Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
VP, Labor & Public Sector Sales
$215K - $250K *
Pioneer your career by leading a dynamic sales team focused on Labor and Public Sector markets. Drive growth, mentor talent, and execute strategic initiatives to exceed revenue goals while building im...
3 weeks ago
$94K - $179K *
Lead the charge in managing complex projects from inception to completion, ensuring timely delivery and stakeholder satisfaction while guiding cross-functional teams through the project lifecycle...
1 week ago
Enterprise Sales Account Executive
$110K - $130K *
Unlock potential by leading strategic account management initiatives, driving customer satisfaction and revenue growth through effective relationship building and expansion strategies in a dynamic ent...
1 week ago
Senior Director, Regional Governance
$185K - $231K *
Unlock potential by leading regional service delivery, driving growth and operational excellence across multiple territories. Collaborate with diverse teams to enhance customer satisfaction and optimi...
2 weeks ago
$120K *
Grow your career with a leading windows company as you drive sales growth, cultivate accounts, and analyze market opportunities. Join a dynamic team focused on professional development and customer en...
2 weeks ago
$120K *
Accelerate your career as a Territory Sales Manager, driving growth through account development, market analysis, and strategic sales planning. Join a dynamic team focused on professional development...
2 weeks ago
$160K - $200K *
Shape the future of product strategy by leading a high-performing team, driving innovation, and ensuring alignment across operations and technology to deliver exceptional customer value and measurable...
3 weeks ago
Director of Field Operations, Cobrand Card
$125K - $150K *
Shape high-impact growth in retail partnerships by overseeing field operations, driving application volume, and enhancing point-of-sale conversion rates. Collaborate with teams to optimize strategies...
3 weeks ago
Senior Demand Generation Manager
$110K - $130K *
Unlock potential by leading innovative demand generation strategies that drive pipeline growth and market engagement. Collaborate across departments to optimize campaigns and mentor teams, ensuring al...
2 weeks ago
Regional Partner Director, NAMER
$190K - $240K *
Accelerate progress at strategic partnerships in the NAMER region by identifying, onboarding, and managing key partners. Drive revenue growth through collaboration, enablement, and relationship manage...
3 weeks ago
$87K - $157K *
Champion operational excellence by leading cross-functional teams to enhance business strategies and drive data-driven insights, ensuring quality and efficiency in regulated communications. Grow your...
Reposted today
$100K - $120K *
Lead the charge in expanding market presence for cutting-edge hospitality tech solutions across North America. Drive new business sales, build relationships, and collaborate with teams to achieve reve...
Reposted 6 days ago
Regional Sales Engineer, Central
$110K - $130K *
Join a team that's driving innovation in cybersecurity by leveraging your technical expertise to support enterprise sales. Engage with top-tier clients, guiding them through complex evaluations and de...
4 weeks ago
Vice President, Head of Service Practice
$200K - $275K *
Grow your career with a leadership role overseeing service strategy, delivery, and client relationships. Drive revenue growth and operational excellence across diverse industries while shaping transfo...
Reposted yesterday
Head of Field Sales Operations
$150K - $329K *
Drive operational excellence as you lead sales operations and business planning teams, translating data into strategic decisions that enhance revenue outcomes and foster collaboration across functions...
1 week ago
Senior Manager of Product Management
$125K - $150K *
Shape the future of healthcare technology by leading product management efforts, driving strategy, and delivering innovative data insights solutions. Collaborate with cross-functional teams to enhance...
3 weeks ago
Sr Manager, Technology Business Management
$120K - $145K *
Discover a pivotal leadership role in IT financial management, vendor governance, and technology optimization. Collaborate across departments to ensure technology investments yield value while managin...
Today
$105K - $112K *
Drive the success of a dynamic SDR team by shaping outbound sales strategies, mentoring talent, and optimizing lead generation processes. Collaborate with leadership to build a high-performing team th...
4 weeks ago
$109K - $129K *
Take ownership of product development in a dynamic, cross-functional team. Drive AI-assisted innovation from problem framing to launch, focusing on customer outcomes and strategic impact in a hyper-ag...
4 days ago
Business Development Manager - BTRS
$120K - $155K *
Champion business development and growth of custom adhesive solutions across North America, focusing on the Bus, Truck, Rail, and Specialty Vehicle markets. Drive customer acquisition and strategic ac...
2 weeks ago
Vice President, People Technology and Operations
$285K - $385K *
Champion transformative People technology and operations, driving AI and automation to enhance employee experiences. Lead strategic initiatives, optimize systems, and ensure data integrity while foste...
Today
$317K - $375K *
Take ownership of the pharmacy business, driving strategy, growth, and performance. Lead a skilled team, manage P&L, and ensure compliance while enhancing member experiences in a regulated environment...
Reposted today
$90K *
Transform your career by driving new business in public safety. Collaborate with internal teams to build relationships and innovate solutions for Fire, EMS, and Emergency Management agencies in a dyna...
3 weeks ago
$110K - $130K *
Join us to drive new customer acquisition for ERP solutions in discrete manufacturing. This full-cycle sales role requires building relationships, managing complex sales processes, and achieving reven...
1 week ago
District Sales Manager- Water Treatment
$90K - $110K *
Join a team that's dedicated to managing and expanding industrial water treatment accounts across Ohio and Indiana. Leverage your technical expertise and consultative selling skills to drive growth an...
1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.