Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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$85K - $95K *

Join a dynamic team as a strategic People Business Partner, advising leaders on talent strategy, change management, and employee relations. Drive engagement and organizational growth while fostering a...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$161K - $273K *

Transform client relationships and drive revenue growth by leveraging deep industry expertise and consultative selling skills. Collaborate with teams to deliver tailored payment solutions and lead com...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$200K - $300K *

Advance your career by engaging homeowners directly to design and sell remodeling projects. Utilize your construction knowledge and sales skills to create tailored solutions, manage appointments, and...

3 weeks ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$180K - $230K *

Grow your career with a leadership role overseeing global operations, focusing on strategy development, performance management, and cross-department collaboration to drive operational excellence and i...

RemoteRemote

Reposted 1 week ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$85K - $90K *

Accelerate revenue growth by developing tailored sales strategies, nurturing client relationships, and leveraging market insights. Collaborate with teams to optimize processes and mentor junior member...

6 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$120K - $150K *

Lead the charge in advancing our mission through strategic fundraising and resource development. Collaborate with leadership to foster a culture of philanthropy, ensuring sustainable funding and impac...

Yesterday

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$160K - $185K *

Join a dynamic team to drive growth by engaging mid-market employers, managing the full sales cycle, and fostering long-term partnerships. Collaborate with cross-functional teams to deliver innovative...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $140K *

Transform your career by leading product development initiatives that enhance enterprise reporting and analytics. Collaborate with cross-functional teams to deliver high-quality solutions that meet bu...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$126K - $211K *

Elevate customer relationships by driving growth within oncology practices. Utilize a consultative approach to align solutions with client objectives and collaborate with internal teams to enhance bus...

RemoteRemote

Reposted today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$183K - $220K *

Lead strategic initiatives for Integrated Delivery Networks and health systems, optimizing patient access and formulary adoption. Build executive relationships and drive clinical integration to enhanc...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$140K - $175K *

Shape the future of market intelligence by leveraging AI and research to uncover customer insights, drive strategic decisions, and enhance collaboration across teams. Play a pivotal role in advancing...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$101K - $204K *

Unlock potential by leading the redesign of People Operations processes. Drive operational excellence through strategic assessments, workflow mapping, and implementation of innovative solutions that e...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $171K *

Transform your career by leading a dynamic team in the HVAC service industry. Drive sales growth, enhance customer satisfaction, and foster a culture of excellence while managing operations and develo...

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$190K - $250K *

Engage with cloud partners to drive co-sell strategies, enhance pipeline growth, and foster relationships. Act as a liaison between internal sales teams and cloud partners, ensuring alignment and exec...

Today

  •   5 - 7 years exp.  •   Information Technology

$125K - $150K *

Lead the charge in enterprise sales by hunting new logos within the Life Sciences sector. Build relationships with Salesforce partners to enhance co-selling opportunities while managing your own pipel...

RemoteRemote

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$215K - $239K *

Create transformative customer experiences and drive revenue growth across North America by leading market solutions teams, coaching talent, and navigating organizational change with clarity and effec...

United StatesRemote

Reposted 4 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$62K - $103K *

Join a team that's dedicated to maximizing revenue through strategic account management, focusing on military bases. Drive sales growth by understanding customer needs and implementing effective solut...

Today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$100K - $120K *

Optimize logistics operations to enhance efficiency and profitability. Lead cross-functional teams in dispatch, fleet management, and customer service to drive improvements, reduce costs, and elevate...

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$175K - $200K *

Lead the charge in developing integrated media strategies and client partnerships across pharmaceutical and life sciences accounts, driving business growth and ensuring exceptional delivery and client...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Partner with us to enhance client relationships and drive growth. In this role, you'll manage a diverse portfolio, ensuring customer retention and identifying new opportunities while collaborating wit...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Consumer Technology

$120K - $165K *

Pioneer in leading a dynamic team of Solution Engineers, optimizing multi-discipline datacenter solutions across data protection, storage, compute, and networking. Drive collaboration to shape industr...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Information Technology

$175K - $210K *

Shape the future of precision medicine by managing executive relationships and driving enterprise-wide adoption of molecular diagnostics. Collaborate across teams to implement strategic initiatives an...

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$180K - $220K *

Shape strategic partnerships in precision medicine by managing executive relationships and driving enterprise-wide adoption of molecular diagnostics. Collaborate across teams to ensure successful impl...

RemoteRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$177K - $221K *

Champion global revenue accounting policies and lead technical assessments across U.S. and international markets, ensuring compliance with U.S. GAAP and SEC reporting while collaborating with regional...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$146K - $178K *

Shape the future of biopharma by leading commercial strategy engagements, guiding clients through critical launch decisions, and delivering evidence-based recommendations to drive success in a dynamic...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.