 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$108K - $196K *

Shape the future of healthcare by managing client relationships and optimizing clinical programs. Collaborate with teams to drive client success and ensure alignment with company goals, leveraging dat...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Unlock your potential by driving sales growth in the Enterprise ERP market. Engage with diverse clients, manage sales cycles, and foster strategic partnerships to enhance our Digital Transformation pr...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$97K - $145K *

Join a team that's dedicated to ensuring accurate coding and compliance for clinical services, leveraging your expertise to enhance revenue cycle management and contribute to optimal healthcare outcom...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$180K - $215K *

Lead the charge in transforming supply chain technology strategies, driving innovation and operational excellence across S2P and O2C value streams. Collaborate with cross-functional teams to enhance d...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$160K - $190K *

Lead the charge in shaping user experiences by driving product design strategy, mentoring teams, and collaborating with cross-functional partners to tackle complex enterprise challenges and enhance de...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Transportation

$90K - $115K *

Join a dynamic team as a Senior Project Planner, driving financial health and vendor coordination across multiple brands while ensuring project success through strategic planning and effective communi...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$135K - $160K *

Lead data-driven strategies to enhance revenue growth across customer acquisition, retention, and expansion. Collaborate with cross-functional teams to establish integrated metrics and actionable insi...

RemoteRemote

Today

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$193K - $262K *

Champion the sales force's success by leading a dynamic team focused on optimizing field effectiveness and operational efficiency, driving excellence in performance and insights...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$148K - $234K *

Lead strategic data governance initiatives, ensuring high-quality, compliant data across domains. Collaborate with stakeholders to prioritize efforts, resolve issues, and drive alignment for impactful...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$128K - $170K *

Empower executive leadership with strategic financial insights to drive growth initiatives. Collaborate on M&A, pricing, and R&D investments while delivering actionable recommendations in a fast-paced...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$240K - $300K *

Empower strategic partnerships across the Eastern U.S. to drive revenue growth. Build and manage a partner-sourced pipeline, enhance customer engagement, and accelerate deal closures through collabora...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of jobs can I find in Mississippi on Ladders?question toggle

    You can explore professional opportunities across fields such as healthcare, finance, manufacturing, technology, energy, and business operations. Roles and availability vary over time.

  • Are Mississippi jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional jobs that pay $100,000 or more. Check each listing for compensation details, qualifications, and other job-specific information.

  • Where in Mississippi can I search for jobs?question toggle

    Search across the state, including employment centers such as Jackson, Gulfport, and Southaven. You can use location filters to narrow results.

  • How can I find remote or hybrid jobs based in Mississippi?question toggle

    Use available work-arrangement filters or review listing details to identify remote and hybrid opportunities. Availability depends on the employer and role.

  • How do I improve my chances of getting hired for a Mississippi job?question toggle

    Tailor your résumé to the role, emphasize relevant experience and measurable outcomes, and ensure you meet the listed qualifications before applying.