Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$180K - $195K *

Join a team that's revolutionizing cloud-based investment solutions. As an Associate Director, you'll lead operations, shape AI-driven practices, and innovate scalable architectures to enhance perform...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$100K - $110K *

Engage in impactful fundraising efforts to support educational leadership initiatives. Manage a diverse portfolio of donors, develop strategic engagement plans, and collaborate across teams to secure...

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$130K - $160K *

Drive program success by coordinating cross-functional teams, managing reporting, and optimizing engagement strategies for a global enterprise account, ensuring alignment with client goals and employe...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$185K - $215K *

Transform the future of market research in biotechnology by delivering crucial insights and competitive intelligence that drive strategy for investigational therapies. Collaborate cross-functionally a...

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Join a team that's dedicated to enhancing executive effectiveness through strategic support, project management, and seamless communication. This role is pivotal in ensuring priorities align and initi...

Wilmington, MARemote

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Join a dynamic team as a strategic partner to senior executives, optimizing schedules, managing projects, and enhancing communication. This role requires discretion and strong organizational skills to...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$175K - $237K *

Lead transformative initiatives by developing business cases and change strategies. Collaborate with senior leaders to drive alignment and manage complex change processes across multiple functions, en...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $120K *

Shape the future of sales by driving complex B2B SaaS solutions for mid-market to enterprise clients. Leverage your experience to navigate intricate deals, mentor peers, and take on leadership opportu...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $135K *

Shape the future of healthcare communication by empowering teams to deliver impactful medical content, fostering strategic client relationships, and leading innovative cross-functional collaborations...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $135K *

Join a team that shapes innovative medical strategies, driving excellence in healthcare content. Collaborate with experts, cultivate client relationships, and inspire teams to elevate project outcomes...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Join a team that's dedicated to precision and efficiency in accounting. Lead the monthly close process, manage reconciliations, and collaborate cross-functionally in a fast-paced environment, ensuring...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$130K - $160K *

Join a dynamic team to drive integrated marketing strategies that enhance brand visibility and support business growth through innovative campaigns, digital activation, and thought leadership across m...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$300K *

Manage the complete sales cycle by identifying leads, building relationships, and closing deals efficiently while collaborating with cross-functional teams to enhance customer success and drive the ad...

RemoteRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$150K *

Empower a high-performing sales team to drive adoption of innovative medical solutions. Collaborate with healthcare professionals, develop strategic business plans, and ensure compliance while achievi...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Lead the charge in driving strategic account management and renewal success. Oversee a high-performing team, enhance customer relationships, and optimize processes to achieve exceptional retention and...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $120K *

Champion the development of high-quality program materials and deliverables, enhancing effectiveness in complex specialty markets. Collaborate with teams to ensure project success through strong manag...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Help us drive financial success by leveraging analytics and strategic insights to support high-growth initiatives. Engage with cross-functional teams to optimize budgets, forecast, and enhance our rep...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$90K - $170K *

Join a team that's driving strategic sales in TMS, WMS, and SaaS solutions. Lead initiatives to achieve sales targets, develop customer relationships, and promote innovative technology offerings while...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Transportation

$91K - $142K *

Transform corporate engagement by connecting Marketing & Communications with key governance processes. Lead risk and control programs while crafting executive narratives that drive strategic alignment...

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$92K - $128K *

Manage and analyze financial matters for assigned properties, ensuring accurate reporting and compliance. Collaborate with various departments to support budgeting, audits, and financial statements, w...

Yesterday

  •   Less than 5 years exp.  •   Real Estate & Construction

$145K - $242K *

Grow your career with a dynamic role focused on community engagement and HIV prevention. Collaborate cross-functionally to drive strategic initiatives, enhance outreach, and deliver impactful solution...

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$175K - $215K *

Pioneer your career by leading financial planning and analysis, driving strategic initiatives, and guiding cross-functional collaboration to impact organizational success at a high level of decision-m...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Enterprise Technology

$110K - $130K *

Lead the optimization of cross-pillar workflows, ensuring technical soundness and operational effectiveness. Collaborate with engineering and product teams to enhance product adoption and drive measur...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$79K - $93K *

Lead a dynamic team of Sales Support Administrators, driving sales support processes and ensuring compliance with BSI procedures. Collaborate with stakeholders to enhance team performance and deliver...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$164K - $282K *

Empower innovation by leading regulatory strategies for product launches and compliance. Drive excellence in cross-functional collaboration, ensuring timely approvals and market readiness for orthopae...

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.