Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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$101K - $125K *

Unlock your potential by driving growth as a key player in a dynamic sales team. Collaborate with talented professionals to deliver tailored solutions and foster long-term client relationships, ultima...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Enterprise Technology

$140K - $200K *

Lead transformative sales enablement initiatives, driving team performance and productivity through strategic execution and innovative technology. Collaborate with leadership to enhance seller effecti...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$190K - $220K *

Innovate field operations by leading multi-market teams to ensure high-quality, safe installations of heat pumps and EV chargers across North America, driving performance and efficiency while fosterin...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Energy & Utilities

$385K - $400K *

Transform regional sales performance by leading a high-impact team, driving strategic growth, and utilizing best practices to meet ambitious quotas within a dynamic environment. Foster relationships a...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $95K *

Transform your sales career by engaging mid-sized businesses with cutting-edge insights. Drive data-driven decisions and close deals while leveraging innovative tools in a dynamic, supportive environm...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$175K - $210K *

Lead the charge in driving revenue growth by developing and executing innovative sales strategies, managing a high-performance team, and fostering key relationships in the industrial manufacturing sec...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$103K - $161K *

Drive strategic growth by establishing and nurturing key partnerships with Enterprise Claims carriers, ensuring service excellence and collaboration across internal teams to enhance business outcomes...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$150K - $180K *

Champion innovative sales strategies to secure $10M+ in federal revenue. Build relationships with DHS and federal agencies, develop operational use cases, and convert pilots into sustainable programs...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$150K - $180K *

Join us to drive strategic sales growth across key verticals in the South Central U.S. Lead complex enterprise sales cycles, engage with C-suite stakeholders, and develop a robust pipeline to achieve...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Join a dynamic team to lead and develop Channel AEs, driving growth in the Accountant sector. Collaborate cross-functionally to enhance partner success and exceed sales goals in a fast-paced environme...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$140K - $150K *

Shape the future of foodservice by leading strategic account growth with top chains. Drive market penetration, manage key relationships, and develop actionable plans to enhance profitability and expan...

RemoteRemote

5 days ago

  •   5 - 7 years exp.  •   Food & Beverages

$150K - $180K *

Elevate your career by driving efficiency and optimizing processes across Product & Engineering teams. Collaborate with cross-functional teams to implement Agile methodologies and enhance release mana...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Hospitality & Recreation

$200K - $225K *

Transform marketing strategies to drive growth and engagement across public and private sectors. Lead integrated marketing efforts, brand positioning, and customer marketing services while leveraging...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Education, Government & Non-Profit

$226K - $377K *

Lead the strategic management of renewals for key accounts, optimizing processes and enhancing customer relationships. Collaborate cross-functionally to drive successful outcomes while minimizing risk...

RemoteRemote

5 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $160K *

Elevate business growth by driving strategic sales initiatives across key sectors. Leverage your network to build relationships and develop tailored solutions, while collaborating with partners to enh...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$150K - $180K *

Help us drive revenue growth by leading the full sales cycle in the Digital Science sector, engaging with C-suite leaders and aligning solutions with enterprise strategies to enhance decision-making a...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$325K - $375K *

Lead the charge in driving revenue growth by building and mentoring a high-performing sales team in the Mid-Enterprise segment, focusing on customer acquisition and market penetration in a competitive...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$75K - $90K *

Elevate your career by driving B2B demand generation through new client acquisition and account growth. Build strong relationships with key stakeholders while leveraging AI to enhance your sales strat...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$90K - $110K *

Join a team that's driving sales growth in the home improvement sector. This role focuses on developing dealer partnerships, expanding market presence, and achieving sales objectives through strategic...

RemoteRemote

6 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Tackle new business acquisition by executing strategic sales processes to foster relationships and drive revenue growth in the healthcare IT sector. Collaborate cross-functionally while presenting sol...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Champion sales excellence by driving enterprise public safety solutions and cultivating strategic relationships, ensuring client satisfaction and operational improvement across medium to large governm...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$134K - $202K *

Transform your career by leading strategic initiatives that drive growth and innovation in the Fire & Safety sector. Collaborate with cross-functional teams to shape market strategies and ensure susta...

RemoteRemote

5 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$80K - $96K *

Drive impactful SaaS sales by owning the full sales cycle, from prospecting to closing. Cultivate value-driven partnerships with mid-market promotional product distributors while collaborating with a...

United StatesRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$150K - $161K *

Empower a dynamic team by leading outbound sales strategies, driving performance, and mentoring managers. Shape best practices and enhance pipeline creation to achieve ambitious goals in a fast-paced...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$100K - $120K *

Join a dynamic team as you drive sales growth by cultivating client relationships and executing strategic marketing initiatives. Leverage your consultative skills to provide tailored workforce solutio...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.