Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
$95K - $115K *
Elevate your career by leading regional health and safety initiatives, fostering a culture of safety excellence, and collaborating with stakeholders to implement effective safety management systems ac...
1 week ago
Director, Commerce Strategy & Client Partnerships
$139K - $157K *
Transform client partnerships by leading innovative commerce strategies across major retail platforms. Drive growth through integrated marketing, operational excellence, and creative solutions, ensuri...
1 week ago
Regional Technical Leader - North Region (US)
$100K - $120K *
Empower teams by enhancing technical capabilities across multiple sites, driving operational excellence through hands-on training and support. Engage in troubleshooting and continuous improvement to e...
2 weeks ago
Senior Revenue Operations Leader
$175K - $190K *
Transform revenue operations by leading AI-driven initiatives, optimizing tech stacks, and enhancing cross-functional collaboration. Drive measurable outcomes while building a high-performing team tha...
3 weeks ago
Enterprise Account Executive - FSI
$109K - $207K *
Drive strategic enterprise sales to Fortune 100/500 companies, leveraging strong negotiation skills and a proven track record to exceed quotas in a dynamic and collaborative environment...
Reposted 2 weeks ago
$110K - $130K *
Join a dynamic team to lead and manage multiple large-scale projects, collaborating with diverse stakeholders to deliver innovative software solutions in a global legal environment. Drive project succ...
3 weeks ago
Senior Revenue Operations Program Manager
$145K - $160K *
Drive strategic initiatives by leading complex, cross-functional projects that align stakeholders and transform business priorities into actionable plans, ensuring successful execution across Revenue...
2 weeks ago
Senior Director, Revenue Marketing Services
$327K - $408K *
Lead the charge in shaping long-term marketing strategies and partnerships, overseeing a dynamic team to drive growth and enhance market positioning through innovative co-marketing initiatives and cro...
1 week ago
Senior Director I, Umbrella Product Management
$160K - $190K *
Join a team that's redefining the Umbrella line of business by overseeing P&L, driving innovative strategies, and collaborating across departments to achieve profitable growth and enhance customer sat...
1 week ago
$150K - $175K *
Lead the charge in transforming financial operations while ensuring compliance and accuracy. Collaborate with cross-functional teams to enhance processes, manage audits, and drive strategic initiative...
3 days ago
$110K - $130K *
Join a dynamic team to evaluate strategic investments and growth opportunities in healthcare. Leverage market insights and financial modeling to shape multi-year business strategies, collaborating acr...
3 weeks ago
$107K - $188K *
Unlock potential by managing high-profile accounts and driving sales growth through strategic planning and complex negotiations. Leverage your expertise to develop tailored solutions and exceed revenu...
2 weeks ago
$125K - $150K *
Join a team that's redefining global events management by leading a dynamic program management function. Oversee flagship conferences and regional events, ensuring strategic alignment, operational exc...
2 weeks ago
$180K - $220K *
Empower the revenue team by leading GTM strategy and operations, driving scalable processes and frameworks to support growth from $1B to $2B+. Collaborate across Sales, Marketing, and Finance to enhan...
2 weeks ago
Regional Sales Manager - Southeastern US
$100K - $130K *
Take ownership of sales within a key territory, identifying opportunities and nurturing relationships with clients to drive business growth and exceed sales goals through strategic engagement and effe...
Reposted today
$135K - $160K *
Help us shape the future of pulmonary care by leveraging your clinical expertise to drive product development, enhance workflows, and ensure effective solutions for COPD, asthma, and other pulmonary c...
1 week ago
Key Account Director, Small City (West)
$144K - $200K *
Lead the charge in developing a high-performing sales team focused on public safety. Drive recruitment, coaching, and retention while ensuring team success through strategic deal management and AI int...
5 days ago
$110K - $130K *
Transform client experiences by leading enterprise software implementations. Drive project success with effective stakeholder communication and collaboration across teams while ensuring alignment with...
Reposted 4 weeks ago
Business Development Manager - Technical Sales
$100K - $130K *
Join a team that's focused on driving sales in the oil, gas, and energy sectors. You'll cultivate key customer relationships, execute strategic sales plans, and ensure brand excellence across territor...
Reposted 3 weeks ago
Principal Business Technology Product Manager
$131K - $176K *
Shape the future of sales excellence by owning end-to-end seller experiences. You’ll optimize workflows, create impactful solutions, and directly influence our revenue systems through innovative produ...
Reposted 3 weeks ago
Senior Director, Global ERP Delivery & Solution Architecture
$151K - $314K *
Shape the future of global ERP delivery by leading a diverse team, executing strategic initiatives, and driving transformation across multiple regions to enhance operational efficiency and business va...
1 week ago
Business Development Manager - Central Region
$101K - $139K *
Unlock potential by driving strategic sales initiatives, fostering client relationships, and collaborating across teams to deliver tailored solutions. Engage with customers to assess needs and enhance...
1 week ago
Account Executive, Solutions (TX)
$80K - $95K *
Join a team that's dedicated to transforming literacy in PreK–12 education. Drive new business and foster long-term success by building relationships with key decision-makers and delivering impactful...
1 week ago
$217K - $271K *
Optimize cross-functional program management for a global initiative, ensuring alignment across multiple teams and geographies. Drive execution, manage dependencies, and communicate effectively to del...
4 days ago
Assistant General Counsel - Managed Services Organization
$150K - $235K *
Elevate your legal career by delivering strategic counsel and effective services to Managed Services Organizations and physician practices, while managing complex legal projects and mentoring a team i...
1 week ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.