Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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$102K - $179K *

Elevate healthcare outcomes by leading value analysis initiatives that enhance clinical quality, operational efficiency, and cost savings. Collaborate with diverse teams to implement evidence-based so...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $110K *

Elevate your career by driving business growth in Public Safety. Own the full sales cycle, engage with key stakeholders, and leverage your expertise to enhance 911 Emergency Communications Centers acr...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$85K - $110K *

Join a team that's driving growth in the manufacturing sector by applying innovative sales strategies. You'll engage with customers, develop new business, and lead initiatives to enhance branch sales...

3 weeks ago

  •   Less than 5 years exp.  •   Energy & Utilities

$150K - $300K *

Join us to lead technology operations across manufacturing and lab sites, ensuring reliable, secure, and scalable solutions. Collaborate with cross-functional teams to align technology with business p...

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$125K - $175K *

Join a dynamic team to drive financial strategy and insights, ensuring sound decision-making across high-priority projects. Collaborate with leadership to optimize performance and support innovative p...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$95K - $115K *

Accelerate business growth by managing relationships with brokers and agents, focusing on Chubb's Small Commercial and Middle Market products. Drive new client acquisition and achieve performance metr...

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $95K *

Lead the charge in expanding market presence by owning the full sales cycle, driving revenue growth, and solving complex financial challenges for SMEs through innovative fintech solutions. Collaborate...

Yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

$80K - $95K *

Transform the US SME market by owning the full sales cycle, driving revenue growth, and delivering clear business value through innovative financial technology solutions for diverse clients...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

$80K - $100K *

Unlock potential by building your own client portfolio in the logistics sector. Engage in prospecting, relationship management, and innovative technology use to drive sales and achieve uncapped earnin...

Yesterday

  •   Less than 5 years exp.  •   Transportation

$100K - $120K *

Shape your career by building a client portfolio in transportation and logistics. Drive sales through innovative technology, manage relationships, and enjoy uncapped earning potential in a supportive...

6 days ago

  •   Less than 5 years exp.  •   Transportation

$110K - $188K *

Drive business development and deepen relationships with financial advisors in the RIA channel. Serve as a trusted advisor, leveraging investment acumen to enhance product adoption and sales execution...

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$157K - $197K *

Unlock potential by driving revenue growth through new customer acquisition and market expansion. This strategic role focuses on building executive relationships, executing targeted penetration strate...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Champion your career by leading a dynamic team in client processing, enhancing service quality, and driving operational improvements. Collaborate with stakeholders to ensure exceptional client experie...

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$120K - $145K *

Elevate procurement excellence by leading strategy development for indirect categories. Collaborate cross-functionally to optimize costs and supplier relationships while ensuring compliance and govern...

Reposted 2 days ago

  •   8 - 10 years exp.  •   Food & Beverages

$110K - $130K *

Lead and coordinate business development, customer relations, and quality management activities to enhance private pay services, ensuring operational excellence and growth in a dynamic healthcare envi...

6 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$120K - $135K *

Champion the growth of partnerships in the public safety sector, harnessing your sales expertise to cultivate high-level relationships, create member benefits, and drive innovative solutions that enha...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$120K - $160K *

Engage in shaping business systems by managing the roadmap, translating needs into specs, and enhancing infrastructure for agile delivery. Collaborate with diverse teams to ensure data integrity and e...

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$83K - $155K *

Contribute to the success of hygienic sensors by owning product strategy, collaborating with engineering, and driving market insights into actionable requirements. Lead product launches and manage lif...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$200K - $240K *

Provide executive-level technical leadership for a WealthTech platform, shaping engineering vision and strategy. Lead high-performing teams, drive platform modernization, and ensure compliance while c...

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$255K - $402K *

Lead and innovate within the Outsourcing team, driving strategic partnerships and operational excellence in drug metabolism and bioanalytical development, while managing a diverse team to enhance scie...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$95K - $110K *

Elevate your career by partnering with enterprise-level prospects, leveraging your consultative selling skills to drive revenue growth and navigate complex procurement processes for transformative dig...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$100K - $150K *

Unlock potential by driving revenue growth through strategic sales initiatives in data center security solutions. Collaborate with cross-functional teams to develop customer relationships and achieve...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$100K - $120K *

Unlock new business opportunities in life sciences by driving strategic account growth. Engage with stakeholders to identify needs, shape solutions, and close complex projects in automation and manufa...

3 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$230K - $345K *

Transform clinical trial management by leading early-phase oncology programs. Drive strategic vision, operational excellence, and cross-functional collaboration to ensure timely, budget-compliant exec...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Grow your career by leading a customer-centric team dedicated to operational excellence and safety in service delivery. Collaborate with leadership to achieve business goals and enhance customer relat...

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Transportation

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.