Explore $100K+ Jobs in South Dakota

Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.

South Dakota career opportunities

South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.

Where to find jobs

Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.

Find the right role on Ladders

Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.

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1,000+

Account Director Jobs in South Dakota

Sort By: Relevance

$180K - $190K *

Deliver innovative solutions by acquiring Fortune 500 clients, leading complex sales cycles, and building executive relationships. Drive value through AI insights and strategic partnerships, ensuring...

United StatesRemote

2 days ago

  •   11 - 15 years exp.  •   Enterprise Technology

$150K - $180K *

Join a team that's driving growth by managing major enterprise accounts. You'll foster relationships, navigate complex sales cycles, and lead strategic initiatives to expand our footprint in the cyber...

United StatesRemote

1 month ago

  •   11 - 15 years exp.  •   Technical Services

$165K *

Join us to lead a dynamic Sales Development team, driving pipeline growth through strategic outbound and inbound initiatives. Collaborate with cross-functional teams to enhance performance and leverag...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$124K - $186K *

Transform enterprise growth by driving GitLab's AI-powered DevSecOps solutions adoption and expansion through strategic account management and trusted client partnerships in the Seattle area...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $155K *

Unlock potential by leading strategic partnerships in Creative Software Licensing. Drive growth through innovative deals, build relationships with developers, and shape the future of digital tools for...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Media

$125K - $180K *

The Enterprise Account Executive at Elicit will be responsible for managing the full sales cycle for key opportunities in complex enterprise environments, particularly in life sciences, biotech, and p...

RemoteRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$173K - $288K *

Empower growth and relationships in a strategic role focused on managing key accounts. Drive customer satisfaction and revenue retention through strategic collaboration and consultative selling within...

RemoteRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Transform your career by driving enterprise solutions forward. Leverage your SaaS sales expertise to build strong client relationships, effectively manage opportunities, and deliver impactful solution...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$100K - $120K *

Transform your career by driving new business growth and client success in a dynamic remote environment. Leverage your sales expertise to build strategic partnerships and exceed revenue targets while...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$135K - $198K *

Unlock strategic growth by cultivating partnerships in the Beverage & Brewing sector. Collaborate with senior stakeholders to enhance customer success through innovative solutions, driving long-term v...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Business Services

$125K - $200K *

Unlock your potential by driving new business growth in a dynamic sales role. Engage with customers, build relationships, and develop strategic plans to expand market presence across North and South C...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$107K - $145K *

Drive growth by identifying and securing new business opportunities in risk management and medical education. Collaborate with teams to develop proposals, manage sales pipelines, and ensure alignment...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$194K - $266K *

Champion patient engagement strategies by leading a dynamic team focused on optimizing recruitment and retention across clinical trials. Drive performance, enhance collaboration, and ensure successful...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$232K - $290K *

Optimize revenue generation by leading Sales and Revenue Operations, driving performance across customer-facing teams, and fostering a culture of excellence through strategic initiatives and cross-fun...

United StatesRemote

Reposted 3 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$110K - $130K *

Drive enterprise sales by managing the full cycle from prospecting to closing, building relationships with executive stakeholders, and delivering impactful business cases to secure multi-year agreemen...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Transportation

$90K - $115K *

Elevate your career by leading innovative social media programs that connect healthcare clients with their audiences. Drive strategic content development and manage cross-functional teams to ensure im...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $170K *

Champion growth by engaging complex life sciences accounts, driving value through strategic relationships. Navigate multifaceted deals with precision, collaborating across teams for impactful sales su...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $130K *

Drive the success of Abacum implementation projects, managing end-to-end delivery while collaborating with sales and partners to ensure client satisfaction and value realization on the platform...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$125K - $135K *

Join a team that's driving growth in the life insurance and annuity market. Leverage your expertise to build strategic relationships, manage the full client lifecycle, and align solutions with client...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Drive growth by selling our innovative platform to financial institutions. Manage complex, multi-stakeholder sales cycles, guiding clients through their AI journey while exceeding annual quotas in a c...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$240K - $330K *

Transform the GTM Systems landscape by leading strategy, architecture, and operations. Drive efficiency across Sales, Marketing, and Customer Success through innovative solutions and data governance...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$80K - $95K *

Join our team to drive sales across a defined portfolio, engaging healthcare organizations with our innovative solutions. Own the sales cycle from prospecting to closing while collaborating with inter...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Join a dynamic field sales team to drive growth in the aerospace and defense sector, focusing on innovative software solutions for unmanned aerial systems, while fostering relationships and achieving...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$139K - $157K *

Transform client partnerships by leading innovative commerce strategies across major retail platforms. Drive growth through integrated marketing, operational excellence, and creative solutions, ensuri...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$100K - $120K *

Drive growth by owning the full sales cycle in B2B SaaS. Generate pipeline, run demos, and navigate negotiations to close net-new business, all while collaborating with leadership in a dynamic, fast-p...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000-plus jobs are available in South Dakota?question toggle

    Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.

  • Which South Dakota cities have professional job opportunities?question toggle

    Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.

  • How can I find high-paying jobs in South Dakota?question toggle

    Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.

  • Do South Dakota jobs listed on Ladders all pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.