Explore $100K+ Jobs in North Carolina

Discover professional opportunities across North Carolina with Ladders, a job site focused on roles paying $100,000 or more. From established business centers to growing regional markets, the state offers opportunities for experienced professionals seeking their next career move.

North Carolina’s Professional Job Markets

Charlotte is a major hub for banking, financial services, and corporate leadership. The Research Triangle—including Raleigh, Durham, and Chapel Hill—has opportunities across technology, life sciences, healthcare, education, and research. Other cities and regions also support careers in manufacturing, logistics, energy, and professional services.

Roles for Experienced Professionals

Browse senior and specialized openings in areas such as software and technology, finance, healthcare, engineering, sales, operations, and executive leadership. Listings vary by employer and location, so review each posting for its responsibilities, qualifications, work arrangement, and compensation details.

Find Your Next North Carolina Opportunity

Use Ladders to explore vetted professional jobs with salaries of $100,000 or more. Search by job title, employer, or location, and compare openings across North Carolina to find roles that align with your experience and career goals.

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$90K - $115K *

Elevate operational excellence by managing contracts for accuracy and compliance. Collaborate with cross-functional teams to streamline processes and enhance deal velocity while minimizing risks and e...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$73K - $105K *

Join a dynamic team to lead and scale Managed Payroll services, shaping operations and enhancing customer experience. Drive team development, streamline processes, and leverage technology to deliver e...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$100K - $120K *

Manage external communications initiatives to elevate brand visibility, drive strategic marketing plans, and foster key relationships across media and stakeholders to strengthen market positioning and...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$60K - $129K *

Transform healthcare delivery as a remote RN Case Manager, assessing and coordinating care for members. Leverage your clinical expertise to enhance wellness outcomes and navigate complex health needs...

US-AnywhereRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$85K - $142K *

Empower environmental compliance by managing air, water, and waste programs. Collaborate with regulatory agencies and support EHS initiatives to ensure adherence to federal, state, and local regulatio...

Today

  •   Less than 5 years exp.  •   Business Services

$80K - $95K *

Empower business success by collaborating with cross-functional teams to enhance operations, gather requirements, and implement IT solutions that align with strategic goals. Drive improvements in orde...

US-AnywhereRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Shape strategic initiatives and operational excellence by leading district programs, ensuring alignment with educational goals, and fostering collaboration across departments to enhance student achiev...

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$164K - $201K *

Drive strategic engagement with key defense contractors while cultivating impactful relationships at all levels, creating competitive plans, and leading mutual opportunities to enhance market presence...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$130K - $154K *

Shape the future of finance by owning financial planning and analysis for Consumer operations, driving efficiency, and enhancing resource allocation through data-driven insights across a dynamic growt...

US-AnywhereRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $90K *

Champion project success by managing timelines, resources, and stakeholder communication. Drive seamless implementation experiences while collaborating with cross-functional teams to deliver value-dri...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$88K - $105K *

Transform customer engagement by delivering exceptional presentations and events that showcase innovative retail technology. Collaborate with cross-functional teams to create impactful experiences tha...

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $145K *

Transform enterprise service delivery by leading cross-center operations, enhancing efficiency, and ensuring high-quality IT services across multiple locations. Drive initiatives that improve performa...

US-AnywhereRemote

1 week ago

  •   11 - 15 years exp.  •   Information Technology

$100K - $120K *

Unlock potential by managing sales for managed services contracts, fostering long-term relationships with key clients, driving revenue growth within assigned accounts, and exceeding performance goals...

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$102K - $154K *

Advance customer success by managing complex escalations, driving cross-functional improvements, and enhancing workflows. Lead high-severity issue resolution while fostering a structured, customer-cen...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$150K - $180K *

Innovate your career as a Senior Legal Counsel, providing strategic legal guidance across commercial, corporate, and compliance matters while supporting complex transactions and risk management in a d...

4 days ago

  •   8 - 10 years exp.  •   Staffing

$110K - $130K *

Architect solutions to enhance DevOps teams' security by managing pre-sales technical support, conducting product demos, and serving as a subject matter expert in CI/CD integrations and workflows. Eng...

US-AnywhereRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$112K - $132K *

Empower operations by providing real-time support for trading and clearing systems across multiple exchanges. Troubleshoot issues, coordinate resolutions, and drive enhancements to ensure seamless cli...

US-AnywhereRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$110K - $130K *

Shape the future of enterprise automation by partnering with clients to develop, implement, and enhance customized automations on Kognitos’ platform, transforming dynamic business processes into effic...

US-AnywhereRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$73K - $110K *

Transform patient care by leading clinical initiatives, engaging in collaboration and governance, while delivering evidence-based nursing services in a supportive, dynamic environment focused on excel...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$92K - $110K *

Deliver strategic leadership and operational oversight to enhance decision-making processes within the Veterans Health Administration's EHRM, ensuring effective collaboration and communication across...

US-AnywhereRemote

Today

  •   11 - 15 years exp.  •   Healthcare

$80K - $95K *

Engage with clients by nurturing relationships, identifying growth opportunities, and providing exceptional support. Leverage your expertise in account management to drive customer satisfaction and re...

US-AnywhereRemote

4 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$85K - $100K *

Empower financial innovation by integrating enterprise applications and ensuring seamless data movement. Collaborate with teams to enhance ERP projects, troubleshoot integrations, and support data mig...

US-AnywhereRemote

1 month ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$152K - $259K *

Shape the future of global People Operations by leading a dynamic team to innovate and streamline processes, enhancing the employee experience through technology and strategic partnerships across func...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$104K - $174K *

Lead the charge in optimizing materials management strategies, driving process improvements, and enhancing supply chain efficiency. Collaborate with teams to implement lean principles and achieve busi...

5 days ago

  •   5 - 7 years exp.  •   Business Services

$191K - $306K *

Drive L&E strategies across the USA, ensuring compliance in all employment matters while managing litigation, union negotiations, and organizational risk. Collaborate with global leaders to advance ef...

3 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    Listings may include senior and specialized roles in technology, finance, healthcare, engineering, sales, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Which North Carolina cities have professional job opportunities?question toggle

    Opportunities can be found in Charlotte, Raleigh, Durham, Chapel Hill, and other North Carolina cities and regions. Search by location to see current openings.

  • Does Ladders list jobs paying $100,000 or more?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Check individual postings for compensation information and role details.

  • How can I search for jobs in North Carolina?question toggle

    Search Ladders by job title, employer, or North Carolina location, then review listings for qualifications, responsibilities, work arrangement, and compensation.