Explore $100K+ Jobs in California

Discover professional opportunities across California with Ladders. From established business centers to growing regional economies, the state offers senior-level roles in technology, healthcare, finance, entertainment, manufacturing, and more. Browse vetted job listings with salaries of $100,000 or higher and find positions that align with your experience and career goals.

California industries and career opportunities

California’s diverse economy supports leadership and specialized roles at companies of all sizes. Depending on your background, you may find opportunities in software and technology, life sciences, healthcare, financial services, clean energy, media, aerospace, and professional services. Job availability and compensation vary by role, employer, and location.

Find jobs throughout the state

Explore openings in major employment centers such as Los Angeles, San Francisco, San Diego, San Jose, Sacramento, and surrounding communities. Listings may include on-site, hybrid, and remote arrangements; review each posting for its work location and requirements.

Search with Ladders

Use Ladders to focus your search on vetted professional jobs paying $100,000 or more. Review role responsibilities, qualifications, compensation details, and workplace expectations, then apply directly to opportunities that fit your goals. Keep your profile and resume current so employers can better understand your experience.

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1,000+

Jobs in California

Average Salary in USD

Average Salary: $142,597

Sort By: Relevance

$95K - $115K *

Lead the management support for Acquisition Planning, Programming, Budgeting, and Execution (PPBE) processes related to IT programs, ensuring effective oversight and implementation of financial requir...

Yesterday

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$145K - $185K *

Transform account-based marketing strategies into impactful campaigns that drive pipeline growth and revenue. Lead integrated initiatives across multiple channels, ensuring alignment with sales and ma...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Information Technology

$80K - $105K *

Accelerate progress at enhancing production efficiency and quality by analyzing processes, implementing improvements, and collaborating across teams in manufacturing and engineering environments to dr...

Reposted yesterday

  •   Less than 5 years exp.  •   Healthcare

$130K - $155K *

Join a team that's dedicated to ensuring reliability at scale. You'll manage compute, networking, and storage, driving performance and stability while adapting to rapid changes in production environme...

San Francisco, CARemote

Yesterday

  •   Less than 5 years exp.  •   Information Technology

$168K - $228K *

Transform global GxP Change Management processes by leading strategy, governance, and continuous improvement initiatives across the product lifecycle, ensuring effective risk-based changes and collabo...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$138K - $188K *

Lead global trade compliance initiatives, ensuring adherence to regulations across multiple jurisdictions. Drive strategic programs for import/export operations, risk management, and partner governanc...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$73K - $109K *

Empower our storeroom operations by leading a team focused on inventory management, ensuring material availability, and driving continuous improvement across maintenance and repair functions to suppor...

Yesterday

  •   5 - 7 years exp.  •   Food & Beverages

$85K - $110K *

Join us to provide expert technical support for Windows and Mac systems, ensuring seamless operation of desktop and mobile devices. Collaborate with teams to resolve issues and enhance user experience...

Yesterday

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$67K - $204K *

Lead the charge in recruiting top talent for special projects, driving strategic initiatives and enhancing team capabilities. Collaborate across departments to identify needs and implement effective h...

Yesterday

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$85K - $100K *

Join us to lead nursing care for patients with complex Nephrology needs. Utilize your expertise to enhance patient outcomes, oversee clinical teams, and implement high reliability principles in a coll...

Yesterday

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$210K - $250K *

Transform the landscape of affordable housing by advising on investment strategies and programs. Collaborate with senior leadership to define vision and drive company performance while navigating chal...

Yesterday

  •   15+ years exp.  •   Real Estate & Construction

$122K - $150K *

Optimize robotic systems by developing algorithms and software for simulation in aerospace and planetary exploration, collaborating with a multi-disciplinary team to meet project needs and enhance cap...

Yesterday

  •   Less than 5 years exp.  •   Aerospace & Defense

$110K - $150K *

Elevate your career as you design and implement cloud-based integrations for financial systems, enhancing efficiency and automation across Capital Markets, Treasury, and Accounting functions while col...

Reposted yesterday

  •   5 - 7 years exp.  •   Real Estate & Construction

$133K - $275K *

Transform the digital landscape of legal research by leading innovative technology initiatives and enhancing scholarly communication at a premier academic law library. Drive strategic advancements in...

Yesterday

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Engineer critical electrical and mechanical systems for data centers, leading field support, troubleshooting, and reliability improvements while developing operational standards and mentoring teams to...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Information Technology

$160K *

Join a dynamic team to drive adoption of innovative medical solutions, enhancing patient care through strategic partnerships and market growth initiatives in high-acuity environments...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$141K - $211K *

Accelerate progress at the forefront of AI infrastructure by leading mechanical design for advanced rack systems. Shape innovative solutions through hands-on engineering, collaboration, and mentorship...

Yesterday

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Lead the charge in enhancing health, safety, and environmental performance across data center construction projects. Collaborate with teams to ensure compliance with OSHA standards and drive continuou...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$150K - $180K *

Lead the charge in developing cutting-edge lab environments, managing infrastructure projects, and collaborating with cross-functional teams to ensure timely delivery of product roadmaps while navigat...

Yesterday

  •   Less than 5 years exp.  •   Information Technology

$150K - $180K *

Join a dynamic team to shape and launch innovative solutions, driving customer adoption and measurable impact. Collaborate across functions to navigate ambiguity and build scalable processes that empo...

Reposted yesterday

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Support critical HR processes by coordinating performance reviews, promotions, and employee relations. Collaborate with teams to maintain accurate data and enhance the employee experience while managi...

Yesterday

  •   Less than 5 years exp.  •   Business Services

$110K - $130K *

Innovate in cancer research by designing and deploying advanced AI and machine learning solutions. Collaborate with cross-functional teams to develop multimodal models integrating diverse clinical dat...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$108K - $130K *

Transform operations by tackling complex challenges end-to-end, partnering with leaders to enhance systems and drive efficiency. Engage in diverse tasks from contract negotiations to team building, en...

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$93K - $105K *

Provide essential nursing services and support for individuals with developmental disabilities and complex medical needs. Collaborate with healthcare professionals to implement care plans in a support...

Reposted yesterday

  •   Less than 5 years exp.  •   Healthcare

$167K - $204K *

Drive operational excellence by managing value streams, ensuring safety, quality, and cost-effectiveness. Collaborate cross-functionally to enhance performance and lead continuous improvement initiati...

Yesterday

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in California?question toggle

    California listings may include senior and specialized roles in technology, healthcare, finance, life sciences, entertainment, clean energy, manufacturing, and other fields. Available positions depend on current employer needs.

  • Where in California can I search for jobs?question toggle

    You can explore opportunities across the state, including major employment hubs such as Los Angeles, San Francisco, San Diego, San Jose, and Sacramento. Check each posting for its specific location and work arrangement.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for compensation information and details, since pay can vary by position and employer.

  • Can I find remote or hybrid California jobs?question toggle

    Some listings may offer remote or hybrid work, while others require on-site work. The job posting provides the employer’s location and work arrangement requirements.

  • How can I improve my California job search?question toggle

    Narrow your search by role, location, industry, and work arrangement. Keep your resume and profile updated, and carefully compare each opportunity’s qualifications and compensation details.