Explore $100K+ Jobs in North Carolina

Discover professional opportunities across North Carolina with Ladders, a job site focused on roles paying $100,000 or more. From established business centers to growing regional markets, the state offers opportunities for experienced professionals seeking their next career move.

North Carolina’s Professional Job Markets

Charlotte is a major hub for banking, financial services, and corporate leadership. The Research Triangle—including Raleigh, Durham, and Chapel Hill—has opportunities across technology, life sciences, healthcare, education, and research. Other cities and regions also support careers in manufacturing, logistics, energy, and professional services.

Roles for Experienced Professionals

Browse senior and specialized openings in areas such as software and technology, finance, healthcare, engineering, sales, operations, and executive leadership. Listings vary by employer and location, so review each posting for its responsibilities, qualifications, work arrangement, and compensation details.

Find Your Next North Carolina Opportunity

Use Ladders to explore vetted professional jobs with salaries of $100,000 or more. Search by job title, employer, or location, and compare openings across North Carolina to find roles that align with your experience and career goals.

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$106K - $147K *

Champion the development of ML pipelines, ensuring scalable, reliable decision-making systems that optimize member outcomes while collaborating with cross-functional teams to enhance platform performa...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Transform the sales landscape by leading a dynamic team of Inside Sales Reps. Drive performance through coaching, pipeline management, and collaboration with cross-functional teams to achieve exceptio...

5 days ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Collaborate to transform events and marketing programs into impactful executive engagement and demand generation. Drive planning, execution, and analysis to enhance partner campaigns and optimize sell...

US-AnywhereRemote

Today

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$130K - $154K *

Collaborate with cross-functional teams to enhance customer onboarding experiences through strategic program management, leveraging data-driven insights and operational excellence to drive product imp...

US-AnywhereRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$95K - $110K *

Drive profitable growth by providing innovative aftermarket solutions for key accounts, focusing on system retrofits and upgrades. Collaborate with teams and leverage your expertise to meet customer n...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$160K - $200K *

Transform organizational effectiveness by partnering with leadership to drive talent strategy, succession planning, and performance management across the Hospitality Vertical, ensuring alignment with...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$82K - $137K *

Transform vaccine manufacturing processes by leading optimization studies and tech transfers. Collaborate with teams to troubleshoot and enhance production efficiency while ensuring safety and complia...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Champion your career by conducting in-depth research and analysis to produce impactful industry insights for top executives in home services, driving strategic decisions and fostering key relationship...

Today

  •   Less than 5 years exp.  •   Enterprise Technology

$230K - $260K *

Lead the charge in executing an investor relations strategy, enhancing financial communications and engagement with stakeholders to foster a compelling investment narrative and support long-term value...

US-AnywhereRemote

4 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$129K - $177K *

Help us optimize third-party cybersecurity risk management strategies, ensuring robust protection against diverse threats. Lead initiatives, collaborate with stakeholders, and drive risk-based decisio...

US-AnywhereRemote

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$87K - $157K *

Unlock compliance excellence by managing auditing, monitoring, and reporting processes to ensure adherence to regulatory standards and enhance operational efficiency across contracts and collaboration...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$220K - $274K *

Join a team that's shaping compliance strategies and operations for U.S. sanctions and AML regulations. Collaborate with cross-functional teams while driving sustainable growth through effective risk...

3 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$153K - $230K *

Engage with healthcare professionals in a dynamic role focused on promoting a cutting-edge PET imaging agent. Drive demand, develop strategic partnerships, and ultimately enhance patient care through...

US-AnywhereRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Business Services

$150K - $180K *

Accelerate progress at large enterprise accounts by driving sales, expanding customer relationships, and establishing strategic partnerships in cybersecurity and AI within the Pacific Northwest. Ignit...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$100K - $120K *

Drive the accounting excellence within a dynamic team, overseeing journal entries, reconciliations, and financial reporting to ensure timely and accurate month-end closes while collaborating cross-fun...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Energy & Utilities

$83K - $140K *

Lead the charge in financial modeling and forecasting, driving strategic insights and collaborative planning processes across Corporate Finance & Strategy to optimize performance and align financial g...

US-AnywhereRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$100K - $231K *

Lead the charge in creating innovative omnichannel experiences that blend customer engagement with strong brand presence across physical and digital environments, driving effective design strategies a...

US-AnywhereRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$145K - $175K *

Champion the design and implementation of scalable AI architectures, integrating data, models, and governance. Collaborate with cross-functional teams to drive enterprise AI solutions from concept to...

Today

  •   8 - 10 years exp.  •   Information Technology

$78K - $150K *

Transform security operations by ensuring after-hours monitoring, reviewing critical events, and documenting procedures. Collaborate across teams to enhance account safety and improve processes in the...

2 weeks ago

  •   Less than 5 years exp.  •   Transportation

$150K - $250K *

Drive business growth by leveraging strategic client relationships and mastering sales strategies. This role fosters collaboration across teams to meet customer needs while achieving revenue goals, en...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Technical Services

$77K - $202K *

Empower clients by analyzing procurement strategies, enhancing cost performance, and fostering supplier collaboration. As a Senior Associate, you'll lead workstreams, mentor junior team members, and d...

1 week ago

  •   Less than 5 years exp.  •   Legal & Accounting

$77K - $202K *

Drive procurement strategy and value capture initiatives, enhancing client cost performance and supplier collaboration. Manage workstreams, analyze data, and guide junior team members to improve opera...

1 week ago

  •   Less than 5 years exp.  •   Legal & Accounting

$77K - $155K *

Drive full-cycle sales from prospecting to contract negotiation, ensuring customer satisfaction. Collaborate with a high-performing team and leverage innovative tools to exceed sales goals and deliver...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$230K - $322K *

Optimize machine learning infrastructure and tooling to enhance efficiency, reduce costs, and improve performance. Collaborate with cross-functional teams to drive productivity and scalability in ML s...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Media

$114K - $135K *

Transform event experiences by leading strategy and execution for high-impact trade shows and corporate events. Collaborate cross-functionally to drive brand awareness and measurable business impact i...

US-AnywhereRemote

6 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    Listings may include senior and specialized roles in technology, finance, healthcare, engineering, sales, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Which North Carolina cities have professional job opportunities?question toggle

    Opportunities can be found in Charlotte, Raleigh, Durham, Chapel Hill, and other North Carolina cities and regions. Search by location to see current openings.

  • Does Ladders list jobs paying $100,000 or more?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Check individual postings for compensation information and role details.

  • How can I search for jobs in North Carolina?question toggle

    Search Ladders by job title, employer, or North Carolina location, then review listings for qualifications, responsibilities, work arrangement, and compensation.