Explore HR Leader Jobs

Discover senior human resources opportunities for experienced professionals ready to shape workforce strategy and lead people-focused teams. Ladders features vetted HR leadership jobs with salaries of $100,000 or more, including roles at organizations seeking strategic, results-oriented leaders.

What HR Leaders Do

HR leaders guide the programs and policies that help organizations attract, develop, and retain talent. Depending on the role and company, responsibilities may include workforce planning, recruiting strategy, compensation and benefits, employee relations, learning and development, organizational design, and HR operations. They also advise executives on people-related decisions and help align talent initiatives with business goals.

Common HR Leadership Titles

Roles in this category may include Chief Human Resources Officer (CHRO), Chief People Officer, Vice President of Human Resources, HR Director, Head of People, and senior leaders in talent acquisition, total rewards, or people operations. Titles and scope vary by organization, industry, and company size.

Skills and Experience Employers Seek

Employers often look for a strong record leading HR teams and initiatives, sound judgment, clear communication, and the ability to connect people strategy with business outcomes. Experience with employment practices, change management, talent development, HR technology, and data-informed decision-making may also be valuable. Requirements differ across roles, so review each listing for details.

Find Your Next HR Leadership Role

Browse vetted HR leader opportunities on Ladders and explore positions with salaries of $100,000 or more. Compare responsibilities, qualifications, and compensation information to find roles aligned with your experience and career goals.

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$174K - $374K *

Unlock potential by leading medical management initiatives remotely, supporting member needs and optimizing clinical services for optimal care. Leverage your expertise in Orthopedic Spine or Neurosurg...

RemoteRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$232K - $348K *

Lead the charge in oncology pharmacology, managing scientific teams to drive drug discovery from early stages through regulatory approval while ensuring alignment across cross-functional teams...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Join a team that's dedicated to advancing clinical research through statistical expertise. Collaborate with medical professionals to design, analyze, and report on clinical studies, ensuring complianc...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$207K - $295K *

Partner with us to lead clinical trials in late-stage oncology, ensuring safety and data integrity while collaborating with global teams to drive innovative development strategies and enhance patient...

Markham, ONRemote

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $165K *

Build and manage clinical stewardship operations, driving client success through effective program implementation and cross-functional collaboration. Leverage clinical expertise to enhance client rela...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$180K - $195K *

Join a dynamic team to lead and manage clinical trials, ensuring timely execution and compliance. Collaborate with cross-functional partners and vendors to drive operational success in immunology rese...

Boston, MARemote

4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$103K - $120K *

Advance your career by reviewing and revising scientific claims for dietary supplements. Collaborate with cross-functional teams to ensure compliance and support product development while managing mul...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Food & Beverages

$78K - $168K *

Play a key role in delivering personalized in-home health evaluations, building valuable relationships while ensuring patients receive the comprehensive care they need in a comfortable setting...

Wichita, KSRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$180K - $220K *

Drive clinical excellence by providing medical expertise across therapeutic areas, ensuring safety and integrity in clinical trials. Collaborate with project teams and senior management to enhance cli...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$137K - $195K *

Unlock potential by driving sales and business development for innovative bioprocessing solutions. Collaborate with key accounts and internal teams to enhance customer satisfaction and market presence...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$98K - $164K *

Champion client success by leading post-sale implementations and ensuring ongoing account performance. Collaborate with cross-functional teams to translate client needs into actionable insights, drivi...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$160K - $200K *

Champion regulatory strategy and submissions for clinical-stage radiopharmaceutical programs. Collaborate cross-functionally to ensure compliance and quality in regulatory communications, while leadin...

Cambridge, MARemote

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$174K - $215K *

Lead a dynamic team to drive business performance in hematology/oncology, focusing on metastatic breast cancer. Develop strategies for patient access and treatment, ensuring compliance and collaborati...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$90K - $180K *

Elevate our Fresh inventory flow strategy by optimizing processes and building strong partnerships. Drive analytics and execution across teams to enhance cost efficiency, speed, and availability, ensu...

Bentonville, ARRemote

Reposted today

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$80K - $95K *

Elevate healthcare by educating providers on genetic testing initiatives through virtual platforms. Collaborate cross-functionally to enhance diagnostic strategies and advocate for stakeholder educati...

Denver, CORemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Grow your career with a dynamic role focused on executing brand strategies, managing territory sales, and building strong customer relationships to enhance patient-centered outcomes and achieve financ...

Trenton, NJRemote

4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$170K - $195K *

Lead the charge in global regulatory submissions, managing U.S. INDs and ex-U.S. CTAs. Collaborate cross-functionally to develop strategies, ensure compliance, and drive timely approvals in a fast-pac...

San Francisco, CARemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$190K - $238K *

Lead the transformation of patient experiences in mental health care by shaping marketing strategies that drive acquisition, activation, and retention. Collaborate across teams to enhance messaging an...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$177K - $221K *

Lead the development and execution of global CMC regulatory strategies to support clinical trials and market applications, ensuring compliance with regulatory requirements throughout the product lifec...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$108K - $135K *

Unlock your potential by driving sales success in specialty biopharmaceuticals. Collaborate with healthcare professionals to enhance patient outcomes and execute strategic business plans within primar...

RemoteRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Shape the future of healthcare by leading complex implementations across provider and payor organizations. Drive project success through collaboration, strategic planning, and innovative solutions whi...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Join a team that's redefining DME resupply operations by leading a global, remote call center. Drive revenue growth, optimize performance, and ensure compliance while managing a diverse workforce to e...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$115K - $192K *

Elevate operational excellence by leading process design and transformation initiatives. Drive automation, quality management, and continuous improvement to enhance client data operations and ensure s...

RemoteRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$119K - $150K *

Shape the future of enterprise application integrations by leading technical design and implementation for Finance, Accounting, and Supply Chain projects, collaborating with cross-functional teams to...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$102K - $136K *

Empower your career by designing and delivering scalable software solutions in a dynamic environment. Collaborate with cross-functional teams to enhance healthcare supply chain products using modern t...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What does an HR leader do?question toggle

    An HR leader sets or guides people strategy and oversees areas such as talent acquisition, employee relations, compensation, development, and HR operations. The exact responsibilities depend on the organization and role.

  • What job titles are included in HR leadership?question toggle

    Common titles include Chief Human Resources Officer, Chief People Officer, VP of Human Resources, HR Director, Head of People, and senior roles focused on talent, total rewards, or people operations.

  • What qualifications are typically required for HR leader jobs?question toggle

    Requirements vary, but employers commonly seek substantial HR experience, leadership ability, sound knowledge of people practices, and a record of connecting HR initiatives to organizational goals. Some positions may require specific industry or functional expertise.

  • What is the typical salary for an HR leader?question toggle

    Compensation varies based on seniority, location, industry, company size, and responsibilities. Ladders focuses on vetted jobs paying $100,000 or more; review individual listings for available salary details.

  • Where can I find HR leader jobs paying $100,000 or more?question toggle

    Explore HR leadership listings on Ladders to find vetted opportunities with salaries of $100,000 or more and compare roles by responsibilities, qualifications, and compensation.