Explore $100K+ Jobs in South Dakota

Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.

South Dakota career opportunities

South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.

Where to find jobs

Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.

Find the right role on Ladders

Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.

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1,000+

Vice President, Sales Jobs in South Dakota

Sort By: Relevance

$125K - $150K *

Lead the charge in optimizing client partnerships through strategic account management and team development, ensuring exceptional service and measurable growth across key accounts in the corporate tra...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Hospitality & Recreation

$170K - $220K *

Lead continuous improvement initiatives across QSR operations, driving cultural transformation and operational excellence. Manage CI strategies, develop leaders, and ensure alignment with enterprise g...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$125K - $157K *

Advance market share and sales objectives by building strong relationships and leveraging clinical expertise. Collaborate with teams to analyze trends and drive strategic initiatives in a dynamic heal...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$175K - $241K *

Empower a high-performing sales team in the Financial Services sector, driving new business growth and fostering long-term client relationships. Lead with a consultative approach to exceed revenue tar...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Consumer Technology

$100K - $150K *

Lead strategic partnerships to drive revenue growth and market presence in the embedded finance ecosystem, ensuring compliance and risk alignment while managing complex enterprise sales cycles and cro...

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $150K *

Lead the charge in driving strategic partnerships and revenue growth within the embedded finance ecosystem, ensuring compliance and risk management while expanding market presence and innovative finan...

Sioux Falls, SDRemote

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$160K - $200K *

Lead the charge in capital formation by raising equity from high-net-worth investors, ensuring timely funding for real estate deals. Build and coach a high-performing team while architecting a vibrant...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$190K - $220K *

Lead the charge in providing strategic legal guidance on complex commercial contracts, enhancing efficiency and compliance while collaborating with cross-functional teams to drive business growth and...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $130K *

Champion eCommerce growth by optimizing digital sales strategies, enhancing customer experiences, and driving operational excellence across DTC channels. Collaborate cross-functionally to leverage ins...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$90K - $115K *

Transform the sales landscape by owning the full cycle for SaaS solutions, building relationships with key stakeholders in K-12 districts, and driving impactful technology adoption to enhance student...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Transportation

$166K - $200K *

Champion innovative solutions by leading cross-functional teams to enhance operational efficiency and drive project success across multiple departments, ensuring alignment with strategic goals and fos...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Elevate your career by building strategic partnerships with top clients, driving renewals and upsells. Own the sales process and collaborate with teams to ensure exceptional service and satisfaction w...

United StatesRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$102K - $122K *

Join a team that crafts innovative commerce and digital strategies for premium clients across various major retail platforms, enhancing their market performance and driving impactful results through c...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$150K - $180K *

Transform cloud operations by leading a team to ensure performance, reliability, and cost-efficiency across multi-cloud environments, while driving incident management and fostering collaboration with...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$80K - $95K *

Take ownership of payroll and equity accounting processes, ensuring accuracy and compliance with GAAP. Collaborate with cross-functional teams and lead process improvements while maintaining documenta...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$103K - $108K *

Transform client relationships as you drive revenue growth through strategic outreach, proposal crafting, and collaboration. Leverage AI tools to enhance efficiency and insights while supporting the s...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Technical Services

$180K - $200K *

Transform federal planning and permitting services by leading multidisciplinary teams, developing strategic growth initiatives, and ensuring compliance with environmental regulations while fostering i...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Real Estate & Construction

$125K - $200K *

Lead the charge in driving sales growth across the East Coast by developing new accounts and implementing strategic sales initiatives. Collaborate with customers to deliver tailored solutions and achi...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$184K - $253K *

Elevate the global equity landscape by leading and refining equity programs with full ownership, impacting multiple jurisdictions and driving compliance while supporting company growth. This role is i...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Business Services

$100K - $120K *

Provide strategic leadership in territory management, driving revenue growth and innovation within complex healthcare environments. Cultivate executive relationships and promote clinical adoption to e...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Drive impactful change by optimizing product operations through collaborative process design, ensuring alignment and efficiency while fostering innovation and simplification across complex product tea...

United StatesRemote

Reposted 4 days ago

  •   8 - 10 years exp.  •   Food & Beverages

$135K - $169K *

Accelerate progress at a dynamic startup by driving commercial agreements and managing risk. Collaborate with cross-functional teams to support growth while gaining hands-on experience in a fast-paced...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$102K - $184K *

Elevate your career by leading market-level financial reporting and performance management in value-based healthcare. Collaborate with stakeholders to drive insights and outcomes, ensuring disciplined...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$200K - $250K *

Make your mark at the forefront of clinical operations, driving global studies from strategy to execution while ensuring operational integration across teams and vendors for successful Phase 3 program...

United StatesRemote

3 weeks ago

  •   15+ years exp.  •   Pharmaceuticals & Biotech

$97K - $133K *

Join a dynamic team to drive sales growth and enhance customer relationships. Manage key accounts, collaborate with cross-functional teams, and ensure exceptional service while achieving ambitious sal...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What types of $100,000-plus jobs are available in South Dakota?question toggle

    Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.

  • Which South Dakota cities have professional job opportunities?question toggle

    Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.

  • How can I find high-paying jobs in South Dakota?question toggle

    Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.

  • Do South Dakota jobs listed on Ladders all pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.