Explore $100K+ Jobs in North Carolina

Discover professional opportunities across North Carolina with Ladders, a job site focused on roles paying $100,000 or more. From established business centers to growing regional markets, the state offers opportunities for experienced professionals seeking their next career move.

North Carolina’s Professional Job Markets

Charlotte is a major hub for banking, financial services, and corporate leadership. The Research Triangle—including Raleigh, Durham, and Chapel Hill—has opportunities across technology, life sciences, healthcare, education, and research. Other cities and regions also support careers in manufacturing, logistics, energy, and professional services.

Roles for Experienced Professionals

Browse senior and specialized openings in areas such as software and technology, finance, healthcare, engineering, sales, operations, and executive leadership. Listings vary by employer and location, so review each posting for its responsibilities, qualifications, work arrangement, and compensation details.

Find Your Next North Carolina Opportunity

Use Ladders to explore vetted professional jobs with salaries of $100,000 or more. Search by job title, employer, or location, and compare openings across North Carolina to find roles that align with your experience and career goals.

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$108K - $162K *

Inspire growth by driving strategic client relationships and delivering exceptional insights. Leverage your consultative sales expertise to partner with C-level executives in Fortune-class companies a...

1 week ago

  •   8 - 10 years exp.  •   Business Services

$70K - $90K *

Optimize Field Marketing operations by managing workflows, systems, and data integrity to ensure seamless execution of events and initiatives, while supporting cross-functional teams in achieving mark...

US-AnywhereRemote

4 weeks ago

  •   Less than 5 years exp.  •   Legal & Accounting

$79K - $118K *

Shape your nursing career by providing exceptional care in a renowned Neurosciences Unit. Collaborate with a dynamic team dedicated to improving patient outcomes and fostering a culture of excellence...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $135K *

Empower clinical research excellence by managing projects that ensure compliance with regulatory requirements and drive successful study delivery from initiation to closeout. Collaborate with interdis...

US-AnywhereRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$60K - $120K *

Engage in the dynamic creator economy as a Senior Talent Manager. Drive talent representation, negotiate impactful brand partnerships, and lead the evolution of creator management while fostering a cu...

US-AnywhereRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Media

$69K - $97K *

Engage with prospects as an Inside Sales Account Manager, driving revenue growth by generating leads, closing sales, and ensuring customer satisfaction through exceptional service and collaboration wi...

US-AnywhereRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$140K *

Lead the charge in driving growth strategies for large omnichannel merchants, while optimizing partnerships and implementing actionable plans. Collaborate with stakeholders to deliver measurable ROI a...

US-AnywhereRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$71K - $107K *

Shape customer relationships and drive sales growth in a dynamic territory. Utilize consultative techniques to enhance value and identify new business opportunities while managing a healthy pipeline o...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $100K *

Innovate within the retirement solutions sector by driving sales of qualified plans to small and mid-sized markets. Build relationships with financial intermediaries and manage a dynamic territory to...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$71K - $107K *

Grow sales and build strong client relationships in a dynamic market. Utilize consultative techniques to drive revenue, enhance solutions, and identify new business opportunities. Collaborate with tea...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$82K - $123K *

Contribute to employee engagement and lifecycle services by partnering with teams, executing onboarding processes, and facilitating cultural initiatives for a positive workplace experience in a large...

2 weeks ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$82K - $123K *

Empower progress by delivering key employee lifecycle services, supporting onboarding and engagement initiatives, and ensuring consistent application of People Practices, all while fostering a positiv...

2 weeks ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$110K - $130K *

Lead the charge in driving strategic project initiatives across diverse departments, ensuring timely execution from inception to delivery. Foster collaboration and accountability in a fast-paced, high...

US-AnywhereRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$142K - $211K *

Lead financial analysis and reporting for the business unit, ensuring accuracy and alignment with strategic goals. Collaborate with senior management to provide insights that drive informed decision-m...

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$175K - $220K *

Drive business development in the waste and recycling sector, identifying and closing strategic opportunities. Leverage industry expertise to build partnerships and enhance commercial growth while nav...

1 week ago

  •   8 - 10 years exp.  •   Staffing

$94K - $124K *

Lead operational excellence by managing our CLM platform, ensuring efficient contract processes and seamless collaboration among stakeholders, vendors, and technology to optimize procurement operation...

US-AnywhereRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$90K - $122K *

Drive the design and deployment of AI-powered applications, integrating advanced technologies to enhance business processes. Collaborate across teams to deliver scalable solutions while ensuring compl...

1 week ago

  •   Less than 5 years exp.  •   Legal & Accounting

$90K - $122K *

Transform business needs into innovative AI solutions by designing, developing, and deploying AI applications and automation tools. Collaborate across teams to enhance workflows and deliver scalable t...

1 week ago

  •   Less than 5 years exp.  •   Legal & Accounting

$90K - $122K *

Unlock potential by designing and deploying AI solutions that enhance business processes. Collaborate across teams to develop scalable applications, ensuring reliability and compliance while driving i...

1 week ago

  •   Less than 5 years exp.  •   Legal & Accounting

$90K - $122K *

Join a team that's redefining AI solutions by designing, developing, and deploying innovative applications and automation tools. Collaborate across the full development lifecycle to enhance business p...

1 week ago

  •   Less than 5 years exp.  •   Legal & Accounting

$90K - $122K *

Develop AI-powered applications and automation solutions, transforming business needs into scalable technology. Collaborate across teams to design, build, and deploy innovative AI solutions while ensu...

1 week ago

  •   Less than 5 years exp.  •   Legal & Accounting

$116K - $143K *

Champion data integrity by ensuring accuracy and governance, enabling impactful business analytics solutions and driving consistent data quality across the organization through mastery of data process...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$95K - $139K *

Join a team that's dedicated to enhancing employee relations across diverse environments. As a trusted advisor, you'll manage complex issues, conduct investigations, and provide strategic recommendati...

US-AnywhereRemote

Today

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$110K - $130K *

Drive success by enhancing client engagement and product adoption across enterprise accounts. Act as a trusted advisor, ensuring clients fully realize value from their investments while strengthening...

US-AnywhereRemote

4 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$80K - $95K *

Join a dynamic finance team to optimize month-end close processes, enhance internal controls, and support financial reporting. Collaborate across departments to ensure accuracy and scalability as the...

US-AnywhereRemote

5 days ago

  •   Less than 5 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    Listings may include senior and specialized roles in technology, finance, healthcare, engineering, sales, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Which North Carolina cities have professional job opportunities?question toggle

    Opportunities can be found in Charlotte, Raleigh, Durham, Chapel Hill, and other North Carolina cities and regions. Search by location to see current openings.

  • Does Ladders list jobs paying $100,000 or more?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Check individual postings for compensation information and role details.

  • How can I search for jobs in North Carolina?question toggle

    Search Ladders by job title, employer, or North Carolina location, then review listings for qualifications, responsibilities, work arrangement, and compensation.