Explore $100K+ Jobs in North Carolina

Discover professional opportunities across North Carolina with Ladders, a job site focused on roles paying $100,000 or more. From established business centers to growing regional markets, the state offers opportunities for experienced professionals seeking their next career move.

North Carolina’s Professional Job Markets

Charlotte is a major hub for banking, financial services, and corporate leadership. The Research Triangle—including Raleigh, Durham, and Chapel Hill—has opportunities across technology, life sciences, healthcare, education, and research. Other cities and regions also support careers in manufacturing, logistics, energy, and professional services.

Roles for Experienced Professionals

Browse senior and specialized openings in areas such as software and technology, finance, healthcare, engineering, sales, operations, and executive leadership. Listings vary by employer and location, so review each posting for its responsibilities, qualifications, work arrangement, and compensation details.

Find Your Next North Carolina Opportunity

Use Ladders to explore vetted professional jobs with salaries of $100,000 or more. Search by job title, employer, or location, and compare openings across North Carolina to find roles that align with your experience and career goals.

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$79K - $118K *

Transform patient care as a dedicated RN, coordinating comprehensive care while delivering safe, therapeutic support. Join a team committed to excellence within a dynamic medical-surgical environment...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$140K - $160K *

Engage clients by analyzing requirements, delivering tailored Salesforce solutions, and leading end-to-end implementations across multiple clouds. Collaborate with cross-functional teams to optimize p...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$100K - $140K *

Join a team that's driving innovation by delivering tailored Salesforce solutions, optimizing client business processes, and enhancing operational efficiency through expert configuration, testing, and...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Business Services

$184K - $205K *

Discover financial modeling as you drive sales compensation and capacity strategies. Own accurate forecasts, empower executive decision-making, and transform complex data into actionable insights. Col...

US-AnywhereRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $100K *

Transform your career with this client-facing role, leveraging your expertise in analytics tools like Google Analytics and Tag Manager to deliver strategic solutions and enhance data-driven decision-m...

US-AnywhereRemote

Reposted today

  •   Less than 5 years exp.  •   Media

$132K - $220K *

Lead the charge in managing Renewable Energy Hydro Projects, driving execution strategies to maximize performance, ensuring timely delivery, and fostering strong customer relationships while overseein...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$113K - $188K *

Unlock potential by delivering comprehensive Workday solutions, optimizing clients' environments through assessments and tailored implementations, while leading design and development efforts to enhan...

US-AnywhereRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Business Services

$100K - $120K *

Deliver impactful sales growth by driving SaaS solutions in hospital pharmacy markets. Collaborate with various teams, engage with senior executives, and achieve targets through strategic selling and...

US-AnywhereRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$73K - $110K *

Join a dynamic healthcare team to provide exceptional nursing care, engage in quality initiatives, and collaborate with multidisciplinary teams to enhance patient outcomes while promoting a culture of...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$73K - $110K *

Join a team that's dedicated to providing exceptional pediatric care through evidence-based practices and compassionate support. Collaborate with medical professionals to enhance patient outcomes in a...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$73K - $110K *

Grow your career with a role that enhances patient care through evidence-based practices, engages in team collaboration, and promotes safety in a dynamic setting, all while upholding nursing excellenc...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$73K - $110K *

Transform patient care by providing exceptional nursing services and collaborating with healthcare teams to enhance outcomes and elevate care standards. Engage in continuous improvement and uphold a c...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$74K - $110K *

Join a team that's dedicated to providing exceptional patient care while leveraging evidence-based practices. Engage with a collaborative care team to influence patient outcomes and promote a culture...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$73K - $110K *

Contribute to exceptional patient care by utilizing evidence-based nursing practices, managing clinical operations, and collaborating with health teams to foster a safe, dynamic environment. Engage in...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$73K - $110K *

Join a dedicated team in providing compassionate nursing care through assessment, planning, implementation, and evaluation, while driving quality initiatives and enhancing patient safety within a coll...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$77K - $109K *

Support the NRI external sales team by identifying and nurturing opportunities to sell retirement products, while maintaining CRM data and collaborating on sales strategies to drive asset growth in a...

3 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$82K - $132K *

Lead the charge in driving sales growth and account management for small-to-medium sized accounts. Utilize a blend of field and inside sales techniques to maximize profitability and develop strategic...

Today

  •   Less than 5 years exp.  •   Enterprise Technology

$79K - $118K *

Advance healthcare delivery by facilitating patient-centered care coordination, actively engaging multidisciplinary teams, and overcoming barriers to ensure optimal outcomes throughout the patient's j...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Champion the employee experience as a strategic HR leader, driving operational excellence and fostering a welcoming culture. Manage talent acquisition and employee relations while implementing innovat...

2 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$73K - $110K *

Elevate child advocacy through compassionate nursing care, conducting forensic interviews, and collaborating in multidisciplinary teams to provide safe, therapeutic support for abused and neglected ch...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$71K - $97K *

Unlock your potential in a high-visibility role enhancing workforce planning and budgeting processes within a dynamic clinical pharmacy environment, collaborating cross-functionally to drive operation...

US-AnywhereRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Unlock potential by driving strategic growth within enterprise accounts. Lead cross-functional teams to manage client relationships, develop account strategies, and identify new opportunities, ensurin...

US-AnywhereRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$143K - $179K *

Shape and lead client implementations for a cutting-edge trading platform, guiding asset and wealth managers through system configuration and go-live processes while ensuring client satisfaction and p...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$90K - $110K *

Lead the charge in managing and expanding a strategic book of business in large fleet fuel sales while identifying and capitalizing on growth opportunities for new and existing clients in the transpor...

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Transportation

$100K - $120K *

Join a team that's driving the evolution of our Deal Desk function, balancing hands-on deal execution with strategic guidance to support high-quality deals. You'll enhance collaboration across teams...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    Listings may include senior and specialized roles in technology, finance, healthcare, engineering, sales, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Which North Carolina cities have professional job opportunities?question toggle

    Opportunities can be found in Charlotte, Raleigh, Durham, Chapel Hill, and other North Carolina cities and regions. Search by location to see current openings.

  • Does Ladders list jobs paying $100,000 or more?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Check individual postings for compensation information and role details.

  • How can I search for jobs in North Carolina?question toggle

    Search Ladders by job title, employer, or North Carolina location, then review listings for qualifications, responsibilities, work arrangement, and compensation.