Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$125K - $157K *

Transform training programs by designing and implementing comprehensive sales and clinical training for orthopedic robotics, ensuring teams are equipped to excel in promoting robotic-assisted procedur...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$125K - $150K *

Engage with co-founders and C-suite to lead executive recruiting efforts, build talent pipelines, and enhance hiring strategies. Drive high-impact searches while mentoring the recruiting team to eleva...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

$100K *

Lead the integration of acquired businesses, ensuring seamless transitions and customer satisfaction while managing project plans, risks, and cross-functional collaboration for successful outcomes...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Energy & Utilities

$90K - $105K *

Transform branch operations by leading a dynamic team, owning P&L, and driving sales while ensuring top-tier customer service and effective inventory management for sustained growth and success in the...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$130K - $160K *

Reimagine business improvement strategies as a senior contributor, leading high-impact initiatives across functions. Drive alignment, governance, and measurable outcomes while influencing stakeholders...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$192K - $334K *

Tackle complex healthcare M&A engagements, leading due diligence efforts, and collaborating with clients and teams to drive value. Manage multiple projects while utilizing your expertise to influence...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Legal & Accounting

$125K - $150K *

Drive your career with a pivotal role in Medical Informatics sales, focusing on building relationships, achieving revenue goals, and collaborating across teams to enhance customer experiences and expa...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$90K - $110K *

Join a team that's driving loan and deposit growth by providing strategic credit solutions for insurance agencies. Build trusted relationships, structure complex transactions, and collaborate with int...

United StatesRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $135K *

Champion a global HSEQ strategy, fostering compliance and quality across operational regions while developing a proactive safety culture and optimizing customer service delivery in the solar and stora...

United StatesRemote

Reposted 1 month ago

  •   5 - 7 years exp.  •   Energy & Utilities

$180K - $235K *

Drive growth by leveraging your consultative sales expertise to engage higher education leaders, aligning their needs with innovative research solutions while managing client relationships and achievi...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Business Services

$75K - $90K *

Join a team that's focused on driving revenue growth through strategic partnerships. You'll build lasting relationships, identify upsell opportunities, and collaborate with internal teams to deliver t...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$100K - $115K *

Champion integrated media strategies for pharmaceutical clients, driving engagement and measurable outcomes. Lead cross-functional teams to develop innovative solutions that address complex healthcare...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$95K - $120K *

Accelerate progress at the intersection of media and healthcare by leading integrated planning and strategy for pharmaceutical clients. Drive impactful engagement initiatives while mentoring a talente...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$71K - $115K *

Elevate customer success by serving as a strategic advisor for 75+ accounts, driving ROI through tailored solutions, proactive engagement, and cross-functional collaboration to ensure exceptional expe...

RemoteRemote

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$71K - $115K *

Transform customer experiences by driving success and satisfaction through proactive engagement, relationship management, and strategic guidance. Collaborate with clients to maximize their use of Serv...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$150K - $180K *

Shape the future of life sciences by leading a high-performing Product Management and Marketing team. Drive portfolio strategy, commercialization, and business growth while collaborating across functi...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Drive revenue growth by cultivating executive relationships, managing sales cycles, and articulating the transformative business value of innovative cloud solutions in the CAD industry...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Consumer Technology

$100K - $120K *

Lead the charge in managing premium client portfolios, guiding a skilled team to foster relationships and develop growth strategies across various verticals, maximizing both client success and agency...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $171K *

Transform customer engagement by leading automation and digital solutions. Drive cross-functional programs to enhance operational performance and value realization, collaborating with diverse teams to...

3 weeks ago

  •   8 - 10 years exp.  •   Transportation

$110K - $130K *

Join a team that's transforming businesses through data-driven strategies and hands-on execution. Drive client engagement in banking and wealth management, collaborating cross-functionally to deliver...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$95K - $115K *

Optimize customer success by driving engagement and retention, ensuring clients maximize value from services. Collaborate with teams to enhance the customer experience and advocate for their needs, co...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$105K - $115K *

Optimize medical device utilization in health systems by leveraging expertise in cardiovascular, interventional radiology, and general surgery. Collaborate with stakeholders to drive cost reduction an...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$140K - $170K *

Lead the charge in shaping portfolio-level product strategy for P&C insurance technology. Collaborate across multiple product lines to drive data-driven investment decisions and enhance overall portfo...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Unlock potential by driving growth in the US Higher Education market through consultative sales of innovative research solutions. Collaborate with teams to enhance customer relationships and achieve i...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $107K *

Join us to develop and manage educational resources that enhance Commercial readiness across clinical data solutions. Collaborate with cross-functional teams to translate complex information into acti...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.