Explore $100K+ Jobs in North Carolina

Discover professional opportunities across North Carolina with Ladders, a job site focused on roles paying $100,000 or more. From established business centers to growing regional markets, the state offers opportunities for experienced professionals seeking their next career move.

North Carolina’s Professional Job Markets

Charlotte is a major hub for banking, financial services, and corporate leadership. The Research Triangle—including Raleigh, Durham, and Chapel Hill—has opportunities across technology, life sciences, healthcare, education, and research. Other cities and regions also support careers in manufacturing, logistics, energy, and professional services.

Roles for Experienced Professionals

Browse senior and specialized openings in areas such as software and technology, finance, healthcare, engineering, sales, operations, and executive leadership. Listings vary by employer and location, so review each posting for its responsibilities, qualifications, work arrangement, and compensation details.

Find Your Next North Carolina Opportunity

Use Ladders to explore vetted professional jobs with salaries of $100,000 or more. Search by job title, employer, or location, and compare openings across North Carolina to find roles that align with your experience and career goals.

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$96K - $128K *

Unlock potential by managing procurement processes, ensuring vendor compliance, and facilitating bid preparations. Collaborate with project teams to optimize purchasing strategies and maintain operati...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Technical Services

$125K - $150K *

Join a dynamic team to lead executive searches across multiple functions, driving the full-cycle recruitment process for senior leadership roles. Collaborate with executives to refine strategies and e...

US-AnywhereRemote

Today

  •   8 - 10 years exp.  •   Enterprise Technology

$150K *

Join a dynamic team to engage C-level executives in AI governance, driving enterprise sales in finance and biotech. Utilize your expertise in consultative selling to close complex, high-value deals an...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$114K - $171K *

Lead the charge in advancing enterprise clinical trial contracting operations. Oversee negotiations, enhance process efficiency, and guide a dedicated team to ensure compliance and accelerate research...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Transform the future of software development by architecting multi-agent systems and automation frameworks. Join a diverse team dedicated to pioneering cutting-edge AI applications in a collaborative...

US-AnywhereRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$126K - $171K *

Lead the charge in transforming HR operations by harnessing AI solutions, collaborating closely with teams to innovate and streamline workflows, enhance employee relations, and drive operational excel...

US-AnywhereRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Business Services

$74K - $87K *

Transform customer experiences by leading Unanet ERP implementations, ensuring successful configurations and training for Government Contracting clients. Manage multiple projects, driving adoption and...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$160K - $190K *

Elevate our talent acquisition by architecting AI-driven recruiting workflows. Lead the design, deployment, and optimization of innovative solutions that enhance hiring efficiency and candidate experi...

US-AnywhereRemote

6 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$74K - $102K *

Explore and enhance HR systems by supporting configuration, maintenance, and improvements. Collaborate with stakeholders to resolve issues and drive system enhancements in a dynamic environment focuse...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Technical Services

$140K - $200K *

Join a team that's redefining digital experiences for millions. As a Senior Product Designer, you'll lead innovative design across web and mobile platforms, integrating AI tools to enhance user journe...

Reposted yesterday

  •   5 - 7 years exp.  •   Staffing

$110K - $130K *

Grow your career with a leading STEM talent solutions provider driving new client acquisition. Leverage expertise and collaboration to excel in business development across various industry verticals a...

2 weeks ago

  •   5 - 7 years exp.  •   Staffing

$72K - $103K *

Empower your career by supporting strategic business management initiatives. Collaborate with teams to analyze data, implement process improvements, and optimize operations, ensuring effective decisio...

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$100K - $120K *

Explore future opportunities in enterprise sales aimed at large K-12 districts, fostering meaningful relationships and driving impactful solutions in the EdTech space, leveraging your experience in co...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $105K *

Lead software development projects, ensuring timely delivery and alignment with business goals. Collaborate with cross-functional teams to manage all phases of the SDLC, from planning to post-launch s...

1 week ago

  •   Less than 5 years exp.  •   Staffing

$266K - $360K *

Champion legal excellence by advising on complex commercial agreements, guiding partner ecosystems, and shaping global marketing strategies. Lead a high-performing team to drive legal support for inno...

5 days ago

  •   11 - 15 years exp.  •   Enterprise Technology

$94K - $151K *

Join a team that's driving innovation in Orthopaedics by leveraging data analytics and AI to enhance commercial effectiveness. Collaborate across functions to build trusted datasets, deliver insights...

US-AnywhereRemote

5 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$78K - $117K *

Elevate patient care by applying your skills in diagnostic and therapeutic services for diverse communication and swallowing disorders, engaging in multidisciplinary teams, and ensuring consistency in...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$93K - $148K *

Unlock financial insights by owning forecasting processes and collaborating across GTM functions to drive informed decisions. Utilize strong analytical skills and business judgment to influence leader...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$100K - $120K *

Engage in proactive recruitment to attract top-performing Account Executives in the non-QM mortgage sector. Blend talent acquisition with market intelligence for strategic sourcing and relationship-bu...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$110K - $130K *

Champion the talent acquisition function, driving senior-level searches from start to finish. Collaborate closely with hiring managers to align recruitment with business goals, ensuring a streamlined...

US-AnywhereRemote

6 days ago

  •   5 - 7 years exp.  •   Media

$135K - $150K *

Champion growth by developing strategies and managing health plan sales to exceed revenue goals. Build impactful customer relationships and lead cross-functional initiatives within a defined territory...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$200K - $230K *

Elevate your career by leading the design and optimization of HR operations. Drive compliance, enhance payroll accuracy, and build scalable processes that support a growing organization. Collaborate c...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $120K *

Partner with us to drive revenue growth and strategic account management across a diverse portfolio. You'll own the full sales cycle, collaborate with cross-functional teams, and build lasting relatio...

US-AnywhereRemote

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $110K *

Grow your career with a role focused on talent acquisition strategies across diverse engineering and operational fields while fostering candidate relationships and delivering exceptional hiring soluti...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Staffing

$80K - $110K *

Unlock potential by supporting Federal clients through data analysis, process documentation, and project coordination. Collaborate with teams to deliver actionable insights and drive effective solutio...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    Listings may include senior and specialized roles in technology, finance, healthcare, engineering, sales, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Which North Carolina cities have professional job opportunities?question toggle

    Opportunities can be found in Charlotte, Raleigh, Durham, Chapel Hill, and other North Carolina cities and regions. Search by location to see current openings.

  • Does Ladders list jobs paying $100,000 or more?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Check individual postings for compensation information and role details.

  • How can I search for jobs in North Carolina?question toggle

    Search Ladders by job title, employer, or North Carolina location, then review listings for qualifications, responsibilities, work arrangement, and compensation.