Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
Global Strategic Partnership Director
$150K - $180K *
Transform global partner strategies to drive revenue and market share through innovative go-to-market models, collaborating with key stakeholders to establish impactful partnerships and optimize sales...
5 days ago
$95K - $115K *
Oversee product line management by developing strategies, optimizing supply chain efficiency, and nurturing key supplier relationships to enhance overall business growth and performance...
Reposted 2 weeks ago
Executive Director, Patient Solutions Operations
$160K - $200K *
Lead the operational execution of a patient support program, ensuring high-quality service delivery and compliance. Drive strategic planning, team development, and continuous improvement initiatives t...
4 days ago
Executive Director, Patient Solutions Operations
$160K - $190K *
Drive operational excellence in patient support programs, enhancing access and outcomes through strategic leadership, compliance, and team development. Oversee key functions to ensure a patient-center...
5 days ago
Technical Sales Manager, Genomics (Mid-Atlantic Region)
$115K - $145K *
Transform client engagement by driving growth in life sciences sales through strategic account management, innovative solutions, and effective teamwork, focusing on NGS and dPCR portfolios to maximize...
4 weeks ago
Senior Product Marketing Manager
$120K - $145K *
Elevate your career by leading strategic product marketing initiatives, managing high-impact projects, and collaborating cross-functionally to drive value propositions in enterprise technology, includ...
3 weeks ago
Director, Life Sciences - Oligo & Peptide Market Segment Leader
$150K - $180K *
Drive strategic growth in the Oligo & Peptide market by leading a cross-functional team. Enhance market capture, foster industry relationships, and establish CRB as a thought leader while developing t...
3 weeks ago
National Sales Manager, Medical Education
$98K - $183K *
Join a team that's driving growth in Medical Education by leading B2B sales initiatives. You'll develop strategies, manage a high-performing sales team, and collaborate with cross-functional partners...
6 days ago
National Sales Executive - Default Services
$100K - $120K *
Help us drive revenue growth by developing strategic sales plans and building executive partnerships in the mortgage servicing industry. Leverage your expertise to manage complex sales cycles and enha...
2 weeks ago
$125K - $150K *
Drive operational excellence by leading regional managers, building teams, and enhancing client relationships. Oversee portfolio performance, support strategic initiatives, and foster a culture of acc...
Reposted 1 week ago
$125K - $150K *
Empower operational excellence by overseeing regional property managers, driving client satisfaction, and innovating team performance while supporting strategic initiatives and engaging stakeholders a...
Reposted 1 week ago
$150K - $180K *
Elevate client relationships by managing strategic Tier 1 accounts, driving revenue growth, and ensuring customer satisfaction. Collaborate cross-functionally to develop account strategies and deliver...
3 weeks ago
Sales Director, Data Platform Team (West Coast)
$160K - $200K *
Unlock potential by driving strategic sales initiatives and expanding our customer base in the data analytics sector. Collaborate with cross-functional teams while engaging executives to showcase inno...
3 weeks ago
Director of Strategic Sales - Charlotte, NC
$125K - $150K *
Lead the charge in driving B2B sales growth by prospecting and closing new clients. Collaborate with cross-functional teams to optimize strategies and deliver compelling presentations, ensuring a stro...
1 week ago
$350K - $450K *
Accelerate growth by leading a top-tier sales team to drive innovative cloud contact center solutions, ensuring customer transformation through strategic enterprise engagements and robust pipeline man...
3 weeks ago
$80K - $100K *
Accelerate business growth by owning the full sales cycle and expanding strategic partnerships with enterprise retailers. Leverage insights to consistently exceed revenue targets and drive impactful s...
Reposted 1 week ago
Account Executive - South East
$250K - $300K *
Elevate cybersecurity solutions by driving sales cycles, building relationships with CISO's, and consistently meeting quotas through effective prospecting and outreach in a dynamic enterprise environm...
Reposted 3 days ago
Sr. Director, Data Platform (Houston, TX Preferred OR United States - Remote)
$200K - $255K *
Lead the charge in shaping a cutting-edge data platform that enhances data architecture, governance, and operational effectiveness, driving cross-product adoption and ensuring alignment with business...
Reposted 3 weeks ago
$210K - $250K *
Accelerate success by leading our BEC Legal Systems business, driving strategic direction, P&L ownership, and operational excellence to enhance customer satisfaction and market leadership in B2B SaaS...
Reposted 1 week ago
Executive Director, Field Operations Strategy & Excellence
$246K - $332K *
Transform the future of field operations by leading strategic initiatives that enhance commercial effectiveness and drive measurable impact across customer-facing teams. Collaborate with cross-functio...
5 days ago
Institutional Sales Director - Growth Market
$100K - $157K *
Transform the nonprofit retirement plan landscape by driving sales growth, managing a robust pipeline, and fostering strong intermediary relationships. Leverage innovative solutions to meet client nee...
3 weeks ago
Vice President, Product Marketing
$240K - $290K *
Unlock your potential by leading product marketing strategy, shaping market insights, defining customer profiles, and influencing go-to-market approaches. Drive cross-functional collaboration to eleva...
Reposted 4 days ago
Regional Sales Director - Oklahoma City
$180K - $215K *
Elevate regional sales performance by leading a high-impact team, executing strategic launches, and fostering key customer relationships in a dynamic, fast-paced environment. Drive accountability and...
4 days ago
Senior Manager, Direct Sales - United States
$200K - $265K *
Champion growth by leading a high-performing sales team to drive new customer acquisition and expand market presence. Utilize AI-driven strategies and structured sales frameworks to achieve consistent...
1 week ago
$130K - $160K *
Drive growth as an integral part of our Commercial Sales Team, managing key health system relationships and closing complex deals, while collaborating across departments and shaping the product roadma...
3 weeks ago
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.