Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
$80K - $95K *
Take ownership of payroll and equity accounting processes, ensuring accuracy and compliance with GAAP. Collaborate with cross-functional teams and lead process improvements while maintaining documenta...
Reposted 2 weeks ago
Partner Manager, Mid-Market, New Business
$103K - $108K *
Transform client relationships as you drive revenue growth through strategic outreach, proposal crafting, and collaboration. Leverage AI tools to enhance efficiency and insights while supporting the s...
1 week ago
Service Line Leader - Integrated Planning & Permitting
$180K - $200K *
Transform federal planning and permitting services by leading multidisciplinary teams, developing strategic growth initiatives, and ensuring compliance with environmental regulations while fostering i...
2 weeks ago
Sales Manager/Key Account Manager (East Coast)
$125K - $200K *
Lead the charge in driving sales growth across the East Coast by developing new accounts and implementing strategic sales initiatives. Collaborate with customers to deliver tailored solutions and achi...
2 weeks ago
$184K - $253K *
Elevate the global equity landscape by leading and refining equity programs with full ownership, impacting multiple jurisdictions and driving compliance while supporting company growth. This role is i...
Reposted 3 weeks ago
Clinical Sales Representative - Atlanta
$100K - $120K *
Provide strategic leadership in territory management, driving revenue growth and innovation within complex healthcare environments. Cultivate executive relationships and promote clinical adoption to e...
Reposted 3 weeks ago
$120K - $145K *
Drive impactful change by optimizing product operations through collaborative process design, ensuring alignment and efficiency while fostering innovation and simplification across complex product tea...
Reposted 4 days ago
$135K - $169K *
Accelerate progress at a dynamic startup by driving commercial agreements and managing risk. Collaborate with cross-functional teams to support growth while gaining hands-on experience in a fast-paced...
3 weeks ago
$102K - $184K *
Elevate your career by leading market-level financial reporting and performance management in value-based healthcare. Collaborate with stakeholders to drive insights and outcomes, ensuring disciplined...
3 days ago
Vice President, Clinical Operations
$200K - $250K *
Make your mark at the forefront of clinical operations, driving global studies from strategy to execution while ensuring operational integration across teams and vendors for successful Phase 3 program...
3 weeks ago
$97K - $133K *
Join a dynamic team to drive sales growth and enhance customer relationships. Manage key accounts, collaborate with cross-functional teams, and ensure exceptional service while achieving ambitious sal...
6 days ago
Director, Enterprise Portfolio Enablement
$110K - $130K *
Drive your career with a strategic role focused on enhancing project management standards and integrating enterprise initiatives. Collaborate with leaders to improve clarity, prioritization, and execu...
3 weeks ago
Senior Business Development Manager, Medical Channel - Northeast
$100K - $115K *
Engage with healthcare professionals to drive growth in the physician-dispensed skincare market. This role involves building relationships, managing accounts, and delivering training to ensure product...
1 week ago
Key Account Manager (Global Strategic Accounts)
$173K - $255K *
Champion strategic global accounts by enhancing operations and communications, driving growth and innovation through insights and strong relationships in the fintech landscape...
Reposted 3 weeks ago
Sales Representative - Nebraska, North and South Dakota - Enabling Technologies
$85K - $100K *
Drive revenue growth by promoting medical device solutions, building customer relationships, and supporting surgical teams. Thrive in a high-performance environment while achieving sales targets and d...
2 days ago
Associate Sales Specialist-Local Government Risk
$150K - $279K *
Transform local government sales by proactively building relationships, generating pipeline, and driving revenue through innovative cloud solutions. Collaborate with a world-class sales team to exceed...
3 weeks ago
Principal Solution Engineer, Global Private Equity & Startups Practice
$157K - $210K *
Transform the landscape of private equity and startups by advising on AI-driven strategies, enhancing deal flow, and driving portfolio-wide value creation through innovative Salesforce solutions and e...
3 weeks ago
Regional Business Director, Southeast
$230K - $260K *
Join us to lead a regional sales team, driving strategic initiatives and fostering relationships to achieve business objectives while enhancing patient outcomes in the oncology sector...
3 days ago
Assistant General Counsel - Corporate, Commercial & Structured Finance
$245K - $310K *
Champion innovative financing solutions as a strategic legal leader, overseeing structured finance, capital markets, and corporate law. Drive legal execution and team growth while ensuring compliance...
4 days ago
Territory Sales Manager (INDIANA) Insurance Experience Required
$97K - $151K *
Transform agency relationships and drive growth by leveraging your insurance expertise. Oversee strategic initiatives, manage agent performance, and deliver impactful training to enhance GEICO's marke...
2 weeks ago
Services Architect, Asset Solutions
$99K - $166K *
Drive impactful solutions as a Services Architect, collaborating with stakeholders to implement Asset Solutions software. Leverage your expertise to understand customer needs, enhance delivery, and en...
3 weeks ago
$120K - $150K *
Elevate your career by designing and delivering innovative video solutions across diverse sectors. Collaborate with teams to create scalable architectures that enhance broadcast, streaming, and cloud...
2 weeks ago
Enterprise Account Executive (Founding Team)
$250K - $280K *
Shape the future of our enterprise sales segment by driving growth and account success. Take ownership of new logo acquisitions, deepen existing client relationships, and establish best practices for...
Reposted 2 weeks ago
$85K - $106K *
Analyze and optimize Amazon DSP and paid search campaigns to drive results across Retail Media. Leverage data insights to enhance performance, ensuring KPI excellence while managing fast-paced, multif...
Reposted 3 weeks ago
$80K - $95K *
Transform your accounting career by managing critical operations for both government contracting and a burgeoning SaaS product line, leading month-end closes, and collaborating across teams to ensure...
3 weeks ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.