Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$63K - $120K *

Drive revenue growth by managing high-volume sales interactions, building lasting client relationships, and exceeding performance metrics. Own your results in a fast-paced environment while leveraging...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Transportation

$70K - $100K *

Champion new business growth by identifying and converting prospects into clients. Own the full sales cycle, leveraging data insights and consultative selling to drive urgency and deliver tailored sol...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Staffing

$95K - $115K *

Join a team that's redefining product marketing by driving impactful go-to-market strategies, enabling sales teams, and translating complex product features into clear customer value across diverse ma...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$272K - $340K *

Join a team that's driving CMC strategy and execution for innovative therapies. Lead cross-functional efforts in drug and device development, ensuring compliance and operational excellence from clinic...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Unlock potential by driving sales for innovative water technology solutions. Engage with utility decision-makers and engineering consultants to enhance product visibility and secure project opportunit...

2 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Champion the development of AI-driven products, leading strategic initiatives and execution. Drive product roadmaps, manage budgets, and ensure alignment with business goals while delivering impactful...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $110K *

Drive full-cycle sales across your territory, self-sourcing leads and closing multi-stakeholder B2B software deals. Collaborate with Solutions Engineers to deliver tailored demos, consistently exceedi...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Information Technology

$160K - $200K *

Advance your career by driving new business growth across North America. Build strategic relationships with senior leaders in AI and technology, leading complex enterprise sales cycles and delivering...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $130K *

Champion strategic partnerships and drive revenue growth through effective channel management and collaborative business planning, ensuring sales success and partner satisfaction while navigating comp...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$150K - $180K *

Transform the Federal landscape by leading enterprise sales efforts, engaging with SES leaders, and driving digital transformation across major accounts. Collaborate with cross-functional teams to ach...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Information Technology

$125K - $150K *

Champion the development of a go-to-market strategy for South Asia, focusing on client acquisition and market expansion. Engage with diverse stakeholders to drive growth and innovation in media produc...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Media

$84K - $109K *

Shape the future of advertising by managing a portfolio of mid-market CPG brands, driving strategic partnerships, and delivering data-driven insights to enhance client growth and revenue on a leading...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Consumer Technology

$112K - $245K *

Lead the charge in transforming Sales Operations through innovative strategies, automation, and AI. Collaborate with clients to enhance efficiency, drive revenue, and redefine operational models for a...

1 week ago

  •   8 - 10 years exp.  •   Business Services

$160K - $200K *

Transform the future of go-to-market strategy by leading cross-functional teams, driving execution governance, and shaping long-range plans to achieve growth objectives in a dynamic, global environmen...

United StatesRemote

1 month ago

  •   11 - 15 years exp.  •   Food & Beverages

$115K - $145K *

Engage in the development and delivery of innovative training programs that enhance the skills and performance of sales teams in the pharma/biotech sector, ensuring alignment with strategic goals and...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$160K - $190K *

Drive impactful multi-channel field marketing strategies that enhance demand generation, strengthen customer relationships, and optimize pipeline performance. Lead a high-performing team while collabo...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Information Technology

$90K - $110K *

Grow your career with a dynamic team focused on generating new business in the public sector. Utilize a consultative sales approach to build relationships and deliver tailored solutions, driving reven...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$105K - $130K *

Join a dynamic team to lead multiple client engagements, driving innovative solutions and strategic direction. Foster cross-functional collaboration in a fast-paced environment with a focus on deliver...

RemoteRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Join us to drive growth in enterprise accounts, owning the full sales cycle from prospecting to closing. Collaborate with a dynamic team to convert leads into revenue while leveraging market insights...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$90K - $110K *

Develop and implement strategic business initiatives to drive growth, expand market presence, and foster partnerships. Lead cross-functional teams to achieve long-term objectives while identifying new...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$125K - $150K *

Join us in empowering enterprise organizations by driving sales of our innovative software platform. Leverage your consultative sales skills to build lasting relationships and help clients enhance the...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Partner with us to drive transformative healthcare solutions by managing key accounts, fostering relationships, and ensuring measurable outcomes. Your expertise will enhance provider partnerships and...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$86K - $138K *

Lead the charge in defining and executing a comprehensive product strategy, driving value across product portfolios. Collaborate with key stakeholders to align strategic vision while overseeing perfor...

RemoteRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Healthcare

$106K - $133K *

Unlock potential by enhancing operational efficiency in the Services organization. You will oversee critical processes, collaborate with cross-functional teams, and ensure a seamless experience for cu...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$75K - $125K *

Unlock potential by driving technology sales in the SLED market. Build relationships, develop new business, and collaborate with experts to deliver tailored solutions while achieving your sales goals...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.