Explore $100K+ Jobs in California

Discover professional opportunities across California with Ladders. From established business centers to growing regional economies, the state offers senior-level roles in technology, healthcare, finance, entertainment, manufacturing, and more. Browse vetted job listings with salaries of $100,000 or higher and find positions that align with your experience and career goals.

California industries and career opportunities

California’s diverse economy supports leadership and specialized roles at companies of all sizes. Depending on your background, you may find opportunities in software and technology, life sciences, healthcare, financial services, clean energy, media, aerospace, and professional services. Job availability and compensation vary by role, employer, and location.

Find jobs throughout the state

Explore openings in major employment centers such as Los Angeles, San Francisco, San Diego, San Jose, Sacramento, and surrounding communities. Listings may include on-site, hybrid, and remote arrangements; review each posting for its work location and requirements.

Search with Ladders

Use Ladders to focus your search on vetted professional jobs paying $100,000 or more. Review role responsibilities, qualifications, compensation details, and workplace expectations, then apply directly to opportunities that fit your goals. Keep your profile and resume current so employers can better understand your experience.

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1,000+

Jobs in California

Average Salary in USD

Average Salary: $142,597

Sort By: Relevance

$95K - $181K *

Join a team that's dedicated to ensuring the seamless operation of classified network infrastructure. Leverage your expertise in network engineering to support critical defense programs and enhance co...

Yesterday

  •   Less than 5 years exp.  •   Aerospace & Defense

$160K - $200K *

Join a dynamic team as a senior leader driving profitable growth in healthcare services. Oversee sales strategy, lead a high-performing team, and collaborate across functions to deliver innovative sol...

RemoteRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Real Estate & Construction

$88K - $132K *

Drive the development of radar and RF systems for space applications. Collaborate with experienced engineers on design, analysis, and testing of radar subsystems, ensuring innovative solutions in a fa...

Yesterday

  •   Less than 5 years exp.  •   Aerospace & Defense

$125K - $150K *

Transform Advancement Services by providing strategic leadership and operational oversight. Ensure data integrity and enhance fundraising processes while collaborating with teams to drive efficiency a...

Yesterday

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$115K - $158K *

Join our propulsion engineering team to lead the development of advanced spacecraft propulsion systems. You'll oversee system and component ownership, ensuring excellence in design, testing, and proje...

Yesterday

  •   5 - 7 years exp.  •   Aerospace & Defense

$124K - $170K *

Elevate your career by driving spacecraft structural analysis, validating designs, and enhancing performance. Collaborate with cross-functional teams to ensure robust engineering solutions and contrib...

Yesterday

  •   5 - 7 years exp.  •   Aerospace & Defense

$141K - $212K *

Join us to analyze and validate spacecraft structures, guiding design improvements and ensuring performance through rigorous testing and simulations. Collaborate with cross-functional teams to deliver...

Yesterday

  •   8 - 10 years exp.  •   Aerospace & Defense

$141K - $236K *

Drive innovation in aerospace by leading complex mechanical test campaigns, managing projects from design to execution, and collaborating with engineers to enhance test capabilities and infrastructure...

Yesterday

  •   8 - 10 years exp.  •   Aerospace & Defense

$151K - $252K *

Join a team that's shaping the future of space technology by developing cutting-edge avionics hardware. Collaborate across disciplines to drive electrical hardware projects from concept to production...

Yesterday

  •   8 - 10 years exp.  •   Aerospace & Defense

$222K - $247K *

Lead the charge in transforming customer service for enterprise clients by developing success strategies, fostering executive relationships, and driving measurable value through AI adoption and implem...

Yesterday

  •   8 - 10 years exp.  •   Enterprise Technology

$120K - $150K *

Transform complex data center projects by leading design and construction efforts. Collaborate with diverse stakeholders to ensure successful project delivery while managing multiple initiatives acros...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Real Estate & Construction

$115K - $130K *

Join a team that's committed to enhancing regulatory compliance through strategic initiatives, robust IT control design, and effective collaboration across business units to ensure adherence to indust...

RemoteRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Real Estate & Construction

$90K - $145K *

Deliver exceptional patient care in a dynamic step-down unit, supporting those transitioning from ICU. Collaborate with a skilled team to monitor, assess, and advocate for patients, ensuring their com...

Yesterday

  •   11 - 15 years exp.  •   Healthcare

$134K - $231K *

Drive your career with a pivotal role in advancing coronary therapy development. Collaborate across teams to enhance product campaigns, engage key opinion leaders, and deliver innovative educational p...

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Engage with our Technical Support team to tackle complex issues for enterprise health systems. Drive incident resolution, enhance support processes, and mentor junior engineers while shaping the futur...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$134K - $231K *

Transform the interventional landscape by driving product campaigns for coronary therapies. Collaborate across teams to enhance market penetration, develop training programs, and leverage clinical exp...

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Transform supply chain operations by leading procurement, inventory management, and cash planning. Collaborate with cross-functional teams to ensure product delivery, regulatory compliance, and contin...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$230K - $280K *

Unlock potential by providing strategic leadership in DMPK for drug development, guiding programs from discovery to clinical phases. Collaborate across teams to influence key decisions and ensure scie...

Yesterday

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$104K - $135K *

Advance your career by analyzing contractor proposals and costs, developing pricing strategies, and ensuring compliance with regulations. Collaborate with teams to forecast trends and enhance procurem...

Yesterday

  •   Less than 5 years exp.  •   Aerospace & Defense

$104K - $135K *

Optimize contractor proposals through detailed price and cost analyses, ensuring compliance with regulations. Collaborate with teams to forecast trends and develop negotiation strategies, enhancing ov...

Yesterday

  •   Less than 5 years exp.  •   Aerospace & Defense

$97K - $115K *

Drive strategic partnerships by managing key technology alliances, focusing on Microsoft. Collaborate across teams to identify growth opportunities, enhance partner engagement, and align initiatives w...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Technical Services

$120K - $145K *

Join a team that's building and scaling a data and analytics platform to enhance clinical AI performance. Collaborate with cross-functional teams to create actionable insights and drive improvements i...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$175K - $200K *

Join a team that's redefining visual storytelling by architecting innovative generative pipelines and aesthetic standards, ensuring exceptional image quality while preserving identity and user experie...

Yesterday

  •   5 - 7 years exp.  •   Staffing

$175K - $200K *

Engage with us to shape the future of visual technology by defining aesthetic standards and building generative pipelines. Collaborate with engineers to launch innovative styles while championing user...

Yesterday

  •   5 - 7 years exp.  •   Staffing

$135K - $160K *

Drive security initiatives across engineering teams, ensuring robust infrastructure protection while communicating security guarantees to customers and fostering a culture of accountability in securit...

Yesterday

  •   Less than 5 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in California?question toggle

    California listings may include senior and specialized roles in technology, healthcare, finance, life sciences, entertainment, clean energy, manufacturing, and other fields. Available positions depend on current employer needs.

  • Where in California can I search for jobs?question toggle

    You can explore opportunities across the state, including major employment hubs such as Los Angeles, San Francisco, San Diego, San Jose, and Sacramento. Check each posting for its specific location and work arrangement.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for compensation information and details, since pay can vary by position and employer.

  • Can I find remote or hybrid California jobs?question toggle

    Some listings may offer remote or hybrid work, while others require on-site work. The job posting provides the employer’s location and work arrangement requirements.

  • How can I improve my California job search?question toggle

    Narrow your search by role, location, industry, and work arrangement. Keep your resume and profile updated, and carefully compare each opportunity’s qualifications and compensation details.