Explore $100K+ Jobs in North Carolina

Discover professional opportunities across North Carolina with Ladders, a job site focused on roles paying $100,000 or more. From established business centers to growing regional markets, the state offers opportunities for experienced professionals seeking their next career move.

North Carolina’s Professional Job Markets

Charlotte is a major hub for banking, financial services, and corporate leadership. The Research Triangle—including Raleigh, Durham, and Chapel Hill—has opportunities across technology, life sciences, healthcare, education, and research. Other cities and regions also support careers in manufacturing, logistics, energy, and professional services.

Roles for Experienced Professionals

Browse senior and specialized openings in areas such as software and technology, finance, healthcare, engineering, sales, operations, and executive leadership. Listings vary by employer and location, so review each posting for its responsibilities, qualifications, work arrangement, and compensation details.

Find Your Next North Carolina Opportunity

Use Ladders to explore vetted professional jobs with salaries of $100,000 or more. Search by job title, employer, or location, and compare openings across North Carolina to find roles that align with your experience and career goals.

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$100K - $192K *

Shape the future of healthcare by developing key relationships with health system accounts. Utilize your sales acumen to navigate complex organizational structures, identify opportunities, and deliver...

US-AnywhereRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Shape your career by leading plant marketing initiatives, driving new business, and collaborating with management to achieve strategic goals while fostering a high-performance team culture...

Yesterday

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$86K - $91K *

Lead the People Operations function, driving employee relations, compliance, and engagement initiatives across the U.S. and Canada. Collaborate with leadership to enhance policies and processes while...

US-AnywhereRemote

3 days ago

  •   5 - 7 years exp.  •   Transportation

$170K - $200K *

Lead impactful internal communications strategies, partnering with executives to shape narratives in an AI-native environment. Define best practices and ensure effective messaging for a globally distr...

US-AnywhereRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$80K - $95K *

Lead the execution of a major retrieval program by managing provider relationships, training staff, and enhancing operational workflows. Drive team performance and resolve escalations effectively in a...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$171K - $231K *

Drive innovative patient recruitment strategies to enhance clinical trial enrollment and retention. Collaborate with cross-functional teams to implement data-driven approaches, optimize patient engage...

US-AnywhereRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Engage in high-quality legal research to support law firm clients, focusing on intellectual property matters. Utilize advanced research tools to deliver accurate results and synthesize findings into a...

US-AnywhereRemote

6 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$111K - $213K *

Join a team that's dedicated to optimizing engineering processes, enhancing system performance, and solving complex challenges in instrumentation and control. Utilize your expertise to drive impactful...

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$125K - $150K *

Join a team that's redefining information governance by leading records retention and eDiscovery initiatives. Drive compliance, oversee technology, and ensure defensible data management across the org...

4 days ago

  •   8 - 10 years exp.  •   Legal & Accounting

$74K - $128K *

Join a team that's dedicated to enhancing employee relations in a dynamic manufacturing environment. As a key advisor, you'll foster positive workplace experiences, resolve conflicts, and support effe...

5 days ago

  •   5 - 7 years exp.  •   Business Services

$79K - $119K *

Join a dynamic team to shape investor communications and insights, supporting senior leadership and enhancing engagement with analysts and institutional investors through compelling financial messagin...

3 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$105K - $115K *

Engage as the primary client representative overseeing multiple fitness center locations, guiding revenue goals, analyzing trends, and ensuring operational excellence while collaborating with corporat...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$250K - $280K *

Shape the future of our enterprise sales segment by driving growth and account success. Take ownership of new logo acquisitions, deepen existing client relationships, and establish best practices for...

US-AnywhereRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $300K *

Transform enterprise sales by driving innovative messaging solutions and closing six-figure deals. Leverage your expertise to engage top brands, manage the sales cycle, and foster strong relationships...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Media

$108K - $181K *

Engineer innovative commercial strategies that drive growth and enhance contract management for a fast-evolving portfolio in the controls services domain. Collaborate with cross-functional teams to op...

US-AnywhereRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Business Services

$115K - $125K *

Transform workforce strategy by partnering with leaders to align talent and capabilities with business goals. Drive organizational design, manage performance, and build frameworks that empower decisio...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $110K *

Lead impactful copywriting initiatives, collaborating with teams to develop compelling messages for healthcare brands. Mentor peers and drive project success, ensuring quality and accuracy while stayi...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $135K *

Transform the sales landscape by driving enterprise growth and building robust client relationships. Engage with key decision-makers to showcase Microsoft solutions and exceed sales targets through st...

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$200K - $300K *

Empower your career by driving growth through strategic sales efforts. You'll shape client relationships and manage a robust pipeline while collaborating across teams to deliver exceptional solutions...

US-AnywhereRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$100K - $120K *

Transform the employee experience by leading impactful HR initiatives, managing events, and enhancing organizational culture. Collaborate across teams to drive engagement, support leadership developme...

US-AnywhereRemote

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $110K *

Join us to streamline talent operations and enhance quality management for mentors and instructors across multiple programs. This impactful role fosters collaboration, builds scalable processes, and d...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$85K - $110K *

Drive your career with a Senior Accountant role focused on AI and automation. Redesign accounting processes, manage monthly closes, and implement scalable finance workflows to enhance efficiency and s...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Consumer Technology

$80K - $95K *

Transform engineering solutions in Battery Cell production by leading cross-functional teams to drive effective problem-solving, enhance processes, and support organizational growth through innovative...

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$90K - $110K *

Unlock new business opportunities by engaging prospective clients through phone and web interactions. Collaborate cross-functionally to drive sales growth for a dynamic company in the fast-growing gov...

US-AnywhereRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$70K - $100K *

Join a team that's dedicated to enhancing lives through quality Occupational Therapy. Collaborate in a clinic setting, delivering essential care for children and adults while working alongside diverse...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    Listings may include senior and specialized roles in technology, finance, healthcare, engineering, sales, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Which North Carolina cities have professional job opportunities?question toggle

    Opportunities can be found in Charlotte, Raleigh, Durham, Chapel Hill, and other North Carolina cities and regions. Search by location to see current openings.

  • Does Ladders list jobs paying $100,000 or more?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Check individual postings for compensation information and role details.

  • How can I search for jobs in North Carolina?question toggle

    Search Ladders by job title, employer, or North Carolina location, then review listings for qualifications, responsibilities, work arrangement, and compensation.