Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
$110K - $130K *
Lead the charge in overseeing high-impact projects, driving strategic initiatives, and fostering strong customer relationships while ensuring alignment with business objectives and delivering measurab...
Reposted 1 week ago
$120K - $145K *
Lead the charge in driving growth for our System Integration business across North America. You'll identify and close high-value opportunities, foster strategic customer relationships, and collaborate...
Reposted today
Territory Sales Manager - Mid America Region
$100K - $120K *
Accelerate progress at the forefront of the electric utility industry by leading sales and customer relationships for innovative power solutions. Drive growth, forge partnerships, and deliver exceptio...
4 days ago
$112K - $128K *
Drive business development for large-scale podcast and broadcast campaigns, fostering client relationships and achieving revenue growth. Collaborate with cross-functional teams to deliver innovative a...
2 weeks ago
Managing Director - Market Development & Revenue Growth (Insurance Growth Platforms)
$180K - $220K *
Lead the charge in driving growth across insurance platforms by building strategic alliances, developing executive relationships, and executing market strategies to enhance revenue and expand opportun...
1 week ago
$150K - $200K *
Bring your expertise to lead sales strategies and customer development across NCC and VIS product lines, driving profitable growth and enhancing commercial processes while fostering collaboration with...
Reposted today
Managing Director, Food & Beverage Investment Banking
$213K - $445K *
Advance strategic initiatives in Food & Beverage investment banking by cultivating senior-level relationships, executing complex transactions, and providing expert advisory services to clients, drivin...
3 weeks ago
Sales Account Executive (Utah)
$165K - $185K *
Empower your sales career by building relationships with healthcare providers, driving revenue growth and championing AI-based medical solutions to transform cancer care for patients and physicians...
Reposted 6 days ago
Executive Director, Strategic Accounts
$246K - $332K *
Transform healthcare by leading national strategic account management efforts. Drive partnerships with key institutions, enhance patient care, and foster cross-functional collaboration to achieve comm...
4 days ago
$110K - $130K *
Join a team that's transforming software sales by driving technical solutions and creative outreach. Lead the full sales cycle and collaborate cross-functionally to deliver unique insights and busines...
Reposted 1 week ago
Inside Sales Account Executive
$80K - $95K *
Drive your career with a dynamic sales role focused on the full customer journey, from prospecting to closing, in a fast-paced cybersecurity environment. Maximize your impact and earnings while buildi...
2 weeks ago
Senior Regional Sales Consultant
$95K - $115K *
Transform healthcare engagement by building relationships with HCPs through digital interactions and telephone conversations, promoting products, and achieving sales goals while ensuring compliance wi...
1 week ago
$150K - $180K *
Lead the charge in building and scaling strategic partnerships to drive revenue growth. Oversee the entire partner lifecycle, from selection to enablement, ensuring successful collaboration and measur...
2 weeks ago
$210K - $250K *
Transform the product marketing landscape by leading go-to-market strategies for cutting-edge AI and cloud solutions. Collaborate cross-functionally to craft compelling narratives that resonate with c...
1 week ago
Channel Manager, North America
$100K - $120K *
Lead the charge in developing and executing channel strategies to drive growth, onboard high-performing partners, and enhance relationships with distributors in the life sciences sector...
1 week ago
Key Account Director, Mortgage
$125K - $150K *
Accelerate growth by driving strategic sales initiatives and expanding key accounts. Leverage your expertise in complex sales cycles to secure new business and enhance existing relationships within th...
2 weeks ago
Enterprise Account Executive - West
$130K - $140K *
Transform enterprise partnerships by leading complex sales cycles, aligning stakeholders, and driving impactful solutions for large educational organizations. Collaborate with executives to enhance op...
1 week ago
Regional Sales Director - Richmond
$180K - $215K *
Lead the charge in driving regional sales success through strategic execution, team leadership, and cross-functional collaboration. Foster strong customer relationships and ensure alignment with corpo...
6 days ago
Director, Corporate Sales - Consulting
$170K - $230K *
Accelerate growth by leading a high-performing sales team in the Professional Services & Consulting sector. Drive strategy, performance, and revenue while fostering a culture of collaboration and exce...
1 week ago
Field Regional Sales Manager - FL/GA
$110K - $130K *
Shape the future of K-12 literacy by leading a dynamic sales team, driving growth, and building lasting partnerships with educators. Leverage your expertise to develop strategies that enhance educatio...
2 weeks ago
Enterprise Sales 1 - Providers (East)
$93K - $113K *
Empower healthcare providers by driving enterprise sales strategies, managing client relationships, and leveraging cross-functional teams to enhance patient experience and operational effectiveness in...
2 weeks ago
$220K - $260K *
Join a team that's redefining engineering leadership by leveraging AI to enhance productivity and streamline processes. Drive hands-on technical initiatives while managing a lean, high-output team foc...
3 days ago
Product Manager - Customer Data Exchange
$86K - $138K *
Lead the strategy and execution of enterprise data exchange products, ensuring secure and standardized data sharing. Collaborate with stakeholders to drive interoperability and maximize business value...
2 weeks ago
Regional Client Director, West
$156K - $234K *
Transform strategic healthcare partnerships by leading complex account initiatives, driving growth, and enhancing customer engagement across diverse Integrated Delivery Networks and Group Purchasing O...
4 days ago
Regional Sales Director - Birmingham
$180K - $215K *
Drive regional sales success by leading launch execution, building high-performing teams, and fostering customer relationships. Collaborate cross-functionally to achieve strategic goals in a fast-pace...
5 days ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.