Explore $100K+ Jobs in North Carolina

Discover professional opportunities across North Carolina with Ladders, a job site focused on roles paying $100,000 or more. From established business centers to growing regional markets, the state offers opportunities for experienced professionals seeking their next career move.

North Carolina’s Professional Job Markets

Charlotte is a major hub for banking, financial services, and corporate leadership. The Research Triangle—including Raleigh, Durham, and Chapel Hill—has opportunities across technology, life sciences, healthcare, education, and research. Other cities and regions also support careers in manufacturing, logistics, energy, and professional services.

Roles for Experienced Professionals

Browse senior and specialized openings in areas such as software and technology, finance, healthcare, engineering, sales, operations, and executive leadership. Listings vary by employer and location, so review each posting for its responsibilities, qualifications, work arrangement, and compensation details.

Find Your Next North Carolina Opportunity

Use Ladders to explore vetted professional jobs with salaries of $100,000 or more. Search by job title, employer, or location, and compare openings across North Carolina to find roles that align with your experience and career goals.

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$110K - $130K *

Shape the future of procurement by leading strategic sourcing initiatives, enhancing vendor relationships, and driving financial transparency. Collaborate across teams to streamline processes and leve...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$79K - $118K *

Join a team that's dedicated to providing exceptional patient care in a fast-paced orthopedic unit. As a compassionate RN, you'll coordinate comprehensive care, ensuring safety and quality outcomes fo...

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$99K - $137K *

Optimize Workday solutions by leading configuration, testing, and enhancements. Collaborate with HR teams to translate business needs into effective system designs while ensuring data integrity and go...

US-AnywhereRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Energy & Utilities

$125K - $150K *

Empower your career by owning performance management and total rewards. Collaborate with C-suite leaders to drive compliance and leverage technology, ensuring impactful HR processes that enhance team...

US-AnywhereRemote

6 days ago

  •   5 - 7 years exp.  •   Media

$68K - $103K *

Join us to oversee post-award grants and clinical trial management, ensuring compliance and efficiency in financial reporting and transactions while collaborating with investigators and administrative...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$125K - $150K *

Drive new business growth by owning strategic accounts in the automotive sector. Collaborate with key stakeholders, navigate complex organizations, and leverage insights to shape our go-to-market stra...

US-AnywhereRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$110K - $145K *

Drive full-cycle recruitment efforts by innovating sourcing strategies and collaborating with senior leaders to attract senior talent across sales and business operations, while ensuring a seamless, e...

US-AnywhereRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$95K - $115K *

Elevate your career by leading strategic sourcing initiatives for high-value nuclear projects. Drive procurement activities, manage supplier relationships, and ensure compliance while collaborating ac...

3 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$95K - $115K *

Join us to lead strategic sourcing initiatives for high-value nuclear projects. Drive procurement activities, manage supplier relationships, and ensure compliance while collaborating with cross-functi...

1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$150K - $180K *

Transform growth strategies for military decision-making by leading market initiatives, conducting research, and nurturing relationships with key stakeholders in the U.S. Navy and defense sectors to e...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$79K - $118K *

Empower healthcare delivery by providing essential clinical administrative support, coordinating patient care, and collaborating with multidisciplinary teams to ensure optimal patient outcomes and saf...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$85K - $150K *

Own the mid-market provider segment by driving complex sales conversations and closing meaningful deals that enhance compliance programs for healthcare organizations. Build and manage your pipeline wh...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$106K - $159K *

Lead the charge in clinical and administrative leadership for a dynamic 36-bed medical-surgical unit, ensuring high-quality, patient-centered care while fostering staff development and a collaborative...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Oversee the resolution of complex technical issues, mentor analysts, and drive continuous improvement initiatives to enhance service reliability and user experience within the service desk environment...

1 week ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$79K - $170K *

Drive global site activation strategies, ensuring efficient project execution and compliance. Collaborate with cross-functional teams to enhance operational effectiveness and support clinical trial su...

US-AnywhereRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$125K - $150K *

Lead the charge in transforming public sector consulting by guiding organizations through digital transformation and ERP implementations, while managing high-impact teams and fostering client relation...

US-AnywhereRemote

5 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$92K - $154K *

Drive your career by developing integrated power conversion solutions for diverse industries. Leverage your technical expertise to create innovative applications and enhance business opportunities in...

US-AnywhereRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Business Services

$170K - $245K *

Champion the design and deployment of AI-driven systems, integrating diverse data sources to create intelligent agents and workflows. This hands-on role demands expertise in applied AI and production...

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$120K - $165K *

Transform your career by leading revenue cycle consulting projects, managing junior staff, and driving operational improvements while building strong client relationships. Leverage your expertise in h...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$120K - $160K *

Elevate business growth by driving strategic sales initiatives across key sectors. Leverage your network to build relationships and develop tailored solutions, while collaborating with partners to enh...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$105K - $150K *

The Senior Consultant, NetSuite is responsible for leading full-cycle NetSuite implementation projects, from discovery to deployment, while ensuring excellent customer service. This role involves coll...

US-AnywhereRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$85K - $117K *

Make your mark at a vital role where you'll enhance patient independence through personalized occupational therapy, fostering rehabilitation and functional improvement in the comfort of their homes wh...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$85K - $117K *

Unlock your potential as an Occupational Therapist, providing vital in-home rehabilitation and support for patients to regain mobility and independence while collaborating closely with healthcare team...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$200K - $250K *

Elevate client partnerships by solving complex business challenges. Seek out and establish new connections while fostering long-term relationships to drive success and become a trusted advisor in the...

US-AnywhereRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$85K - $100K *

Oversee complex workers' compensation claims, from investigation to resolution, ensuring compliance and effective communication with all stakeholders while managing significant exposures across multip...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    Listings may include senior and specialized roles in technology, finance, healthcare, engineering, sales, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Which North Carolina cities have professional job opportunities?question toggle

    Opportunities can be found in Charlotte, Raleigh, Durham, Chapel Hill, and other North Carolina cities and regions. Search by location to see current openings.

  • Does Ladders list jobs paying $100,000 or more?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Check individual postings for compensation information and role details.

  • How can I search for jobs in North Carolina?question toggle

    Search Ladders by job title, employer, or North Carolina location, then review listings for qualifications, responsibilities, work arrangement, and compensation.