Explore $100K+ Jobs in California

Discover professional opportunities across California with Ladders. From established business centers to growing regional economies, the state offers senior-level roles in technology, healthcare, finance, entertainment, manufacturing, and more. Browse vetted job listings with salaries of $100,000 or higher and find positions that align with your experience and career goals.

California industries and career opportunities

California’s diverse economy supports leadership and specialized roles at companies of all sizes. Depending on your background, you may find opportunities in software and technology, life sciences, healthcare, financial services, clean energy, media, aerospace, and professional services. Job availability and compensation vary by role, employer, and location.

Find jobs throughout the state

Explore openings in major employment centers such as Los Angeles, San Francisco, San Diego, San Jose, Sacramento, and surrounding communities. Listings may include on-site, hybrid, and remote arrangements; review each posting for its work location and requirements.

Search with Ladders

Use Ladders to focus your search on vetted professional jobs paying $100,000 or more. Review role responsibilities, qualifications, compensation details, and workplace expectations, then apply directly to opportunities that fit your goals. Keep your profile and resume current so employers can better understand your experience.

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1,000+

Jobs in California

Average Salary in USD

Average Salary: $142,597

Sort By: Relevance

$140K - $165K *

Contribute to governance, risk, and compliance initiatives, leading audit remediation for SOC 2, TISAX, and DORA. Drive proactive risk management and maintain stakeholder confidence through transparen...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Media

$74K - $95K *

Lead the charge in patient care coordination, collaborating with healthcare teams to implement individualized care plans, enhance patient engagement, and improve health outcomes while managing a diver...

Today

  •   Less than 5 years exp.  •   Healthcare

$102K - $184K *

Champion compliance initiatives across a multi-state workforce, ensuring adherence to employment laws. Collaborate with HR and legal teams to mitigate risks, develop policies, and provide training, wh...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$122K - $152K *

Advance your career as you manage relationships with C-suite executives, driving revenue and growth through strategic sales efforts in a dynamic, hybrid work environment...

Reposted today

  •   Less than 5 years exp.  •   Finance & Insurance

$85K - $105K *

Drive revenue growth and expand market share in the medical aesthetics sector. Engage in consultative selling, build partnerships, and manage the full sales cycle while ensuring compliance and profita...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$67K - $110K *

Lead the charge in optimizing office operations, fostering collaboration, and enhancing workplace culture while managing administrative support and financial activities to ensure a productive environm...

Today

  •   Less than 5 years exp.  •   Legal & Accounting

$114K - $158K *

Drive financial excellence by leading integrated management of Technology spend, enhancing visibility, and optimizing costs through collaboration with cross-functional teams to improve processes and d...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$139K - $179K *

Transform ambulatory operations to enhance patient care and achieve strategic goals. Lead multidisciplinary teams, manage resources, and ensure compliance with regulations while driving continuous imp...

Reposted today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$240K - $330K *

Unlock potential by driving sales growth in the healthcare sector, managing complex accounts while forming deep relationships. Lead strategic outreach, engaging with executives and refining sales proc...

Reposted today

  •   5 - 7 years exp.  •   Enterprise Technology

$160K - $184K *

Transform workplace well-being by leading behavioral health initiatives, advising HR and executives on complex cases, and implementing strategic programs to enhance employee mental health and safety a...

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$240K - $330K *

Pioneer growth in the healthcare sector by driving new business and cultivating strong client relationships. Utilize expert sales skills to oversee complex deals from prospecting to closing in a consu...

RemoteRemote

Reposted today

  •   5 - 7 years exp.  •   Enterprise Technology

$62K - $119K *

Develop innovative software solutions in C++ and Python for advanced sensor systems. Collaborate with a dynamic team to enhance intelligence and security technologies, while gaining hands-on experienc...

Today

  •   Less than 5 years exp.  •   Aerospace & Defense

$145K - $276K *

Help us lead a space program as a Material Program Manager, optimizing supply chain strategies and managing supplier engagements to achieve program objectives while collaborating with cross-functional...

Reposted today

  •   5 - 7 years exp.  •   Aerospace & Defense

$166K - $210K *

Help us enhance patient care by performing comprehensive optometric evaluations, utilizing advanced diagnostic techniques, and collaborating with healthcare teams to ensure optimal ocular health and v...

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$436K - $500K+*

Lead the charge in developing a high-performing engineering team focused on delivering innovative artwork solutions. Drive operational excellence and partner across functions to enhance product strate...

Today

  •   Less than 5 years exp.  •   Hospitality & Recreation

$250K - $350K *

Lead the charge in designing and executing innovative hardware solutions for an autonomous rail vehicle. Drive technical direction, manage a high-performing engineering team, and ensure successful dep...

Today

  •   8 - 10 years exp.  •   Transportation

$480K - $500K+*

Transform measurement science by leading a skilled team to enhance content performance metrics, ensuring rigorous analysis and fostering individual growth while collaborating with cross-functional lea...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Hospitality & Recreation

$115K - $140K *

Transform the future of drug development by leading the formulation of complex injectable and sterile products, ensuring quality and compliance from research to commercialization while mentoring a dyn...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$180K - $210K *

Join a team that's redefining IT leadership by overseeing strategic operations, enhancing service delivery, and ensuring compliance. Drive innovation and efficiency while aligning IT with business goa...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Business Services

$79K - $120K *

Join us in delivering exceptional MRI services while ensuring patient safety and comfort. Utilize your expertise to perform high-quality imaging and support patients through their experience in a fast...

Today

  •   Less than 5 years exp.  •   Healthcare

$178K - $307K *

Join a team that's redefining surgical vision sales by leading strategic initiatives, driving revenue growth, and fostering cross-functional collaboration to enhance customer engagement and operationa...

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$178K - $307K *

Elevate the U.S. Surgical Vision business by leading sales strategy, driving performance, and fostering cross-functional partnerships. Collaborate with teams to achieve revenue goals and enhance custo...

Irvine, CARemote

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Join a dynamic team to enhance settlement operations, ensuring data integrity and standardized protocols across mass tort resolution programs. Collaborate with attorneys and paralegals to streamline p...

Today

  •   5 - 7 years exp.  •   Legal & Accounting

$110K - $130K *

Elevate customer success by driving strategic partnerships and maximizing product value. Collaborate across teams to ensure seamless implementation and proactive support, while leveraging AI tools to...

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$78K - $90K *

Lead engineering initiatives to design, enhance, and optimize products, ensuring alignment with manufacturing capabilities and performance standards while fostering innovation and usability improvemen...

Reposted today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in California?question toggle

    California listings may include senior and specialized roles in technology, healthcare, finance, life sciences, entertainment, clean energy, manufacturing, and other fields. Available positions depend on current employer needs.

  • Where in California can I search for jobs?question toggle

    You can explore opportunities across the state, including major employment hubs such as Los Angeles, San Francisco, San Diego, San Jose, and Sacramento. Check each posting for its specific location and work arrangement.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for compensation information and details, since pay can vary by position and employer.

  • Can I find remote or hybrid California jobs?question toggle

    Some listings may offer remote or hybrid work, while others require on-site work. The job posting provides the employer’s location and work arrangement requirements.

  • How can I improve my California job search?question toggle

    Narrow your search by role, location, industry, and work arrangement. Keep your resume and profile updated, and carefully compare each opportunity’s qualifications and compensation details.