Explore $100K+ Jobs in North Carolina

Discover professional opportunities across North Carolina with Ladders, a job site focused on roles paying $100,000 or more. From established business centers to growing regional markets, the state offers opportunities for experienced professionals seeking their next career move.

North Carolina’s Professional Job Markets

Charlotte is a major hub for banking, financial services, and corporate leadership. The Research Triangle—including Raleigh, Durham, and Chapel Hill—has opportunities across technology, life sciences, healthcare, education, and research. Other cities and regions also support careers in manufacturing, logistics, energy, and professional services.

Roles for Experienced Professionals

Browse senior and specialized openings in areas such as software and technology, finance, healthcare, engineering, sales, operations, and executive leadership. Listings vary by employer and location, so review each posting for its responsibilities, qualifications, work arrangement, and compensation details.

Find Your Next North Carolina Opportunity

Use Ladders to explore vetted professional jobs with salaries of $100,000 or more. Search by job title, employer, or location, and compare openings across North Carolina to find roles that align with your experience and career goals.

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$200K - $398K *

Join a team that's redefining legal leadership in global clinical research. Leverage your expertise to navigate complex legal matters, support business growth, and mentor legal professionals while col...

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$80K - $95K *

Drive business growth by managing the entire sales cycle with government accounts. Build relationships, exceed sales goals, and treat your territory as your own business to achieve success and revenue...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Lead end-to-end client engagements for complex AI and digital projects, managing multiple implementations while ensuring timely delivery and exceeding client expectations. Collaborate with cross-funct...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$79K - $118K *

Join a dedicated team in our unique Medical Oncology ICU, delivering expert care and support to complex cancer patients. Collaborate with specialists in a high-acuity environment devoted to healing an...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$85K - $100K *

Lead and manage complex data center projects from initiation to completion, ensuring compliance with safety standards, budget adherence, and project timelines while fostering opportunities for profess...

3 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$170K - $205K *

Drive the integration and growth of a newly acquired business, overseeing P&L, client relationships, and operations. Collaborate with teams to ensure seamless transition and performance against revenu...

US-AnywhereRemote

Today

  •   5 - 7 years exp.  •   Real Estate & Construction

$75K - $90K *

Elevate your career by driving B2B demand generation through new client acquisition and account growth. Build strong relationships with key stakeholders while leveraging AI to enhance your sales strat...

US-AnywhereRemote

5 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$79K - $118K *

Champion patient care as a Registered Nurse in a dynamic Emergency Department, focusing on safety, teamwork, and innovative practices to enhance patient experiences and outcomes in a community-centere...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$105K - $115K *

Develop and refine payroll operations for a growing workforce of over 500 employees. Ensure compliant and efficient processing while managing benefit administration and optimizing internal controls an...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$180K - $200K *

Shape the future of technology as a senior technical leader, driving complex initiatives and mentoring engineers. Collaborate with cross-functional teams to deliver scalable, secure cloud-native solut...

US-AnywhereRemote

Today

  •   11 - 15 years exp.  •   Media

$125K - $171K *

Unlock your potential by managing talent processes that enhance performance and drive growth. Collaborate with leaders to implement effective talent strategies, support career development, and leverag...

US-AnywhereRemote

Today

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Support project delivery as an Associate Engagement Manager, collaborating with teams on Workday implementations and ensuring customer satisfaction while driving innovation and strategic growth in the...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$95K - $115K *

Transform legal operations by managing contracts, enhancing workflows, and streamlining processes. Collaborate cross-functionally to support compliance, project tracking, and implement tools for effic...

2 weeks ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$85K - $115K *

Join a dynamic team to drive sales of mission-critical technology for public safety. Engage with emergency response agencies, navigate complex procurement cycles, and deliver innovative solutions that...

US-AnywhereRemote

6 days ago

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$80K - $115K *

Drive impactful storytelling and enhance brand reputation through strategic PR initiatives, collaboration with marketing teams, and management of agency partnerships. Elevate your communications skill...

US-AnywhereRemote

5 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$89K - $148K *

Innovate integrated solutions for complex power systems, leading design and architecture efforts while collaborating with cross-functional teams to enhance performance and reliability in energy applic...

6 days ago

  •   5 - 7 years exp.  •   Business Services

$89K - $148K *

Shape the future of integrated power systems by leading innovative solutions and ensuring seamless integration of complex technologies. Collaborate with cross-functional teams to deliver exceptional o...

US-AnywhereRemote

6 days ago

  •   5 - 7 years exp.  •   Business Services

$100K - $125K *

Join the team to drive business performance through strategic people initiatives. Collaborate with leaders to enhance organizational effectiveness, talent development, and employee engagement while en...

5 days ago

  •   5 - 7 years exp.  •   Transportation

$110K - $130K *

Champion product innovation by driving end-to-end development, collaborating closely with engineering and customers. Leverage AI tools and customer insights to shape product strategy and deliver impac...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$130K - $150K *

Champion strategic direction and team excellence in social media buying. Drive business growth, oversee media execution, and mentor high-performing teams while maintaining deep industry expertise and...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Media

$132K - $170K *

Unlock client growth opportunities through strategic relationships, driving value in a fast-paced B2B sales environment. Collaborate with C-Level Executives across diverse sectors to ensure client sat...

US-AnywhereRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Business Services

$101K - $140K *

Join a dynamic team to drive client growth and retention by building trust-based relationships with C-Level Executives, ensuring they maximize value from services while identifying new opportunities f...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$150K - $190K *

Accelerate customer growth by managing relationships with key accounts and driving revenue expansion. Become an expert on our products to ensure customer success, guiding them through technical use an...

US-AnywhereRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Shape the future of procurement by leading strategic sourcing initiatives, enhancing vendor relationships, and driving financial transparency. Collaborate across teams to streamline processes and leve...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$68K - $103K *

Join our team to perform CT procedures with expertise, operating advanced equipment while ensuring patient safety and comfort. Collaborate with medical staff to provide exceptional care while enhancin...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    Listings may include senior and specialized roles in technology, finance, healthcare, engineering, sales, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Which North Carolina cities have professional job opportunities?question toggle

    Opportunities can be found in Charlotte, Raleigh, Durham, Chapel Hill, and other North Carolina cities and regions. Search by location to see current openings.

  • Does Ladders list jobs paying $100,000 or more?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Check individual postings for compensation information and role details.

  • How can I search for jobs in North Carolina?question toggle

    Search Ladders by job title, employer, or North Carolina location, then review listings for qualifications, responsibilities, work arrangement, and compensation.