Explore $100K+ Jobs in Pennsylvania

Discover vetted professional opportunities across Pennsylvania with Ladders. Browse jobs with salaries of $100,000 or more, from senior leadership and management roles to specialized positions in technology, healthcare, finance, engineering, and other fields. Whether you’re looking in Philadelphia, Pittsburgh, Harrisburg, or elsewhere in the state, explore openings that match your experience and career goals.

Find opportunities across Pennsylvania

Pennsylvania’s major cities and regional business centers offer a wide range of professional career paths. Search for opportunities in metropolitan areas such as Philadelphia and Pittsburgh, as well as roles in Harrisburg, Allentown, Lancaster, and other communities. Availability varies by employer and location, so review each listing for work location and remote or hybrid details.

Browse senior and specialized roles

Explore positions for experienced professionals, including director, vice president, executive, and other senior-level roles. You can also find specialized opportunities in areas such as technology, healthcare, finance, sales, operations, and engineering. Review job requirements, responsibilities, and compensation information to identify roles suited to your expertise.

Make your next career move

Use Ladders to explore vetted jobs paying $100,000 or more in Pennsylvania. Compare opportunities, focus your search by location and profession, and apply to positions aligned with your qualifications. New listings may be added as employers seek experienced talent across the state.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

Sort By: Relevance

$88K - $105K *

Join a team that's enhancing purchasing processes through effective EnterpriseOne governance, optimizing setup, and driving efficiency across divisions while supporting community development initiativ...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$139K - $223K *

Join a team that's driving innovative B2B marketing strategies to enhance growth and brand awareness. This role focuses on executing impactful campaigns, leveraging data insights, and collaborating wi...

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$275K - $325K *

Drive the growth of healthcare practices by owning strategy, partnerships, and P&L. Collaborate with teams to deliver tailored financial solutions, while leveraging your network to establish Flex as t...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$122K - $204K *

Shape the future of operations by providing strategic leadership, driving measurable improvements, and fostering cross-functional collaboration to enhance performance, service quality, and customer ou...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$190K *

Lead our product marketing efforts to drive strategy, market growth, and segmentation for innovative public safety software. Collaborate with teams to translate product features into compelling messag...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$115K - $185K *

Lead the charge in optimizing hospital accounts receivable operations, driving cash acceleration, reducing denials, and enhancing revenue realization through strategic partnerships and data-driven dec...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$139K - $250K *

Lead the charge in driving strategic product development for a diverse insurance portfolio, collaborating with stakeholders to enhance performance and achieve revenue targets throughout the product li...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$85K - $100K *

Join a team that's driving growth in premium roofing products by building strategic relationships with key industry players, expanding market share, and providing innovative solutions while managing a...

RemoteRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$107K - $180K *

Drive impactful sales systems solutions by optimizing workflows and integrations. Collaborate cross-functionally to enhance data accuracy and system reliability, ensuring sales teams have the tools th...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$90K *

Unlock your potential with a dynamic role focused on driving growth and engagement in the automotive sector, where your ability to build relationships and analyze data will significantly elevate custo...

RemoteRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$175K - $210K *

Lead operational excellence in biopharmaceutical manufacturing, overseeing GMP processes, technology transfers, and clinical supply. Drive strategic initiatives, manage CDMO relationships, and build a...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Drive operational excellence by leading multi-team managers in executing compliant money movement flows. Collaborate cross-functionally to enhance customer experiences while ensuring risk mitigation a...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$80K - $90K *

Champion project success by managing timelines, resources, and stakeholder communication. Drive seamless implementation experiences while collaborating with cross-functional teams to deliver value-dri...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Drive operational excellence by leading manufacturing expansions and fostering a high-performing culture focused on safety, productivity, and quality. Collaborate with cross-functional teams to align...

4 weeks ago

  •   11 - 15 years exp.  •   Aerospace & Defense

$100K - $120K *

Join a team that's redefining audit and advisory services by driving full-cycle sales of an innovative AI platform. Collaborate with CPA firms to foster relationships and guide them through a transfor...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$76K - $120K *

Shape the future of logistics by driving compliance and optimizing processes to enhance operational excellence and maximize contract value for a dynamic sales organization...

Today

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Support the financial operations by overseeing quarterly reports, managing capital calls, and ensuring compliance with regulations while providing team leadership and training for effective performanc...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$104K - $161K *

Champion growth by managing agency relationships and driving revenue in your territory. Develop and implement best practices to enhance sales performance while analyzing market trends to achieve profi...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$85K - $95K *

Transform client relationships by delivering exceptional service and support, ensuring seamless communication and issue resolution while collaborating with internal teams to enhance client satisfactio...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Legal & Accounting

$95K - $115K *

Transform product vision into reality by leading new product development, managing P&L, and driving market strategies. Collaborate cross-functionally to ensure customer needs are met while optimizing...

3 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$90K - $95K *

Drive success as an experienced seller, managing complex opportunities and building relationships with education leaders to enhance organizational outcomes and improve student success through innovati...

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$160K - $180K *

Elevate your career by driving sales in the U.S. healthcare market, engaging diverse stakeholders, and managing complex sales cycles to expand our national brain-network footprint through strategic pa...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$160K - $200K *

Shape the future of finance operations by leading strategic financial initiatives, overseeing budgeting and reporting, and optimizing revenue cycles while fostering a high-performing team and cross-fu...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$123K - $166K *

Lead and mentor a team of program managers, driving client program success and operational excellence. Collaborate across departments to enhance processes, ensure compliance, and achieve strategic goa...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$135K - $160K *

Lead the strategic design and management of comprehensive benefits programs, ensuring alignment with employee needs and company objectives. Drive innovation and compliance while enhancing employee eng...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Pennsylvania?question toggle

    Pennsylvania listings may include senior management, executive, and specialized professional roles in fields such as technology, healthcare, finance, sales, operations, and engineering. Roles and availability vary by employer.

  • Which Pennsylvania cities have professional job opportunities?question toggle

    Opportunities may be available in Philadelphia, Pittsburgh, Harrisburg, Allentown, Lancaster, and other areas across the state. Check each listing for its specific location and work arrangement.

  • Are these Pennsylvania jobs vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review individual listings for details about the employer, qualifications, responsibilities, and compensation.

  • Can I find remote or hybrid jobs in Pennsylvania?question toggle

    Some employers may offer remote or hybrid arrangements, but availability varies. Check the work-location details in each job listing.