Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

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$150K - $180K *

Drive new logo acquisition and revenue growth in the healthcare sector by leading complex sales processes, building executive relationships, and collaborating with cross-functional teams to deliver ta...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$295K - $325K *

Drive strategic sales leadership across the Western US, translating brand vision into effective field execution. Build and sustain a high-performing team while collaborating cross-functionally to achi...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Elevate your career by driving growth through strategic partnerships in the TSD ecosystem. This role focuses on recruiting and managing Trusted Advisors, generating opportunities, and collaborating wi...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$135K - $146K *

Innovate strategic partnerships and drive revenue growth in NTN and IoT sectors. Cultivate relationships with global carriers, negotiate agreements, and identify new business opportunities to establis...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$132K - $221K *

Drive enterprise-wide legal support for global contracting activities, focusing on procurement and technology transactions. Collaborate with cross-functional teams to manage risks and ensure complianc...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Transform your career by driving strategic partnerships in healthcare. Leverage your extensive relationships within benefits consulting to influence and expand business opportunities while collaborati...

United StatesRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Hospitality & Recreation

$80K - $95K *

Champion a dynamic team environment where you’ll manage logistics, mentor staff, and enhance customer experiences. Embrace challenges and drive growth in a fast-paced setting, all while contributing t...

3 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$125K - $150K *

Elevate your career by leading strategic initiatives in Electrical product management, driving growth through analytics, vendor partnerships, and cross-functional collaboration to optimize profitabili...

Today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$121K - $163K *

Grow strategic client relationships while driving financial outcomes through expert management. Lead teams to optimize client experiences and foster adoption of tailored solutions in a dynamic institu...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$121K - $163K *

Accelerate progress at an institutional client level by fostering deep relationships, driving client satisfaction, and leading integrated teams to tailor financial solutions while managing a complex p...

Reposted 1 month ago

  •   5 - 7 years exp.  •   Finance & Insurance

$121K - $163K *

Advance client relationships by guiding integrated teams to drive positive outcomes and strategic growth in a complex institutional environment. Leverage analytics to identify client needs and enhance...

Reposted 1 month ago

  •   5 - 7 years exp.  •   Finance & Insurance

$190K - $280K *

Transform talent acquisition by leading a global team to enhance recruiting efficiency, drive strategy, and leverage AI for measurable improvements across diverse markets while ensuring compliance and...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Join a dynamic team to drive partner growth through strategic prospecting, negotiations, and training. Leverage your expertise to optimize sales performance and ensure seamless integration for new par...

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$202K - $250K *

Champion data-driven decision-making by leading the development of integrated analytics and reporting strategies. Drive operational efficiency and financial performance through innovative data solutio...

United StatesRemote

3 days ago

  •   11 - 15 years exp.  •   Healthcare

$150K - $180K *

Drive enterprise safety leadership by developing strategies, systems, and talent to enhance risk management and prevent injuries. Collaborate with operations to embed safety practices across projects...

3 weeks ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$150K - $180K *

Join us to lead strategic marketing and communications initiatives that enhance visibility and engagement. Drive impactful relationships and elevate brand reputation while managing a high-performing t...

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$172K - $287K *

Join us to shape the future of pharmacy by leading product strategy and innovation. Drive growth and commercialization for a diverse portfolio of healthcare technology solutions, influencing enterpris...

RemoteRemote

Reposted 1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Lead the charge in developing compelling scientific content and strategic initiatives. Collaborate with cross-functional teams to enhance medical communications across therapeutic areas, driving engag...

Today

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Join a team that's shaping innovative scientific communication strategies. This role combines advanced content development with strategic leadership across therapeutic areas, engaging directly with cl...

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Partner with us to drive strategic healthcare marketing initiatives. Lead client relationships, oversee peer-to-peer programs, and mentor team members to ensure compliance and achieve results while fo...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$180K - $220K *

Shape the future of Endpoint Security by leading product strategy, driving innovation, and ensuring financial growth. Collaborate cross-functionally to enhance product performance and market positioni...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$100K - $150K *

Build strategic partnerships and drive revenue growth by managing high-potential accounts. Collaborate with internal teams to enhance partner engagement and achieve production targets while fostering...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$105K - $120K *

Help us drive sales growth and enhance community partnerships by leading a dynamic sales team focused on expanding market share and improving patient registrations in the healthcare sector...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$200K - $235K *

Transform public safety operations by driving growth through strategic sales and relationship-building with fire departments and agencies. Own the sales cycle, deliver impactful demos, and collaborate...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$200K - $225K *

Unlock growth by leading strategic partnerships in the CDMO sector. Drive sales, nurture client relationships, and collaborate across teams to enhance market presence and customer satisfaction. Your e...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.