Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From positions in Jackson and the Gulf Coast to opportunities in communities across the state, find roles that match your experience, skills, and career goals.

Professional Opportunities Across Mississippi

Mississippi employers hire experienced professionals across industries such as healthcare, finance, manufacturing, technology, energy, and business operations. Available roles and compensation vary by employer, location, and qualifications, so review each listing for details about responsibilities, salary, and requirements.

Search in Mississippi Cities and Regions

Find opportunities in major employment centers including Jackson, Gulfport, and Southaven, as well as other Mississippi communities. Use location and job-title filters to focus your search, and consider remote or hybrid listings when available.

Find a Role That Fits Your Career

Compare opportunities by seniority, specialty, and work arrangement. Keep your résumé current, highlight measurable results, and tailor your application to the qualifications in each listing. Ladders helps professionals explore vetted jobs with salaries of at least $100,000.

Start Your Mississippi Job Search

Browse Mississippi jobs on Ladders and take the next step toward a professional opportunity aligned with your expertise and compensation goals. Listings change frequently, so check back for new roles.

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$129K - $190K *

Empower cross-functional teams by providing expert legal counsel on product development, privacy, and compliance in the ad-tech space. Collaborate closely with engineering, marketing, and product team...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$135K - $150K *

Elevate your career by leading product operations, enhancing processes, and driving AI adoption. Collaborate with cross-functional teams to optimize product delivery and analytics, ensuring seamless c...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$61K - $122K *

Optimize product delivery by bridging business needs and technical teams, leading requirement gathering, defining user stories, and ensuring alignment with stakeholders to enhance Epic EHR capabilitie...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$149K - $202K *

Transform the HCP launch landscape by leading innovative marketing initiatives for a groundbreaking treatment in Sjögren's disease. Collaborate cross-functionally to engage healthcare professionals an...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Drive revenue growth by managing key K-12 client relationships, identifying new business opportunities, and achieving sales targets. Leverage strategic sales expertise to foster long-term partnerships...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$95K - $115K *

Champion impactful Amazon advertising strategies, driving growth through data-driven insights and hands-on campaign management. Collaborate with clients and internal teams to optimize performance acro...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$227K - $313K *

Elevate your career by leading strategic reimbursement initiatives, optimizing revenue cycles, and collaborating with key stakeholders to enhance patient access and billing processes in a dynamic heal...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$100K - $120K *

Engage with senior stakeholders to enhance R&D efficiency in life sciences. Drive proposals, develop strategies, and ensure quality oversight while building networks to support business development an...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $195K *

Join a dynamic team as you cultivate investor relationships and drive capital growth. Leverage your LIHTC expertise to expand our investor base, manage key accounts, and contribute to impactful afford...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$120K - $180K *

Drive the growth of our partner channel by leading recruitment and strategy for ISVs, VARs, and ISOs in the payments landscape. Collaborate across teams to enhance partner relationships and expand rev...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$187K - $257K *

Empower transformation initiatives by leading enterprise projects, managing stakeholder relationships, and driving strategic outcomes. Collaborate with diverse teams to define program strategies and e...

RemoteRemote

Yesterday

  •   8 - 10 years exp.  •   Healthcare

$280K - $350K *

Transform the Enterprise sales landscape by leading a high-performing team of Account Executives, driving revenue growth, and fostering collaboration across departments to maximize customer success an...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Enterprise Technology

$85K - $105K *

Transform virtual resettlement services by leading a national portfolio that enhances access for refugees. Oversee strategy, implementation, and compliance while fostering partnerships and innovative...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$100K - $120K *

Join a dynamic team to drive sales solutions and foster strong customer relationships within the restaurant sector, enhancing product offerings and customer satisfaction through strategic engagement a...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $135K *

Join a team that's shaping the future of digital services for Veterans. As a Senior Software Engineer, you'll design and maintain scalable applications, collaborate with cross-functional teams, and me...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $230K *

Unlock potential by driving strategic sales initiatives for major clients. Engage in lead origination, account management, and growth strategies in the Retail and CPG sectors, leveraging industry insi...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$73K - $95K *

Join a team that's dedicated to ensuring financial accuracy and compliance. In this pivotal role, you'll manage key accounting processes, support audits, and provide insights that drive informed decis...

RemoteRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$122K - $182K *

Unlock potential by leading enterprise-scale data and AI solutions, modernizing actuarial processes, and driving cloud-native transformations. Collaborate with stakeholders to enhance decision-making...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$144K - $191K *

Unlock potential by leading the Automated Operations capability within Member Services. Oversee AI support experiences, enhance team productivity, and drive continuous improvement to elevate member in...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $250K *

Transform financial services by leading complex banking operations and technology projects. Collaborate with clients to enhance performance, drive innovation, and shape a new practice within a dynamic...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$120K - $155K *

Champion business development and growth of custom adhesive solutions across North America, focusing on the Bus, Truck, Rail, and Specialty Vehicle markets. Drive customer acquisition and strategic ac...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Business Services

$150K - $180K *

Drive strategic planning and operational excellence for a dynamic Marketing & Communications team. Own budgeting, resource management, and cross-functional partnerships while leading initiatives that...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Healthcare

$160K - $185K *

Transform client value and operational performance by leveraging data-driven insights, financial modeling, and strategic solutions. Collaborate across teams to enhance service delivery and drive measu...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$110K - $130K *

Join a team that's dedicated to creating impactful medical education content for healthcare providers and patients. Collaborate closely with scientific and account teams to deliver high-quality materi...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Champion strategic sales transformation by leveraging data and insights to drive growth, optimize operations, and enhance decision-making across a global sales organization. Collaborate with leadershi...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What types of jobs can I find in Mississippi on Ladders?question toggle

    You can explore professional opportunities across fields such as healthcare, finance, manufacturing, technology, energy, and business operations. Roles and availability vary over time.

  • Are Mississippi jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional jobs that pay $100,000 or more. Check each listing for compensation details, qualifications, and other job-specific information.

  • Where in Mississippi can I search for jobs?question toggle

    Search across the state, including employment centers such as Jackson, Gulfport, and Southaven. You can use location filters to narrow results.

  • How can I find remote or hybrid jobs based in Mississippi?question toggle

    Use available work-arrangement filters or review listing details to identify remote and hybrid opportunities. Availability depends on the employer and role.

  • How do I improve my chances of getting hired for a Mississippi job?question toggle

    Tailor your résumé to the role, emphasize relevant experience and measurable outcomes, and ensure you meet the listed qualifications before applying.