Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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$100K - $120K *

Transform data into actionable insights by leading analytics solutions that drive decision-making and improve performance. Collaborate across functions to establish trusted metrics and promote self-se...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$139K - $209K *

Elevate your career by leveraging scientific expertise to drive sales growth in the life sciences sector. Collaborate with customers to align their research needs with innovative solutions, fostering...

Pennsylvania, USRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$50K - $150K *

Accelerate progress at driving new business and shaping client success through full sales cycle management, relationship building, and innovative solutions that enhance operations and foster growth in...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$164K - $225K *

Champion enterprise transformation by leading cross-functional initiatives, ensuring governance and execution quality across value-streams. Collaborate with leaders to drive measurable outcomes and bu...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$148K - $313K *

Unlock potential by serving as a strategic advisor to enterprise clients, guiding them in architecting AI-first solutions within the Life Sciences sector, while driving internal initiatives and enhanc...

RemoteRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $130K *

Manage and lead field-based medical teams, ensuring client delivery and team performance while fostering scientific engagement and program growth. Collaborate with cross-functional teams to achieve st...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $157K *

Shape the future of enterprise sales by driving innovative strategies, fostering relationships, and generating revenue through a proactive approach in a dynamic, remote environment focused on large mu...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Telecommunications & Hardware

$110K - $130K *

Develop and execute national sales strategies to drive growth in industrial networking and cybersecurity. Build relationships, identify opportunities, and deliver tailored solutions to clients in crit...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Technical Services

$102K - $179K *

Join a team that's dedicated to enhancing healthcare value through strategic analysis. Lead initiatives that optimize clinical outcomes and operational efficiency while collaborating with diverse stak...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$102K - $179K *

Elevate healthcare outcomes by leading value analysis initiatives that enhance clinical quality, operational efficiency, and cost savings. Collaborate with diverse teams to implement evidence-based so...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $110K *

Elevate your career by driving business growth in Public Safety. Own the full sales cycle, engage with key stakeholders, and leverage your expertise to enhance 911 Emergency Communications Centers acr...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$85K - $110K *

Join a team that's driving growth in the manufacturing sector by applying innovative sales strategies. You'll engage with customers, develop new business, and lead initiatives to enhance branch sales...

3 weeks ago

  •   Less than 5 years exp.  •   Energy & Utilities

$150K - $300K *

Join us to lead technology operations across manufacturing and lab sites, ensuring reliable, secure, and scalable solutions. Collaborate with cross-functional teams to align technology with business p...

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$125K - $175K *

Join a dynamic team to drive financial strategy and insights, ensuring sound decision-making across high-priority projects. Collaborate with leadership to optimize performance and support innovative p...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$95K - $115K *

Accelerate business growth by managing relationships with brokers and agents, focusing on Chubb's Small Commercial and Middle Market products. Drive new client acquisition and achieve performance metr...

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $95K *

Lead the charge in expanding market presence by owning the full sales cycle, driving revenue growth, and solving complex financial challenges for SMEs through innovative fintech solutions. Collaborate...

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$80K - $95K *

Transform the US SME market by owning the full sales cycle, driving revenue growth, and delivering clear business value through innovative financial technology solutions for diverse clients...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$80K - $100K *

Unlock potential by building your own client portfolio in the logistics sector. Engage in prospecting, relationship management, and innovative technology use to drive sales and achieve uncapped earnin...

Yesterday

  •   Less than 5 years exp.  •   Transportation

$100K - $120K *

Shape your career by building a client portfolio in transportation and logistics. Drive sales through innovative technology, manage relationships, and enjoy uncapped earning potential in a supportive...

6 days ago

  •   Less than 5 years exp.  •   Transportation

$110K - $188K *

Drive business development and deepen relationships with financial advisors in the RIA channel. Serve as a trusted advisor, leveraging investment acumen to enhance product adoption and sales execution...

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$157K - $197K *

Unlock potential by driving revenue growth through new customer acquisition and market expansion. This strategic role focuses on building executive relationships, executing targeted penetration strate...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Champion your career by leading a dynamic team in client processing, enhancing service quality, and driving operational improvements. Collaborate with stakeholders to ensure exceptional client experie...

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$120K - $145K *

Elevate procurement excellence by leading strategy development for indirect categories. Collaborate cross-functionally to optimize costs and supplier relationships while ensuring compliance and govern...

Reposted 2 days ago

  •   8 - 10 years exp.  •   Food & Beverages

$110K - $130K *

Lead and coordinate business development, customer relations, and quality management activities to enhance private pay services, ensuring operational excellence and growth in a dynamic healthcare envi...

6 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$120K - $135K *

Champion the growth of partnerships in the public safety sector, harnessing your sales expertise to cultivate high-level relationships, create member benefits, and drive innovative solutions that enha...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.