Explore $100K+ Jobs in Kentucky

Discover high-paying professional opportunities across Kentucky with Ladders. Browse vetted roles with salaries of $100,000 or more, from established employers and growing organizations. Whether you’re interested in positions in Louisville, Lexington, Bowling Green, or elsewhere in the state, find opportunities that fit your experience and career goals.

Professional Opportunities Across Kentucky

Kentucky’s economy spans healthcare, manufacturing, logistics, finance, technology, education, and other industries. Employers across the state seek experienced professionals for roles in leadership, operations, engineering, sales, healthcare administration, and more. The right opportunity may be available in a major metro area or in a smaller community.

Find a Role That Fits Your Experience

Use Ladders to explore opportunities suited to your skills, seniority, and compensation expectations. Review job descriptions, compare responsibilities, and identify roles where your professional background can make an impact. Listings on Ladders are vetted and pay at least $100,000.

Advance Your Career in Kentucky

Build your next career move by searching Kentucky jobs and narrowing results by location, industry, and role. Check listings regularly, tailor your resume to each opportunity, and highlight measurable accomplishments that demonstrate your value to prospective employers.

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$80K - $175K *

Champion the creation of high-quality regulatory documents, managing writing tasks and leading reviews. Collaborate across teams to ensure clarity and compliance, mentoring junior writers while delive...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$140K - $175K *

Transform investment research by evaluating and integrating diverse datasets, enhancing AI-driven workflows, and driving strategic content initiatives to elevate platform value and user experience...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Consumer Technology

$90K - $100K *

Join a team that's passionate about transforming complex scientific data into engaging communications. Collaborate with cross-functional experts to deliver high-quality medical content and strategies...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$200K - $352K *

Shape the future of marketing compliance by leading automation initiatives, overseeing review processes, and driving collaboration across teams. This hands-on role combines strategic oversight with di...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Finance & Insurance

$125K - $150K *

Champion enterprise growth by managing key client relationships, driving retention and revenue expansion. Leverage insights to create strategies, foster collaboration, and enhance client value through...

United StatesRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$170K - $185K *

Elevate user experiences by leading the design of complex healthcare applications. Collaborate with cross-functional teams to create intuitive interfaces that enhance clinical workflows and support hi...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$121K - $161K *

Transform your career by leading the design and implementation of Veeva Vault RIM, ensuring optimal performance and compliance while collaborating with cross-functional teams to enhance user experienc...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$290K - $305K *

Pioneer enterprise sales in Florida, driving value-based solutions for large organizations. Collaborate with cross-functional teams to exceed targets, utilizing strategic partnerships to enhance growt...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$180K - $190K *

Empower our team to drive innovation by developing crucial AI tools that enhance operational efficiency. Oversee governance, training, and metrics to ensure impactful adoption across departments while...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Business Services

$240K - $330K *

Unlock potential by leading a global enablement team to develop and implement a comprehensive strategy that enhances sales effectiveness and drives revenue growth across all customer-facing roles...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$182K - $216K *

Drive operational excellence by leading a 150+ member team, optimizing workflows, and enhancing member experiences through strategic program development and data-driven insights...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Healthcare

$250K - $300K *

Grow your career with a dynamic role leading customer acquisition in GenAI Safety Services. Own the full sales cycle, engage with senior stakeholders, and position strategic AI solutions to drive impa...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $95K *

Manage energy strategies and operations for multiple facilities, ensuring optimal performance of the Central Energy Plant. Mentor staff, oversee maintenance, and implement best practices to enhance en...

1 week ago

  •   Less than 5 years exp.  •   Business Services

$232K - $290K *

Lead the charge in optimizing workforce operations and analytics for multi-condition health care services. Develop strategies for capacity planning, staffing, and analytics to drive efficiency and sup...

United StatesRemote

Reposted 3 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$150K - $180K *

Shape the future of enterprise technology partnerships by driving collaboration with SAP and AWS to enhance market growth, cultivate executive relationships, and implement innovative go-to-market stra...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$82K - $108K *

Grow your career with a dynamic role focused on building relationships and driving sales growth in the wholesale sector. Collaborate with internal teams to deliver exceptional customer service and ach...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$160K - $200K *

Transform the enterprise account management landscape by leading strategy, driving revenue retention, fostering customer growth, and developing high-performing teams to enhance client relationships an...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$152K - $283K *

Deliver impactful field execution by bridging strategy and operations, ensuring initiatives achieve success through proactive risk management and collaboration across teams, all while enhancing accoun...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$135K - $169K *

Accelerate progress at a dynamic startup by driving commercial agreements and managing risk. Collaborate with cross-functional teams to support growth while gaining hands-on experience in a fast-paced...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$139K - $170K *

Empower your career by driving revenue growth and fostering client relationships through effective sales strategies and expert product knowledge in the financial services sector...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$275K - $300K *

Transform customer experiences by leading the multi-location product initiative, driving strategy, and developing innovative solutions that scale across the platform for diverse users, empowering them...

RemoteRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$85K - $100K *

Drive analytical excellence in system implementation and support for commercial operations, collaborating with cross-functional teams to meet business needs and enhance processes in a dynamic Agile en...

2 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$225K - $270K *

Lead the charge in Workforce Transformation by measuring AI’s impact, redesigning roles, and shaping skills for the future. Collaborate with cross-functional leaders to anticipate workforce needs and...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$150K - $180K *

Innovate by leading software engineering excellence and AI adoption; manage cross-functional teams to develop impactful tech solutions while maintaining hands-on involvement with proof-of-concept proj...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Unlock potential by driving analytics and AI solutions for clients, managing a $10M+ portfolio. Collaborate with sales teams to identify opportunities, build value stories, and achieve aggressive sale...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Kentucky?question toggle

    Kentucky listings may include senior and experienced roles in areas such as healthcare, manufacturing, logistics, finance, technology, sales, engineering, and operations. Available positions vary by employer and location.

  • Which Kentucky cities have professional job opportunities?question toggle

    Opportunities may be found in Louisville, Lexington, Bowling Green, and communities throughout the state. Search by location to explore current openings near you.

  • Do jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with advertised salaries of $100,000 or more. Review each listing for its specific compensation details and requirements.

  • How can I find a high-paying job in Kentucky?question toggle

    Search Kentucky listings by city, role, or industry, then review the qualifications and compensation details. Tailor your resume to the position and emphasize relevant accomplishments and leadership experience.