Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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1,000+

Vice President, Sales Jobs in Missouri

Sort By: Relevance

$130K - $163K *

Shape the future of AI in our organization as a strategic leader driving enterprise-wide adoption and integration of AI technologies, enhancing productivity and delivering measurable results through i...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $120K *

Elevate your career by managing high-end senior living projects, ensuring quality, budget, and safety standards are met while fostering strong client relationships and leading a dedicated project team...

4 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$120K - $145K *

Help us shape the future of financial planning and analysis in a dynamic SaaS environment. Drive forecasting, budgeting, and KPI reporting while collaborating across teams to support growth and M&A in...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$100K - $120K *

Champion new business growth by leveraging your consultative sales expertise to build relationships with utility and public sector clients, driving revenue and delivering tailored solutions that meet...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$80K - $90K *

Lead the charge in managing comprehensive accounting functions for self-insurance groups, ensuring accurate financial reporting, compliance with regulations, and effective budget management while coll...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$108K - $130K *

Unlock potential by leading compliance and consulting projects for multi-state alternative investment clients, managing client relationships, and mentoring staff in a dynamic team environment...

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$130K - $145K *

Champion client success by managing strategic partnerships with mid-sized enterprises. Drive measurable outcomes through relationship management, consultative problem-solving, and cross-functional col...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Unlock potential by leading tailored service solutions that drive client success. Collaborate with stakeholders to strategize and execute sales plans, ensuring exceptional engagement and delivering va...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$140K - $168K *

Lead the charge in maximizing the value of our multifamily portfolio across Colorado and Washington. Drive performance, streamline processes, and execute renovation strategies while collaborating with...

RemoteRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$115K - $125K *

Grow your career with us as you drive business development in the hospitality sector. Leverage your existing network to identify opportunities, close deals, and build lasting relationships while manag...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Real Estate & Construction

$110K - $130K *

Optimize project delivery by leading enterprise SaaS implementations for utility clients. Build strong client relationships, manage competing priorities, and ensure successful project outcomes across...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Energy & Utilities

$92K - $139K *

Drive exceptional customer success by managing a complex portfolio of Enterprise accounts, enhancing software value through strategic relationships and problem-solving. Influence industry revenue and...

RemoteRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Information Technology

$92K - $139K *

Drive customer success by managing a portfolio of enterprise accounts, ensuring optimal software utilization, and fostering strong relationships to enhance client satisfaction and revenue growth...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Information Technology

$170K - $230K *

Join us to drive the adoption of innovative satellite services for enterprise customers. You'll manage complex deals, execute strategic initiatives, and collaborate cross-functionally to enhance custo...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$125K - $157K *

Transform training programs by designing and implementing comprehensive sales and clinical training for orthopedic robotics, ensuring teams are equipped to excel in promoting robotic-assisted procedur...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Elevate operational excellence by leading project execution, fostering collaboration, and driving performance metrics. Engage with teams to ensure alignment and success from project inception to close...

3 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$140K - $176K *

Lead the charge in managing a high-performing PMO team, driving project success through strategic financial oversight, talent development, and cross-functional collaboration to enhance operational eff...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$192K - $334K *

Tackle complex healthcare M&A engagements, leading due diligence efforts, and collaborating with clients and teams to drive value. Manage multiple projects while utilizing your expertise to influence...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Legal & Accounting

$125K - $150K *

Drive your career with a pivotal role in Medical Informatics sales, focusing on building relationships, achieving revenue goals, and collaborating across teams to enhance customer experiences and expa...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$100K - $115K *

Champion integrated media strategies for pharmaceutical clients, driving engagement and measurable outcomes. Lead cross-functional teams to develop innovative solutions that address complex healthcare...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$71K - $115K *

Elevate customer success by serving as a strategic advisor for 75+ accounts, driving ROI through tailored solutions, proactive engagement, and cross-functional collaboration to ensure exceptional expe...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Join a team that's transforming businesses through data-driven strategies and hands-on execution. Drive client engagement in banking and wealth management, collaborating cross-functionally to deliver...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$125K - $150K *

Oversee retail commerce strategies across major platforms, driving revenue growth and optimizing ad spend. Collaborate with a seasoned team to solve complex retail challenges and mentor emerging speci...

2 weeks ago

  •   8 - 10 years exp.  •   Media

$105K - $115K *

Optimize medical device utilization in health systems by leveraging expertise in cardiovascular, interventional radiology, and general surgery. Collaborate with stakeholders to drive cost reduction an...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$140K - $170K *

Lead the charge in shaping portfolio-level product strategy for P&C insurance technology. Collaborate across multiple product lines to drive data-driven investment decisions and enhance overall portfo...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.